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Prevacid Alternatives

(Lansoprazole)

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Compare Prevacid (Lansoprazole) to alternatives

These medications are comparable to Prevacid (Lansoprazole) or used for similar purposes.

Prevacid
(Lansoprazole)

Nexium
(Esomeprazole)

Prilosec
(Omeprazole)

Treats heartburn and stomach ulcers. Prevacid (Lansoprazole) gives you long-lasting heartburn relief and helps heal ulcers.Treats heartburn and stomach ulcers. Nexium (Esomeprazole) gives you long-lasting heartburn relief. But this purple pill ain't cheap! The generic forms of alternative drugs work just as well, and are usually less expensive.Treats heartburn and stomach ulcers. Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.
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Reviews & ratings
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Reviews for Nexium (Esomeprazole)
75%
+8% vs. Prevacid (Lansoprazole)
59%
8% vs. Prevacid (Lansoprazole)
11%
3% vs. Prevacid (Lansoprazole)
Reviews for Prilosec (Omeprazole)
80%
+13% vs. Prevacid (Lansoprazole)
59%
8% vs. Prevacid (Lansoprazole)
7%
+1% vs. Prevacid (Lansoprazole)
Side effects
PrevacidNexiumOmeprazole
  • Diarrhea 2%
  • Abdominal pain 1%
More Prevacid side effects »

The Nexium FDA package insert doesn’t have numbers about how common side effects are.

More about Nexium side effects »

The Omeprazole FDA package insert doesn’t have numbers about how common side effects are.

More about Omeprazole side effects »
How it works
PrevacidNexiumOmeprazole
Prevacid (Lansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Nexium (Esomeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.
Type of medication
PrevacidNexiumOmeprazole
Acid reducer
Proton pump inhibitor
Prescription or OTC
Acid reducer
Proton pump inhibitor
Prescription or OTC
Acid reducer
Proton pump inhibitor
Prescription or OTC
Available as
PrevacidNexiumOmeprazole
  • Extended release
  • Dissolving tablet extended release
  • Extended release
  • Extended release
Used for (click to learn more)
PrevacidNexiumOmeprazole
Risk factors for serious side effects
PrevacidNexiumOmeprazole
    • Helicobacter pylori infection
    • Autoimmune disease
    • Being hospitalized
    • Antibiotic use
    • Osteoporosis
    • Age 50 or older
    • Using high medication doses
    • Long-term therapy (1 year or more)
    • Smoking
    • Use of other medications that weaken bones
      Detailed Prevacid (Lansoprazole) risks & warnings »
      Coming soon.Coming soon.
      Pregnancy category
      PrevacidNexiumOmeprazole
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
      Food
      • Take Prevacid (Lansoprazole) about 1 hour before a meal.
      • Take 1 hour before a meal.
      • Take 1 hour before a meal.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      PrevacidNexiumOmeprazole
      • Most people can take Prevacid (Lansoprazole) without any noticeable day-to-day side effects.
      • Prevacid (Lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
      • Sometimes if one PPI doesn't work, another medication in the same class will work for you.
      • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
      • Available as both a generic and over-the-counter option, so it's pretty affordable.
      • Most people can take Nexium without any noticeable day-to-day side effects.
      • Nexium lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
      • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
      • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
      • Available as both a generic and over-the-counter option, so it's pretty affordable.
      • Most people can take Omeprazole without any noticeable day-to-day side effects.
      • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
      • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
      • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
      • Available as both a generic and over-the-counter option, so it's pretty affordable.
      Downsides and risks
      PrevacidNexiumOmeprazole
      • Depending on the condition you are treating, it can take one to two weeks to get the full effect.
      • If you are taking Prevacid (Lansoprazole) for a long time you should take a calcium supplement to prevent fragile bones.
      • Can interact with other drugs, so be sure your doctor knows all the medicine you're taking before starting Prevacid (Lansoprazole).
      • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
      • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Nexium long-term.
      • Can be expensive—especially the purple brand-name pill. Other alternatives are usually cheaper than Nexium and work just as well.
      • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Nexium.
      • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
      • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
      • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
      • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
      • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
      • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
      • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
      Tips from our pharmacists for people taking the medication
      PrevacidNexiumOmeprazole
      • Take Prevacid (Lansoprazole) about 1 hour before a meal.
      • Don't chew or crush capsules, but swallow them whole.
      • If you have trouble swallowing, there's a tablet available that dissolves in your mouth.
      • Give Prevacid (Lansoprazole) a chance to work. You'll see some benefits right away, but the full effects can take a week or so to kick in.
      • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Prevacid (Lansoprazole).
      • When using Nexium long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
      • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Nexium.
      • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Nexium.
      • Take 1 hour before a meal.
      • Don't chew or crush capsules; swallow them whole.
      • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
      • When using Omeprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
      • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Omeprazole.
      • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
      • Take 1 hour before a meal.
      • Don't chew or crush capsules; swallow them whole.
      • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
      Learn more
      More about PrevacidSide effectsReviews & ratingsAlternativesFDA package insert
      More about NexiumSide effectsReviews & ratingsFDA package insert
      More about OmeprazoleSide effectsReviews & ratingsFDA package insert