Prescription or OTCLower-cost generic availableClass: Gastrointestinal

Prilosec

(omeprazole)

Prescription or OTCLower-cost generic availableClass: Gastrointestinal
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5.53Omeprazole

Treats heartburn and stomach ulcers.

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Our bottom line

Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.

Prices and discounts
Lowest price for 30 20mg capsules
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$4.00
  • Price before coupon
    $23.53
  • Lowest price with coupon
    $4.00
    83% savings

Upsides

  • Most people can take Omeprazole without any noticeable day-to-day side effects.
  • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
People’s experience with Omeprazole

1167reviews so far. What do you think?

Worth itNot sureNot worth it

Downsides

  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
  • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
  • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
Prices and discounts
Lowest price for 30 20mg capsules
Determining your location...
$4.00
  • Price before coupon
    $23.53
  • Lowest price with coupon
    $4.00
    83% savings
How it works

Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.

People’s experience with Omeprazole

1167reviews so far. What do you think?

Worth itNot sureNot worth it
Dosage forms
  • Extended release

What to expect when you take Prilosec (omeprazole) for Reduces stomach acid

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Side effect rates for Prilosec (omeprazole)

3096 From clinical trials of Omeprazole / All
  • Upper respiratory infection
  • Fever
  • Upper respiratory infection
  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Accidental injuries
  • Flatulence
  • Vomiting

Risks and Warnings for Prilosec (omeprazole)

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  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Prilosec (Omeprazole) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Prilosec (omeprazole)

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Pregnancy
Interactions
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
Food
  • Take 1 hour before a meal.