Prilosec

(Omeprazole)

4.0/ 5 average rating with 1167 reviewsforOmeprazole
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Treats heartburn and stomach ulcers.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.

Quick facts about Omeprazole
  • Drug class: Gastrointestinal
  • Rx status: Prescription or OTC
  • Generic status: Lower-cost generic available (omeprazole)
Prices and discounts
Lowest price for 30 20mg capsules
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$6.25
  • Price before coupon
    $23.53
  • Lowest price with coupon
    $6.25
    73% savings

Upsides

  • Most people can take Omeprazole without any noticeable day-to-day side effects.
  • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.

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What to expect from Omeprazole, on one page

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People’s experience with Omeprazole

1167reviews so far. What do you think?

Downsides

  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
  • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
  • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.

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Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Omeprazole, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 30 20mg capsules
Determining your location...
$6.25
  • Price before coupon
    $23.53
  • Lowest price with coupon
    $6.25
    73% savings
How it works

Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.

Quick facts about Omeprazole
  • Drug class: Gastrointestinal
  • Rx status: Prescription or OTC
  • Generic status: Lower-cost generic available (omeprazole)

Dosage forms

  • Extended release
People’s experience with Omeprazole

1167reviews so far. What do you think?

What to expect when you take Prilosec (Omeprazole) for Reduces stomach acid

Skip what to expect section. Skip to side effects section.
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Prilosec (Omeprazole)

From 3096 clinical trials of Omeprazole when taken for any indication
  • Upper respiratory infection
  • Fever
  • Upper respiratory infection
  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Accidental injuries
  • Vomiting
  • Flatulence

Risks and Warnings for Prilosec (Omeprazole)

Skip risks section. Skip to common concerns section.
  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Prilosec (Omeprazole) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Prilosec (Omeprazole)

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Pregnancy
Price
  • Reviewed Omeprazoleon 8/28/2017Buy at COSTCO for about $20/6 weeks OTC = other the counter
    66
    Man
    Two years or more
    Gastroesophageal Reflux Disease (GERD)
Interactions
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
  • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
Food
  • Take 1 hour before a meal.