Crinone

(Progesterone Vaginal Gel)

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Regulates your menstrual cycle and supports fertility treatments.

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Our bottom line

Crinone (Progesterone Vaginal Gel) is a long-acting vaginal gel used in fertility treatments, and you don't have to apply it as often as progesterone vaginal inserts.

Quick facts about Progesterone Vaginal Gel
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 21.75 1.45g of 8% applicators
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$522.12

Upsides

  • Helps increase your chances of getting pregnant.
  • Regulates your menstrual cycle.
  • Exposes your body to less hormone compared to progesterone pills or injections.
  • Crinone (Progesterone Vaginal Gel) replaces low levels of progesterone to prepare the lining of your uterus to receive and nourish a fertilized egg. If you become pregnant, Crinone (Progesterone Vaginal Gel) can be used for another 10 to 12 weeks until your progesterone levels are high enough.
  • Women can also use Crinone (Progesterone Vaginal Gel) to treat secondary amenorrhea (the absence of menstrual cycles in women who used to have a regular period) due to a decrease in the hormone progesterone. Crinone (Progesterone Vaginal Gel) is used to bring the hormone levels back up to normal.
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Downsides

  • Crinone (Progesterone Vaginal Gel) can cause vaginal irritation and burning.
  • Inserting the applicator can possibly cause discomfort or infection.
  • Crinone (Progesterone Vaginal Gel) can cause a white vaginal discharge a few days after taking the medicine, so wearing a panty liner can make you feel more comfortable.
  • You can't use tampons or other vaginal products for at least 6 hours before and 6 hours after using Crinone (Progesterone Vaginal Gel).
How it works

Crinone (Progesterone Vaginal Gel) contains progesterone, one of the hormones essential for maintaining a pregnancy. Women on fertility treatment can take progesterone to prepare the lining of the uterus to receive and nourish a fertilized egg.

Quick facts about Progesterone Vaginal Gel
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Female infertility
  • Amenorrhea

Dosage forms

  • Vaginal cream, gel, or ointment
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Side effect rates for Crinone (Progesterone Vaginal Gel)

62 From clinical trials of Progesterone Vaginal Gel / Amenorrhea (4% gel)
  • Pruitis genital
  • Abdominal Pain
  • Appetite Increased
  • Upper Respiratory Tract Infection
  • Nausea
  • Back Pain
  • Myalgia
  • Vaginal Discharge
  • Bloating
  • Sleep Disorder

Risks and Warnings for Crinone (Progesterone Vaginal Gel)

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    • Higher risk if:
    • Personal or family history of breast cancer

    It is not completely clear if progestin, like as Crinone (Progesterone Vaginal Gel), increases your risk of breast cancer. There may be a higher risk if you have a history of breast cancer, so make sure to get routine breast exams.

Common concerns from people taking Crinone (Progesterone Vaginal Gel)

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Pregnancy
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  • Crinone (Progesterone Vaginal Gel) contains progestin. It could cause a higher risk of ovarian cancer, especially if you have a family history of it. Your doctor can help you weigh the risks versus the benefits of this medication.