Prescription onlyClass: Dermatologic



Prescription onlyClass: Dermatologic
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Treats eczema.

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Our bottom line

Astagraf (Tacrolimus) is effective at treating eczema if other options haven’t helped, but its long-term effects aren’t well known. Your doctor will decide how long you should use it for.

Price and discounts
Best available price for 120 (1mg) capsules of tacrolimus


  • Astagraf (Tacrolimus) is effective at treating eczema, if other options haven’t worked or shouldn’t be used.
  • Many people see an improvement in their skin in as early as one week.
  • Doesn’t have alcohol in it, so it won’t dry your skin out.


  • Not available in a generic form.
  • Can’t be used in children under ages 2 years old.
  • Can’t be used if your immune system is weak (for example, if you have cancer or are taking steroids for a long time).
  • Not recommended to be used for a very long period of time. If you have to keep using Astagraf (Tacrolimus), your doctor will probably have you take breaks in-between.
How it works

Astagraf (Tacrolimus) is a topical calcineurin inhibitor. It works by blocking the inflammatory process, so your skin won’t react as much to irritants that make your eczema worse.

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Side effect rates for Astagraf (tacrolimus)

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These are side effects of Astagraf (tacrolimus) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Astagraf (tacrolimus)

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  • Cancers of the skin and lymphatic system have been reported in patients using Astagraf (Tacrolimus). However, this is very rare, and it hasn’t been established that Astagraf (Tacrolimus) causes these malignancies. You should apply Astagraf (Tacrolimus) only to the affected areas of your skin, and use for short periods only. Your doctor will decide how long you should be using Astagraf (Tacrolimus).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Astagraf (tacrolimus)

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  • Doesn’t have alcohol in it, so it won’t dry your skin out.