Prescription onlyLower-cost generic availableClass: Dermatologic

Protopic

(tacrolimus)

Prescription onlyLower-cost generic availableClass: Dermatologic
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Treats moderate to severe eczema.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Protopic (tacrolimus) is effective at treating eczema when other options haven’t helped, but its long-term effects on the body aren’t well known.

Prices and discounts
Lowest price for 120 1mg capsules
Determining your location...
$47.32

Upsides

  • Protopic (tacrolimus) is more effective than the similar medications.
  • Protopic (tacrolimus) is stronger than some steroids, making it a good option if similar medications have not worked for you.
Tried Protopic? Write a review!
Worth itNot sureNot worth it

Downsides

  • Is not a first-line option for eczema due to the risk of cancer.
  • Protopic (tacrolimus) can't be used if your immune system is weak (for example, if you have cancer or have been taking steroids for a long time).
  • Not recommended to be used for a very long period of time. If you have to keep using Protopic (tacrolimus), your doctor will have you take breaks in-between.
Prices and discounts
Lowest price for 120 1mg capsules
Determining your location...
$47.32
How it works

Protopic (tacrolimus) is a topical calcineurin inhibitor. It works by blocking the inflammatory process, so your skin won’t react as much to irritants that make your eczema worse.

Tried Protopic? Write a review!
Worth itNot sureNot worth it
Used for
Dosage forms
  • Ointment

What to expect when you take Protopic (tacrolimus) for Eczema

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Protopic (tacrolimus)

422 From clinical trials of Protopic / Eczema (0.03%)
  • Skin burning
  • Itching
  • Skin redness
  • Flu-like symptoms
  • Headache
  • Allergic reaction
  • Skin infection
  • Asthma
  • Inflammation of the hair follicles
  • Rash

Risks and Warnings for Protopic (tacrolimus)

Skip risks section. Skip to common concerns section.
  • There is rare chance that Protopic (tacrolimus) can cause skin and lymphoma cancer. You can help prevent this by using Protopic (tacrolimus) as directed, not for more than or longer than prescribed by your doctor. Try to keep Protopic (tacrolimus) only on the treatment areas and away from healthy skin.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Protopic (tacrolimus)

Final section. Do you want to return to drug navigation?
Kidneys and liver
  • Rarely, Protopic (tacrolimus) can cause sudden kidney failure. Speak to your doctor if you currently have kidney problems.