Prescription onlyLower-cost generic available

Reglan

(Metoclopramide)

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Treats heartburn and nausea.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Reglan (Metoclopramide) helps get your digestive system moving and lowers nausea and vomiting. Using it a long time can come with serious, potentially permanent side effects.

  • Reglan (Metoclopramide) stops the chance of vomiting for about one-third of the people who take it.
  • Gets stomach fluids moving after surgery or during diabetic gastroparesis. Works well for acid reflux when other medications don’t.
  • Comes in a generic version, and in multiple forms.
  • You can’t use Reglan (Metoclopramide) for more than 12 weeks since it can lead to involuntary movements of the eyes, tongue, face, arm, or legs.
  • Reglan (Metoclopramide) is no longer recommended for acid reflux because of its long list of side effects and the availability of better medications.
  • It can take several weeks for Reglan (Metoclopramide) to begin working for diabetic gastroparesis.
  • If you take Reglan (Metoclopramide) for more than 12 weeks, there can be serious side effects and you'll have to get your blood checked often.

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Side effects for Reglan (Metoclopramide)

From clinical trials of Reglan / Nausea and vomiting from chemotherapy ( 174)

  • HeadacheHeadache5% for Reglan vs.4% for placebo
  • NauseaNausea4% for Reglan vs.6% for placebo
  • VomitingVomiting2% for Reglan vs.1% for placebo
  • FatigueFatigue2% for Reglan vs.3% for placebo
  • DrowsinessDrowsiness2% for Reglan vs.3% for placebo
  • DizzinessDizziness1% for Reglan vs.4% for placebo

What to expect when you take Reglan (Metoclopramide)

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Tips from our pharmacists
  • Reglan (Metoclopramide) can cause drowsiness, so avoid driving and other activities that require you to be alert.
  • Most doctors prescribe Reglan (Metoclopramide) 4 times a day, 30 minutes before each meal, and before bed.
  • Don’t drink alcohol or take with other drugs that slow your body down until you know how Reglan (Metoclopramide) affects you.
  • Contact a doctor immediately if you begin to have repetitive movements of the eyes, tongue, face, arm, or legs.
  • It can take several weeks before Reglan (Metoclopramide) works best for diabetic gastroparesis; so don’t give up on it.

Risks and Warnings for Reglan (Metoclopramide)

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    • Higher risk if:
    • Elderly
    • Women
    • Diabetics

    Reglan (Metoclopramide) can cause muscle stiffness, feelings of restlessness (like you need to move around), and abnormal or uncontrollable facial or body movements, which could be a sign of tardive dyskinesia (TD). Let your doctor know if you experience any of these symptoms. Reglan (Metoclopramide) should not be taken for more than 12 weeks, because these symptoms can become permanent. There is currently no known effective treatment for TD, although, in some patients TD may go away.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Reglan (Metoclopramide)

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The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Alcohol
  • Tips from our pharmacists
  • Don’t drink alcohol or take with other drugs that slow your body down until you know how Reglan (Metoclopramide) affects you.
Food
  • Tips from our pharmacists
  • Most doctors prescribe Reglan (Metoclopramide) 4 times a day, 30 minutes before each meal, and before bed.
Sleep
  • Tips from our pharmacists
  • Reglan (Metoclopramide) can cause drowsiness, so avoid driving and other activities that require you to be alert.
  • I took this for gastroparesis of no known cause. Helped with the pain, but not with the nausea or appetite. Immediately felt sheer TERROR to the point where I had to ask my family to sleep next to me. Caused hands to shake.
    Age: 26
    Gender: Woman
    Taken for: Stomach emptying problem caused by diabetes