Prescription onlyLower-cost generic available

Risperdal

(Risperidone)

  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
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Helps control your thoughts and mood.

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Prescription onlyLower-cost generic available

Our bottom line

Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.

Upsides

  • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
  • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
  • Antipsychotic medicines are all about equally effective.
  • Less likely to cause heart problems than some antipsychotics.

Downsides

  • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.

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What to expect when you take Risperdal (Risperidone) for Schizophrenia

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Tips from our pharmacists
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Can cause dizziness and drowsiness.
  • For the first week, avoid activities that require you to be alert.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take it.
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Side effects for Risperdal (Risperidone)

From clinical trials of Risperdal / Pediatric schizophrenia (1-3 mg per day)  ( 109)

  • Relaxation or sleepinessRelaxation or sleepiness24% for Risperdal vs.4% for placebo
  • ParkinsonismParkinsonism16% for Risperdal vs.11% for placebo
  • TremorTremor11% for Risperdal vs.6% for placebo
  • RestlessnessRestlessness9% for Risperdal vs.4% for placebo
  • DizzinessDizziness7% for Risperdal vs.2% for placebo
  • AnxietyAnxiety7% for Risperdal vs.0% for placebo
  • Muscle twitchingMuscle twitching2% for Risperdal vs.0% for placebo

Manufacturers don’t say how common these side effects are

  • Excessive saliva

Risks and Warnings for Risperdal (Risperidone)

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    • Higher risk if:
    • Elderly patients with dementia

    Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Risperdal (Risperidone) is not approved to treat dementia-related psychosis.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Risperdal (Risperidone)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Food
  • Risks from our pharmacists
  • Risperdal (Risperidone) can increase your blood sugar and cholesterol. Exercise and eat healthy food to lower your risk.
  • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
Sex
  • kept away the psychosis but at a huge cost. I gained a lot of weight, became depressed, lost sex drive, anhedonia, and I also lost my job because I couldn't be creative anymore (was a writer before I started taking it). Can't focus, and I found out that I lost several IQ points after I started taking it.
  • Worked well for my mood swings and hallucinations. Two problems I've had are weight gain and sex drive. I've gained 100 pounds in a year and haven't had a sex drive since I started it and can't get an erection.
  • Loss of sexual drive, haven't gotten it back after a year off the medication. Just want to die. Wouldn't recommend.
Sleep
  • Tips from our pharmacists
  • Can cause dizziness and drowsiness.
  • Drowsiness
  • I have scabs all over my body, my skin is dry and flaking off I have popped blood vessels and bruises all over my body from scratching so much. Getting off it tomorrow, HOWEVER did help me sleep without waking up with nightmares every night
Weight
  • Upsides and downsides from our pharmacists
  • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • Tips from our pharmacists
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Risks from our pharmacists
  • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
  • kept away the psychosis but at a huge cost. I gained a lot of weight, became depressed, lost sex drive, anhedonia, and I also lost my job because I couldn't be creative anymore (was a writer before I started taking it). Can't focus, and I found out that I lost several IQ points after I started taking it.
  • Worked well for my mood swings and hallucinations. Two problems I've had are weight gain and sex drive. I've gained 100 pounds in a year and haven't had a sex drive since I started it and can't get an erection.
  • been on it a few months, better than seroquel & no weight gain