Over-the-counterLower-cost generic available



  • Liquid
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Breaks up mucus that causes cough.

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Over-the-counterLower-cost generic available

Our bottom line

Robitussin (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, but it doesn't last as long as other guaifenesin products.


  • Robitussin (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
  • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
  • Available in multiple forms.
  • Can be used in children 12 years and older.


  • Robitussin (Guaifenesin) doesn't last as long as other products that contain guaifenesin. Mucinex's extended release form lasts 12 hours and Robitussin (Guaifenesin)'s lasts 8 hours.
  • You need to drink a lot of fluids while taking this medication or it won't work as well.
  • Robitussin (Guaifenesin) isn’t useful if you have a dry cough.
  • Can cause nausea, headache, and an upset stomach.

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What to expect when you take Robitussin (Guaifenesin)

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Tips from our pharmacists
  • Drink plenty of fluids while taking Robitussin (Guaifenesin) because liquid helps break down mucus.
  • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
  • Follow age-specific dosing instructions on how much to take.
  • If your cough lasts more than 7 days, call your doctor.
  • Robitussin (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
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Side effects for Robitussin (Guaifenesin)

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These are side effects of Robitussin (Guaifenesin) reported to the FDA by people taking it, and by doctors and pharmacists.

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Risks and Warnings for Robitussin (Guaifenesin)

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  • Some people taking Robitussin (Guaifenesin) have reported nausea and vomiting. This is very rare and usually not serious. However, if you develop a fever with the nausea and vomiting, then talk to your doctor right away.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Robitussin (Guaifenesin)

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The FDA category for this medication is N. It is advised that you: Unknown
  • It can make you a bit drowsy