Over-the-counterLower-cost generic available

Robitussin Daytime Cold Plus Flu

(Acetaminophen / Dextromethorphan / Phenylephrine)

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Relieves cold and flu symptoms.

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Over-the-counterLower-cost generic available

Our pharmacists’ bottom line

Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is good for multiple cold and flu symptoms, but it's more medicine than you need if you only have one symptom.

  • Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold and flu symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
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Side effects for Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine)

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These are side effects of Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine)

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Tips from our pharmacists
  • Starts working in about 30 minutes.
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.

Tips from pharmacists and people taking Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine)

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The FDA category for this medication is N. It is advised that you: Unknown
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