Over-the-counterLower-cost generic availableClass: Respiratory

Robitussin Daytime Cold Plus Flu 

(acetaminophen / dextromethorphan / phenylephrine)

Over-the-counterLower-cost generic availableClass: Respiratory
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Relieves cold and flu symptoms.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is good for multiple cold and flu symptoms, but it's more medicine than you need if you only have one symptom.

Upsides

  • Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold and flu symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.

Downsides

  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
How it works

Robitussin Daytime Cold Plus Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.

Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Robitussin Daytime Cold Plus Flu (acetaminophen / dextromethorphan / phenylephrine)

0 reports
These are side effects of Robitussin Daytime Cold Plus Flu (acetaminophen / dextromethorphan / phenylephrine) reported to the FDA by people taking it, and by doctors and pharmacists.
Filter group. All currently selected
Filter group. All currently selected

Common concerns from people taking Robitussin Daytime Cold Plus Flu (acetaminophen / dextromethorphan / phenylephrine)

Final section. Do you want to return to drug navigation?
Pregnancy
Kidneys and liver
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Pain
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.