Treats bipolar disorder and schizophrenia.
Our bottom line
While Saphris (asenapine) has fewer side effects compared with other medicines that treat bipolar disorder and schizophrenia, it can be more expensive.
- Saphris (asenapine) can be used to treat bipolar disorder in children age 10 or older, and schizophrenia in children age 12 or older.
- You don't need water to take Saphris (asenapine); the pill dissolves in your mouth right away.
- Compared to other medicines, the side effects of Saphris (asenapine) are milder.
- Saphris (asenapine) is only available as a brand name.
- Compared to other medicines, Saphris (asenapine) can cause changes in your hormones and make you sleepy.
- You have to take Saphris (asenapine) twice a day, which can be hard to remember.
While it's not clear how Saphris (asenapine) helps to treat bipolar disorder or schizophrenia, it changes the amount of dopamine and serotonin in the brain, two chemicals that are known to regulate mood.
What to expect when you take Saphris (asenapine) for SchizophreniaSkip what to expect section. Skip to Risks & Warnings section.
Side effect rates for Saphris (asenapine)
- Trouble sleeping
- Difficulty controlling movements
- Numbness in the mouth
- Swelling in the arms and legs
- Weight gain
- High blood pressure
Risks and Warnings for Saphris (asenapine)Skip risks section. Skip to common concerns section.
- Higher risk if:
- › People age 65 or older with dementia and psychosis
Older people who have dementia and psychosis have a higher risk of death if they take antipsychotic medicines like Saphris (asenapine). They shouldn't be given this medicine.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Saphris (asenapine)Final section. Do you want to return to drug navigation?
- People on medicines like Saphris (asenapine) have had weight gain and higher blood sugar to the point of having diabetes. Your doctor will work with you to stop that from happening.