Lower-cost generic availableClass: Neuro/psych

Silenor 

(doxepin)

Lower-cost generic availableClass: Neuro/psych
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Helps you relax, and sleep.

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Our bottom line

Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.

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Best available price for 30 (10mg) capsules of doxepin
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Upsides

  • In a clinical trial Doxepin was able to significantly improve sleep quality.
  • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
  • Once your body gets used to Doxepin, most of the side effects go away.
  • Doxepin comes in a generic form, so it is pretty cheap.
  • Doxepin is not addictive.

Downsides

  • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
  • Doxepin can increase your appetite, leading to weight gain.
  • Taking Doxepin can make emptying your bladder difficult.
  • Some people have suicidal thoughts when taking Doxepin.
  • Doxepin can interact with many different medications, vitamins, and alternative treatments.
How it works

Doxepin is a tricyclic antidepressant. It keeps norepinephrine and serotonin in your brain longer, helping you relax, and sleep. It also blocks the chemical that causes itch, and wakefulness.

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Side effect rates for Silenor (doxepin)

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These are side effects of Silenor (doxepin) reported to the FDA by people taking it, and by doctors and pharmacists.
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Common concerns from people taking Silenor (doxepin)

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Pregnancy
Interactions
  • Doxepin can interact with many different medications, vitamins, and alternative treatments.
Alcohol
  • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
Weight
  • Doxepin can increase your appetite, leading to weight gain.