Lower-cost generic availableClass: Neuro/psych

Silenor Alternatives

(doxepin)

Lower-cost generic availableClass: Neuro/psych
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Compare Silenor (doxepin) to alternatives

These medications are comparable to Silenor (doxepin) or used for similar purposes.

Silenor
(doxepin)

Prosom
(estazolam)

Restoril
(temazepam)

Halcion
(triazolam)

Benadryl
(diphenhydramine)

Anafranil
(clomipramine)

Dalmane
(flurazepam)

Limbitrol
(chlordiazepoxide / amitriptyline)

Oleptro
(trazodone)

Norpramin
(desipramine)

Ambien
(zolpidem)

Asendin
(amoxapine)

Ativan
(lorazepam)

Helps you relax, and sleep. Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.Helps you stay asleep longer. Prosom (estazolam) can help you sleep, but you might feel hungover the next day.Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.Helps you stay asleep. Halcion (triazolam) can be used to help you fall asleep, but your body can become used to it very quickly.Treats allergy symptoms and helps you sleep. Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.Helps with your actions. Anafranil (Clomipramine) is helpful in treating OCD, but it can have a lot of side effects.Helps you fall asleep. Dalmane (flurazepam) helps you fall asleep, but its effect can carry over to the next day and be addictive.Treats anxiety and depression. While Limbitrol (chlordiazepoxide / amitriptyline) as a combination can be used to treat both anxiety and depression, other medicines are considered first choice because chlordiazepoxide can be potentially addicting.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.Stabilizes your mood. Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.Helps you sleep. Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.Stabilizes your mood. While Asendin (amoxapine) can treat depression, you have to take it several times a day and it can make you feel sleepy.Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Silenor (doxepin)?
Worth itNot sureNot worth it

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Have you used Prosom (estazolam)?
Worth itNot sureNot worth it
Reviews for Restoril
65%
+35% better vs. Silenor
55%
-5% worse vs. Silenor
16%
+16% better vs. Silenor
Have you used Restoril (temazepam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Halcion (triazolam)?
Worth itNot sureNot worth it
Reviews for Benadryl
86%
+14% better vs. Silenor
59%
-9% worse vs. Silenor
8%
+8% better vs. Silenor
294 reviews
Have you used Benadryl (diphenhydramine)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Anafranil (clomipramine)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Dalmane (flurazepam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Limbitrol (chlordiazepoxide / amitriptyline)?
Worth itNot sureNot worth it
Reviews for Oleptro
73%
+27% better vs. Silenor
49%
+1% better vs. Silenor
24%
+24% better vs. Silenor
Have you used Oleptro (trazodone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Norpramin (desipramine)?
Worth itNot sureNot worth it
Reviews for Ambien
67%
+33% better vs. Silenor
50%
Same vs. Silenor
16%
+16% better vs. Silenor
1375 reviews
Have you used Ambien (zolpidem)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Asendin (amoxapine)?
Worth itNot sureNot worth it
Reviews for Ativan
71%
+29% better vs. Silenor
51%
-1% worse vs. Silenor
15%
+15% better vs. Silenor
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
Side effects
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan

We haven’t found good data for Silenor side effects.

FDA side effect reports for Silenor »
  • Sleepiness 15%
  • Weakness 3%
  • Difficulty controlling muscles 4%
  • Dizziness 4%
  • Abnormal coordination 3%
  • Leg and foot pain 1%
More Estazolam side effects »

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »
  • Drowsiness 8%
  • Headache 2%
  • Dizziness 5%
  • Nausea and vomiting 1%
  • Difficulty controlling movements 4%
  • Lightheadedness 4%
More triazolam side effects »

We haven’t found good data for Benadryl side effects.

FDA side effect reports for Benadryl »
  • Dry mouth 67%
  • Tremor 52%
  • Dizziness 40%
  • Drowsiness 38%
  • Headache 11%
  • Constipation 36%
  • Ejaculation failure 40%
  • Fatigue 21%
More Anafranil side effects »

The Dalmane FDA package insert doesn’t have numbers about how common side effects are.

More about Dalmane side effects »

The chlordiazepoxide / amitriptyline FDA package insert doesn’t have numbers about how common side effects are.

More about chlordiazepoxide / amitriptyline side effects »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Headache 6%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Nausea 8%
  • Fatigue 7%
More Oleptro side effects »

The desipramine FDA package insert doesn’t have numbers about how common side effects are.

More about desipramine side effects »
  • Drowsiness 3%
  • Headache 1%
  • Dizziness 4%
  • Allergic reactions 3%
  • Sinus infection 2%
  • Sore throat 2%
  • Dry mouth 2%
  • Lack of energy 2%
  • Back pain 1%
  • Diarrhea 1%
More Ambien side effects »
  • Drowsiness or fatigue 14%
  • Dry mouth 14%
  • Constipation 12%
  • Vision changes 7%
More amoxapine side effects »
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
How it works
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
Doxepin is a tricyclic antidepressant. It keeps norepinephrine and serotonin in your brain longer, helping you relax, and sleep. It also blocks the chemical that causes itch, and wakefulness.Prosom (estazolam) is a benzodiazepine. It helps you stay asleep by improving the quality of your sleep so you don't wake up as much at night.Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.Halcion (triazolam) is a benzodiazepine. It helps you stay asleep by extending how long you stay asleep, and improving the quality of your sleep so you don't wake up as much at night.Benadryl (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.Anafranil (Clomipramine) is a tricyclic antidepressant (TCA). It treats obsessive-compulsive disorder by affecting the levels of serotonin and norepinephrine in your brain.Dalmane (flurazepam) is a benzodiazepine. It activates the part of your brain for resting and digesting.Limbitrol (chlordiazepoxide / amitriptyline) is a combination of 2 medicines. Chlordiazepoxide is a benzodiazepine, and it calms activity in a part of the brain responsible for emotional responses. Amitriptyline is a tricyclic antidepressant, and it raises the amount of norepinephrine and serotonin in the brain, which can improve mood.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Norpramin (desipramine) is a tricyclic antidepressant. It increases the amount of norepinephrine and serotonin in the brain, two chemicals that regulate mood.Ambien (zolpidem) is in a class of drugs called sedative-hypnotics. It interacts with your brain to make you relaxed and sleepy.Asendin (amoxapine) is a tricyclic antidepressant. It increases the activity of serotonin and norepinephrine in your brain which regulate your mood.Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.
Type of medication
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
Prescription onlyPrescription onlyPrescription onlyPrescription or OTCPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Pill
  • Oral solution
  • Cream, gel, or ointment
  • Pill
  • Capsule
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Oral spray
  • Sublingual pill
  • Pill
  • Pill
  • Liquid
  • Injection
Used for
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
  • Alcoholism Anxiety Depression Anxiety Depression Anxiety Depression Psychoneurotic Personality Disorder Insomnia Pruritus Moderate
  • Anxiety And Depression
Risk factors for serious side effects
SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    Coming soon.
    • Using Prosom (estazolam) for more than 10 days
    • Drinking alcohol
    • Taking sedative medicines
    • People age 65 or older
    Detailed Prosom (estazolam) risks & warnings »
    • Taking more than the prescribed dose
    • Taking longer than 4 weeks
    • History of drug abuse
    • Long-term use
    • Women of childbearing age
    Detailed Restoril (temazepam) risks & warnings »
    • Using Halcion (triazolam) for more than 10 days
    • People age 65 or older
    • Drinking alcohol
    • Not allowing enough time for sleep
    Detailed Halcion (triazolam) risks & warnings »
    • Using other drugs with the same ingredients
    • Age 65 years or older
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Children age 6 years and younger
    Detailed Benadryl (diphenhydramine) risks & warnings »
    • Age 24 years or younger
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Using other medications that affect serotonin
    • History of seizure
    Detailed Anafranil (clomipramine) risks & warnings »
    • Alcohol
    • Taking narcotics, tranquilizers or antihistamines
    • Women
    • Over age 65
    Detailed Dalmane (flurazepam) risks & warnings »
    • People under age 24
    • Glaucoma
    • Heart disease
    • Alcohol
    • Taking narcotics, tranquilizers, or antihistamines
    Detailed Limbitrol (chlordiazepoxide / amitriptyline) risks & warnings »
    • Age 24 years or younger
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    Detailed Oleptro (trazodone) risks & warnings »
    • People under age 24
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    Detailed Norpramin (desipramine) risks & warnings »
    • Continuous use of Ambien (zolpidem) for 2 weeks or more
    • Alcohol
    • Taking other medications that make you less alert
    • Less than 8 hours of sleep.
    • Undiagnosed psychiatric conditions
    Detailed Ambien (zolpidem) risks & warnings »
    • People under age 24
    • Glaucoma
    • Taking antidepressants
    • Taking opioids for pain relief or medicines for anxiety
    • Over age 65
    Detailed Asendin (amoxapine) risks & warnings »
    • Taking with opioids
    • Taking more than the prescribed dose
    • Taking Ativan (lorazepam) for longer than 4 weeks
    • History of drug abuse
    • Long-term use
    Detailed Ativan (lorazepam) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
    • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
    Alcohol
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    • It is not safe to drink alcohol while taking this.
    • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
    • Don't take it with alcohol or other drugs that make you sleepy.
    No alcohol related info.
    • Can be dangerous if combined with alcohol or narcotics.
    • Don't drink alcohol or take narcotics, tranquilizers, or antihistamines if you're taking Limbitrol (chlordiazepoxide / amitriptyline). This can slow down your breathing. Talk to your doctor if this is a problem.
    • Don't drink alcohol or take any narcotics while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can slow your breathing.
    No alcohol related info.No alcohol related info.
    • Avoid alcohol and drugs when taking Ambien (zolpidem).
    No alcohol related info.
    • Not safe to use with alcohol.
    • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
    Food
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    No food related info.No food related info.No food related info.No food related info.No food related info.
    • Take it with food and/or at bedtime to decrease the potential side effects.
    No food related info.No food related info.No food related info.No food related info.No food related info.
    • Take Asendin (amoxapine) with food to avoid stomach upset.
    No food related info.
    Kidneys and liver
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
    • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
    No kidneys and liver related info.No kidneys and liver related info.
    Sleep
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    No sleep related info.No sleep related info.
    • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • People taking Halcion (triazolam) for sleep while fighting jet lag have reported not being able to remember what happened a few hours after taking the medicine. This is more likely to happen if you drink alcohol, or if you don't have enough time to sleep. Give yourself at least 7 to 8 hours to sleep to stop this from happening.
    • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
    • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
    • Can help you sleep.
    • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
    • People taking Dalmane (flurazepam) for sleep have reported having difficulty concentrating the next day, and have problems driving or operating machinery. Talk to your doctor if this is a problem.
    • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
    • Limbitrol (chlordiazepoxide / amitriptyline) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how it affects you. This can be worse if you drink alcohol or take narcotics.
    No sleep related info.No sleep related info.
    • Ambien (zolpidem) makes you feel drowsy and sleepy, potentially leading to falls and severe injuries. This is especially a risk if you're older. Falls from sleep medicines like Ambien (zolpidem) have caused severe injuries such as hip fractures and head injury. You may need a lower dose if you're taking other medications that also cause drowsiness. Check with your doctor first.
    • Only take it if you have time to sleep for at least 8 hours.
    • Effective at helping people fall asleep faster and sleep longer.
    • You can feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    • Can cause temporary dizziness and drowsiness.
    • Can cause memory problems, drowsiness, dizziness, and confusion.
    Weight
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • Doxepin can increase your appetite, leading to weight gain.
    No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.
    Upsides and benefits
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • In a clinical trial Doxepin was able to significantly improve sleep quality.
    • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
    • Once your body gets used to Doxepin, most of the side effects go away.
    • Doxepin comes in a generic form, so it is pretty cheap.
    • Doxepin is not addictive.
    • Prosom (estazolam) is available in generic.
    • Helps you fall asleep and stay asleep.
    • Can be helpful to reduce anxiety.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • Halcion (triazolam) is available as a generic.
    • Compared to other similar medicines, you're less likely to have a hangover effect from Halcion (triazolam) the next day.
    • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
    • It can provide quick relief of allergy symptoms for both kids and adults.
    • It makes you sleepy, so it'll help if your allergies are bothering you at night.
    • The effects wear off in 4 to 6 hours, so side effects don't last that long.
    • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
    • Works well to decrease the symptoms of obsessive-compulsive disorder (OCD).
    • Helps some people see improvements in their mood.
    • Can help you sleep.
    • Lower risk of causing heart problems compared to other medicine in this class.
    • Dalmane (flurazepam) works 15-30 minutes after taking it.
    • Dalmane (flurazepam) is available in generic.
    • Limbitrol (chlordiazepoxide / amitriptyline) is available as a generic.
    • Limbitrol (chlordiazepoxide / amitriptyline) works faster than amitriptyline alone.
    • Commonly used in lower doses to help treat sleep problems (insomnia).
    • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
    • Fewer sexual side effects than many other antidepressants.
    • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
    • Comes as a generic medication and is cheaper than many other sleep aides.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
    • Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
    • Effective at helping people fall asleep faster and sleep longer.
    • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
    • Generic is available.
    • Asendin (amoxapine) can be used to treat more severe forms of depression.
    • Compared to similar medicines, Asendin (amoxapine) improves the mood in depression more quickly.
    • Asendin (amoxapine) is available as generic.
    • Effective at relieving short-term anxiety.
    • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
    • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
    Downsides and risks
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
    • Doxepin can increase your appetite, leading to weight gain.
    • Taking Doxepin can make emptying your bladder difficult.
    • Some people have suicidal thoughts when taking Doxepin.
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    • Prosom (estazolam) isn't recommended if you're age 65 or older because the side effects can be more intense.
    • You can become dependent on Prosom (estazolam) if you take it for more than a few weeks.
    • If you stop Prosom (estazolam) suddenly after taking it for a while, your insomnia might come back even worse than when you started.
    • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
    • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
    • It's not recommended for people age 65 years or older.
    • Can't be used by pregnant women since it'll cause harm to the baby.
    • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
    • Your body can get used to Halcion (triazolam) after 2 weeks.
    • Stopping Halcion (triazolam) suddenly can make your insomnia worse. Talk to your doctor if you want to stop taking it.
    • People who take Halcion (triazolam) can have more anxiety during the day.
    • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
    • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
    • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
    • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
    • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
    • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
    • Can cause sexual performance problems in men.
    • Increases the risk of falls, especially when used in the elderly.
    • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
    • Should only be used short-term because it can be addicting.
    • Can cause sleep-walking or other sleep-related activities that you may not remember doing the next day.
    • Limbitrol (chlordiazepoxide / amitriptyline) is only available in certain strengths, so it can be difficult to customize a dose that treats both anxiety and depression.
    • Limbitrol (chlordiazepoxide / amitriptyline) contains chlordiazepoxide, which can be potentially addicting.
    • You might not notice any changes in your mood until you've been taking Limbitrol (chlordiazepoxide / amitriptyline) for several weeks.
    • Amitriptyline alone is considered a better treatment for anxiety and depression than Limbitrol (chlordiazepoxide / amitriptyline).
    • Other medicines are considered first choice for treating anxiety and depression over Limbitrol (chlordiazepoxide / amitriptyline).
    • Not as effective as other medications for depression.
    • More sedating than other antidepressants.
    • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
    • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
    • Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
    • In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
    • If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
    • Not recommended in children under 12 years of age.
    • Not typically used for long-term treatment because it can be habit-forming.
    • Some people find that Ambien (zolpidem) becomes less effective over time.
    • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
    • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
    • Asendin (amoxapine) is not a first choice medicine for depression because of side effects.
    • In some people, Asendin (amoxapine) can stop working as early as 2-3 months after you start taking it.
    • Not recommended in older people, children under 16, or people who've had a history of seizures.
    • Can cause memory problems, drowsiness, dizziness, and confusion.
    • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
    • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
    • Most people find that Ativan (lorazepam) gets less effective over time.
    Tips from our pharmacists for people taking the medication
    SilenorEstazolamRestoriltriazolamBenadrylAnafranilDalmanechlordiazepoxide / amitriptylineOleptrodesipramineAmbienamoxapineAtivan
    • Take Doxepin 30 minutes before bedtime so it starts working when you get in bed.
    • Avoid activities that need you to be fully alert like driving, until you know how Doxepin affects you.
    • Follow up with your doctor so he or she can make sure Doxepin is the right medication for your depression.
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    • Some people get dry mouth, or constipation when taking Doxepin. Sugar free gum or candy can help the dry mouth, and drinking more fluid can help with constipation.
    • Avoid direct sunlight while taking this medication. When you can’t avoid it, be sure to use sunscreen. It’s also important to put on a long-sleeved shirt, pants, hat, and sunglasses.
    • Don't take Prosom (estazolam) unless you know you'll be going to sleep right away.
    • Make sure you can sleep for at least 8 hours before you take it.
    • Prosom (estazolam) works best if you develop good sleeping habits.
    • Take Prosom (estazolam) for the shortest amount of time needed to treat your insomnia since it can be addicting.
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    • Use only as needed when you can't sleep.
    • Starts working within 45 minutes.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Take it only if you can get a full night's rest.
    • It is not safe to drink alcohol while taking this.
    • Tell your doctor if you notice any changes to your memory or mood.
    • Take Halcion (triazolam) on an empty stomach; otherwise, it won't work as well.
    • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
    • You should only use Halcion (triazolam) for 7 to10 days. If it doesn't help you sleep, talk to your doctor.
    • You might have a hangover-like feeling the next day after taking Halcion (triazolam). Be careful driving or doing anything requiring concentration until you know how your body reacts to it.
    • Only take Halcion (triazolam) if you know you're going to bed right away.
    • Take it as needed every 4 to 6 hours.
    • Benadryl (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
    • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
    • Don't take it with alcohol or other drugs that make you sleepy.
    • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
    • If you only have itchy or watery eyes, try using just an antihistamine eye drop.
    • Needs to be taken every day for 2 to 3 weeks to see the full effect of the medication.
    • It's important to keep taking Anafranil (Clomipramine) even when you feel your symptoms are getting better.
    • Take it with food and/or at bedtime to decrease the potential side effects.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • If you decide to stop taking Anafranil (Clomipramine), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
    • Can be dangerous if combined with alcohol or narcotics.
    • Effect lasts long and may carry into the next morning. Take Dalmane (flurazepam) only if you expect to be in bed for full 7-8 hours.
    • Can cause rebound insomnia if you stop taking it, especially if you've been on it for a while.
    • Can cause sleep walking or doing other behaviors while asleep. Talk to your doctor right away if this happens.
    • Don't drink alcohol or take any narcotics while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can slow your breathing.
    • If you've taken Limbitrol (chlordiazepoxide / amitriptyline) for an extended amount of time, don't stop taking it suddenly without talking to your doctor first. It can be very dangerous.
    • Don't drive or do anything requiring concentration while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can make you sleepy. This can be worse if you drink alcohol or take narcotics.
    • You might not notice changes in your mood until you've taken Limbitrol (chlordiazepoxide / amitriptyline) for at least a few weeks.
    • If you're being switched to Limbitrol (chlordiazepoxide / amitriptyline) from a group of medicines called monoamine oxidase inhibitors (MAOI), you should wait at least 14 days before you start.
    • Makes you sleepy. Take at bedtime.
    • Can cause temporary dry mouth and upset stomach.
    • Seek medical attention for unwanted, persistent erection.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Don't drive or do anything requiring concentration until you know how Norpramin (desipramine) affects you since it can make you feel sleepy.
    • Talk to your doctor right away if your mood suddenly darkens and you want to hurt yourself while taking Norpramin (desipramine).
    • If you're being switched to Norpramin (desipramine) from monoamine oxidase inhibitors, you'll need to wait 2 weeks before you can start it.
    • Don't stop taking Norpramin (desipramine) suddenly without talking to your doctor first.
    • Take 30 to 45 minutes before bedtime.
    • Only take it if you have time to sleep for at least 8 hours.
    • Can be addictive. Meant for short-term treatment. Dependence can form after daily use for 2 weeks.
    • Avoid alcohol and drugs when taking Ambien (zolpidem).
    • Withdrawal symptoms can occur if you abruptly stop the drug and you've been regularly using it. The symptoms usually resolve in 1 to 2 nights.
    • Report any confusion or changes in thoughts or behavior.
    • You can feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    • You might not notice any changes in your mood for at least a few weeks.
    • Take Asendin (amoxapine) with food to avoid stomach upset.
    • You're more likely to be dehydrated and constipated. Drink plenty of fluids and be careful not to get overheated if you're out in the sun.
    • Don't stop taking Asendin (amoxapine) without talking to your doctor. Stopping Asendin (amoxapine) suddenly can be very dangerous.
    • Can cause temporary dizziness and drowsiness.
    • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
    • Not safe to use with alcohol.
    • Use caution or avoid use in older adults.
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