Prescription onlyLower-cost generic available

Zocor Alternatives

(Simvastatin)

Prescription onlyLower-cost generic available
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Compare Zocor (Simvastatin) to alternatives

These medications are comparable to Zocor (Simvastatin) or used for similar purposes.

Zocor
(Simvastatin)

Zetia
(Ezetimibe)

Pravachol
(Pravastatin)

Mevacor
(Lovastatin)

Antara
(Fenofibrate)

Niaspan
(Niacin)

Trilipix
(Fenofibric Acid)

Vytorin
(Ezetimibe / Simvastatin)

Lipitor
(Atorvastatin)

Crestor
(Rosuvastatin)

Lowers cholesterol. Zocor (Simvastatin) is a good medication to improve your cholesterol. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.Lowers cholesterol. Pravachol (Pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. niacin is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.Lowers cholesterol. Vytorin is expensive and is no more effective than simvastatin by itself.Lowers cholesterol. Lipitor (Atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.Lowers cholesterol. Crestor (Rosuvastatin) is one of the most effective statins to improve cholesterol, but the brand name medication is expensive. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.13Simvastatin
Reviews for Zocor (Simvastatin)
61%
of people (All ages) say Zocor (Simvastatin) is worth it
48%
say it works well
14%
say it's a big hassle
1176 reviews
Have you used Zocor (Simvastatin)?
Worth itNot sureNot worth it
Reviews for Zetia (Ezetimibe)
42%
19% vs. Zocor (Simvastatin)
34%
14% vs. Zocor (Simvastatin)
21%
7% vs. Zocor (Simvastatin)
128 reviews
Have you used Zetia (Ezetimibe)?
Worth itNot sureNot worth it
Reviews for Pravachol (Pravastatin)
54%
7% vs. Zocor (Simvastatin)
44%
4% vs. Zocor (Simvastatin)
19%
5% vs. Zocor (Simvastatin)
426 reviews
Have you used Pravachol (Pravastatin)?
Worth itNot sureNot worth it
Reviews for Mevacor (Lovastatin)
43%
18% vs. Zocor (Simvastatin)
39%
9% vs. Zocor (Simvastatin)
22%
8% vs. Zocor (Simvastatin)
Have you used Mevacor (Lovastatin)?
Worth itNot sureNot worth it
Reviews for Antara (Fenofibrate)
27%
34% vs. Zocor (Simvastatin)
14%
34% vs. Zocor (Simvastatin)
29%
15% vs. Zocor (Simvastatin)
Have you used Antara (Fenofibrate)?
Worth itNot sureNot worth it
Reviews for Niaspan (Niacin)
43%
18% vs. Zocor (Simvastatin)
31%
17% vs. Zocor (Simvastatin)
19%
5% vs. Zocor (Simvastatin)
380 reviews
Have you used Niaspan (Niacin)?
Worth itNot sureNot worth it
Reviews for Trilipix (Fenofibric Acid)
50%
11% vs. Zocor (Simvastatin)
22%
26% vs. Zocor (Simvastatin)
25%
11% vs. Zocor (Simvastatin)
Have you used Trilipix (Fenofibric Acid)?
Worth itNot sureNot worth it
Reviews for Vytorin (Ezetimibe / Simvastatin)
53%
8% vs. Zocor (Simvastatin)
36%
12% vs. Zocor (Simvastatin)
19%
5% vs. Zocor (Simvastatin)
Have you used Vytorin (Ezetimibe / Simvastatin)?
Worth itNot sureNot worth it
Reviews for Lipitor (Atorvastatin)
63%
+2% vs. Zocor (Simvastatin)
51%
+3% vs. Zocor (Simvastatin)
13%
+1% vs. Zocor (Simvastatin)
1377 reviews
Have you used Lipitor (Atorvastatin)?
Worth itNot sureNot worth it
Reviews for Crestor (Rosuvastatin)
60%
1% vs. Zocor (Simvastatin)
47%
1% vs. Zocor (Simvastatin)
15%
1% vs. Zocor (Simvastatin)
751 reviews
Have you used Crestor (Rosuvastatin)?
Worth itNot sureNot worth it
Side effects
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor

The Simvastatin FDA package insert doesn’t have numbers about how common side effects are.

More about Simvastatin side effects »

The Zetia FDA package insert doesn’t have numbers about how common side effects are.

More about Zetia side effects »
  • Rash 6%
  • Upper respiratory infection 4%
  • Nausea/vomiting 4%
  • Diarrhea 3%
  • Flu 3%
  • Decreased liver functiond 3%
  • Headache 3%
  • Heart-related chest pain 2%
  • Sore throats 2%
  • Inflammation inside the noses 2%
More Pravastatin side effects »
  • Constipation 2%
  • Passing gas 1%
  • Muscle weakness 1%
  • Abdominal pain 1%
  • Diarrhea 1%
  • Muscle pain 1%
More Lovastatin side effects »
  • Abnormal liver function tests 7%
  • Increased ast 2%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
  • Constipation 1%
  • Increased alt 1%
More Antara side effects »
  • Flushing 50%
  • Itching 6%
  • Vomiting 5%
  • Nausea 4%
  • Cough increased 2%
  • Diarrhea 1%
More Niaspan side effects »
  • Abnormal liver tests 7%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
More Trilipix side effects »
  • Unexplained muscle pain or weakness 1%
More Vytorin side effects »
  • Diarrhea 8%
  • Common cold 5%
  • Muscle pain 5%
  • Joint pain 5%
  • Nausea 3%
  • Pain in the arms and legs 3%
  • Urinary tract infection 2%
  • Muscle spasms 2%
  • Sleep difficulty 2%
  • Sore throat 2%
More Atorvastatin side effects »
  • Headache 4%
  • Constipation 3%
  • Joint pain 3%
  • Nausea 3%
  • Muscle weakness 2%
  • Muscle pain 1%
  • Dizziness 1%
  • Diabetes mellitus 1%
More Crestor side effects »
How it works
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
Zocor (Simvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.Pravachol (Pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).niacin is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it seems to lower the amount of "bad" cholesterol (LDL) made by the liver. It may also help your body process cholesterol.Trilipix is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Vytorin is a combination cholesterol-lowering medicine. Simvastatin prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). Ezetimibe prevents cholesterol absorption in your intestines.Lipitor (Atorvastatin) is a cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Crestor (Rosuvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
Cholesterol-lowering
Statin
Prescription only
Cholesterol-lowering
Cholesterol inhibitor
Prescription only
Cholesterol-lowering
Statin
Prescription only
Cholesterol-lowering
Statin
Prescription only
Cholesterol-lowering
Fibric acid
Prescription only
Cholesterol-lowering
Nicotinic acid
Prescription only
Cholesterol-lowering
Fibric acid
Prescription only
Cholesterol-lowering
Cholesterol inhibitor
Statin
Prescription only
Cholesterol-lowering
Statin
Prescription only
Cholesterol-lowering
Statin
Prescription only
Available as
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Pill
  • Dissolving tablet
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
Used for (click to learn more)
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
Risk factors for serious side effects
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Kidney disease
  • High dose of Zocor (Simvastatin)
  • Combining Zocor (Simvastatin) with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
Detailed risks & warnings »
  • Taking Zetia (Ezetimibe) with statins
  • Past history of liver disease
Detailed risks & warnings »
  • Kidney disease
  • High dose of Pravachol (Pravastatin)
  • Combining Pravachol (Pravastatin) with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
Detailed risks & warnings »
  • Kidney disease
  • High dose of Mevacor (Lovastatin)
  • Combining with certain cholesterol-lowering drugs
  • Older age and female gender
  • Heavy alcohol use
Detailed risks & warnings »
  • Taking Antara (Fenofibrate) with statins
  • Past history of liver disease
  • Taking Antara (Fenofibrate) with anticoagulants
Detailed risks & warnings »
  • Taking Niaspan (Niacin) with statins
  • Heavy alcohol use
  • Past history of liver disease
  • Diabetes
  • Taking Niaspan (Niacin) with anticoagulants
Detailed risks & warnings »
  • Taking Trilipix (Fenofibric Acid) with statins
  • Past history of liver disease
  • Taking Trilipix (Fenofibric Acid) with anticoagulants
Detailed risks & warnings »
  • Asian patients taking high-dose niacin
  • Past history of liver disease
  • heavy alcohol use
  • Diabetes
  • Pregnancy
Detailed risks & warnings »
  • Heavy alcohol use
  • Prior history of chronic liver disease
  • Pregnancy
  • History of hemorrhagic strokes
Detailed risks & warnings »
  • Heavy alcohol use
  • Prior history of chronic liver disease
  • Pregnancy
Detailed risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Interactions
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
No interactions related info.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
Alcohol
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
No alcohol related info.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
  • Don't drink a lot of alcohol while taking this medicine.
  • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
No alcohol related info.No alcohol related info.
  • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
Food
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
No food related info.No food related info.No food related info.
  • Works best if you take it once a day after your evening meal.
No food related info.
  • You have to take it before bedtime with a low-fat snack.
  • Take it at bedtime with a low-fat snack.
  • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
No food related info.No food related info.No food related info.No food related info.
Kidneys and liver
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • There are rare cases of muscle damage leading to kidney failure in people taking Zocor (Simvastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
  • There are reports of liver damage in people who take Zocor (Simvastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
  • Reports of liver disease have been reported in people who take Zetia (Ezetimibe), especially if taken with statins. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • There are rare cases of muscle damage leading to kidney failure in people taking Pravachol (Pravastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
  • There are reports of liver damage in people who take Pravachol (Pravastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
  • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
  • Reports of liver damage have been reported in people who take Antara (Fenofibrate), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
No kidneys and liver related info.
  • Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
  • People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.
  • Statins such as Lipitor (Atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
  • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (Atorvastatin).
  • People on Lipitor (Atorvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you're older and you're taking higher doses of Lipitor (Atorvastatin). If you suddenly feel muscle pain or weakness and you haven't been exercising, stop taking Lipitor (Atorvastatin) and talk to your doctor right away.
  • Liver damage has been reported in people who take Lipitor (Atorvastatin). If you notice dark urine or yellowing of your eyes or skin, talk to your doctor. Your doctor might run blood tests to check your liver.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • People on Crestor (Rosuvastatin) have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
  • Liver damage has been reported in people who take Crestor (Rosuvastatin). If you notice dark urine or yellowing of the eyes or skin, talk to your doctor. Your doctor may monitor your liver periodically.
Pain
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
No pain related info.
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
  • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
No pain related info.
  • Can cause flushing and stomach pain or discomfort.
No pain related info.No pain related info.
  • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
No pain related info.
Upsides and benefits
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers the risk of a second heart attack.
  • Good for lowering triglycerides (fats).
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lipitor (Atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • It's one of the strongest cholesterol-lowering statin medications.
  • Lipitor (Atorvastatin) is a good option for people who have high cholesterol and diabetes.
  • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
  • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as hardening of the arteries.
  • In clinical studies, Crestor has the strongest effect on lowering "bad" cholesterol compared to other statins.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
Downsides and risks
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, Zetia is not as effective as statins for improving cholesterol.
  • There's no generic available, so it can be expensive.
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Not the best choice for people who have very high cholesterol levels.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • In studies, it didn't lower heart disease in people with Type 2 diabetes.
  • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
  • Different forms and strengths of this medication can't be substituted for each other.
  • By itself, niacin is not as effective as statins for improving cholesterol.
  • Can cause flushing and stomach pain or discomfort.
  • You have to take it before bedtime with a low-fat snack.
  • If you don't take it regularly, you might have to re-start the medicine at a lower dose.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • Statins such as Lipitor (Atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
  • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (Atorvastatin).
  • Even with a generic available in 2016, can be expensive.
  • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
  • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
SimvastatinZetiaPravastatinLovastatinAntaraNiaspanTrilipixVytorinAtorvastatinCrestor
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
  • Lowers bad cholesterol, and raises good cholesterol.
  • Tell your doctor if you develop bone or muscle pain.
  • Can be used with other medications to lower cholesterol.
  • May cause diarrhea or raise your chance of getting colds.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
  • Works best if you take it once a day after your evening meal.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Most people reach their target cholesterol levels in 4 to 6 weeks.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
  • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
  • Can cause backache or headache.
  • Don't drink a lot of alcohol while taking this medicine.
  • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
  • You should use this medicine in combination with a healthy diet.
  • Lowers triglycerides.
  • Call your doctor if you develop muscle or abdominal pain.
  • Take it at bedtime with a low-fat snack.
  • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
  • Can cause flushing.
  • Don't stop taking this medicine suddenly.
  • Call your doctor if you develop muscle pain.
  • Can be used with other medications to help lower cholesterol.
  • Can raise your chance of getting colds and flu.
  • Lowers triglycerides.
  • Call your doctor if you develop muscle or abdominal pain.
  • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
  • Take it in the evening.
  • Can cause headaches or diarrhea.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Call your doctor if you develop muscle pain.
  • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
  • Don't eat grapefruit or drink grapefruit juice while taking this medicine.
  • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
  • Also tell your doctor if you have dark urine or if you notice a yellow tint in your eyes or skin.
  • Lipitor (Atorvastatin) isn't safe to use if you're pregnant.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Don't take antacids for at least 2 hours before and after taking this medicine.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
Learn more
More about SimvastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zocor (Simvastatin)?
Worth itNot sureNot worth it
More about ZetiaSide effectsReviews & ratingsFDA package insert
Have you used Zetia (Ezetimibe)?
Worth itNot sureNot worth it
More about PravastatinSide effectsReviews & ratingsFDA package insert
Have you used Pravachol (Pravastatin)?
Worth itNot sureNot worth it
More about LovastatinSide effectsReviews & ratingsFDA package insert
Have you used Mevacor (Lovastatin)?
Worth itNot sureNot worth it
More about AntaraSide effectsReviews & ratingsFDA package insert
Have you used Antara (Fenofibrate)?
Worth itNot sureNot worth it
More about NiaspanSide effectsReviews & ratingsFDA package insert
Have you used Niaspan (Niacin)?
Worth itNot sureNot worth it
More about TrilipixSide effectsReviews & ratingsFDA package insert
Have you used Trilipix (Fenofibric Acid)?
Worth itNot sureNot worth it
More about VytorinSide effectsReviews & ratingsFDA package insert
Have you used Vytorin (Ezetimibe / Simvastatin)?
Worth itNot sureNot worth it
More about AtorvastatinSide effectsReviews & ratingsFDA package insert
Have you used Lipitor (Atorvastatin)?
Worth itNot sureNot worth it
More about CrestorSide effectsReviews & ratingsFDA package insert
Have you used Crestor (Rosuvastatin)?
Worth itNot sureNot worth it