Sovaldi

(sofosbuvir)

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Treats hepatitis C infection.

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Our bottom line

Sovaldi (sofosbuvir) is an effective medicine to treat chronic hepatitis C infection, but it must be used with other antiviral medicines.

Quick facts about Sovaldi
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 28 400mg tablets
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$28567.00

Upsides

  • Most people who use Sovaldi (sofosbuvir) have good results, and often find no traces of the hepatitis C infection in their blood three months later.
  • This treatment works well for people who have hepatitis C and HIV, liver cancer, or who are waiting for a liver transplant.
  • Sovaldi (sofosbuvir) is only taken once a day.
  • Sovaldi (sofosbuvir) has fewer side effects than other medications used to treat this infection.

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What to expect from Sovaldi, on one page

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Downsides

  • There's no generic available, so it can be very expensive.
  • Must be used with other antiviral medicines, such as ribavirin and/or peginterferon alfa.
  • Sovaldi (sofosbuvir) doesn't treat all 6 types of hepatitis C.
  • This medicine isn't the best choice if you have kidney problems.

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Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Sovaldi, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 28 400mg tablets
Determining your location...
$28567.00
How it works

Sovaldi (sofosbuvir) is an antiviral medicine. It stops the hepatitis C virus (HCV) from multiplying in your body.

Quick facts about Sovaldi
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
Tried Sovaldi? Write a review!

What to expect when you take Sovaldi (sofosbuvir) for Hepatitis C

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Side effect rates for Sovaldi (sofosbuvir)

From 721 clinical trials of Sovaldi when taken for hepatitis c
  • Fatigue
  • Headache
  • Fatigue
  • Headache
  • Nausea
  • Fatigue
  • Headache
  • Nausea
  • Difficulty sleeping
  • Itchy skin

Risks and Warnings for Sovaldi (sofosbuvir)

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    • Higher risk if:
    • History of or active hepatitis B infection

    If you've had hepatitis B in the past, or currently have it, Sovaldi (sofosbuvir) can make it come back or get worse. Before you start using Sovaldi (sofosbuvir), you'll need to be tested for hepatitis B. Tell your doctor if you've ever had hepatitis B or have been treated for it in the past.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Sovaldi (sofosbuvir)

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Interactions
  • Sovaldi (sofosbuvir) can interact with many medicines and cause serious or life-threatening side effects. Talk to your doctor or pharmacist about your current medicines and make sure they know if you'll be starting or stopping any new prescription medicines, vitamins, or supplements.
  • There are many interactions between Sovaldi (sofosbuvir) and other medicines and herbal supplements, so talk to your doctor or pharmacist before starting anything new.
Kidneys and liver
  • Depending on your type of hepatitis C infection, you'll take Sovaldi (sofosbuvir) for either 12 weeks or 24 weeks. Don't stop using it early or make any other changes without first talking to your doctor or pharmacist.
  • Sovaldi (sofosbuvir) doesn't treat all 6 types of hepatitis C.
  • This medicine isn't the best choice if you have kidney problems.