Prescription onlyNo lower cost generic available



Prescription onlyNo lower cost generic available
  • Inhaler
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Makes it easier to breathe.

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Our bottom line

Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.

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  • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
  • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
  • You only need to take it once a day.
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  • Won't cure your COPD (but it will relieve your symptoms).
  • You'll need to use this medicine for a long time, and you have to take it every day.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
  • You might feel dizzy or have blurry vision while taking this medicine.
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Side effect rates for Spiriva (Tiotropium)

921 From clinical trials of Spiriva / COPD (18 mcg)
  • Respiratory tract infection
  • Dry mouth
  • Sore throat
  • Sinus inflammation
  • Sore throat
  • Sinus inflammation
  • Urinary tract infection
  • Chest pain (non-specific)
  • Headache
  • Inflammation inside the nose

Risks and Warnings for Spiriva (Tiotropium)

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    • Higher risk if:
    • History of atropine allergic reaction

    There are reports of severe allergic reactions in people taking Spiriva (Tiotropium) with a history of atropine allergy. Spiriva (Tiotropium) has a similar chemical structure to atropine so if you've had an allergic reaction to atropine, there is a possibility you will be allergic to Spiriva (Tiotropium). Call 911 or your doctor right away if you develop severe rash, itching, swelling or difficulty breathing while taking Spiriva (Tiotropium). Talk to your doctor about other medication choices to treat your COPD if you know you have an allergy to the drug atropine.

Common concerns from people taking Spiriva (Tiotropium)

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Kidneys and liver
  • The kidney is mainly responsible for removing Spiriva (Tiotropium) from the body so people with kidney disease or reduced function need to be watched closely. Spiriva (Tiotropium) can build up in the body and cause certain side effects. Tell your doctor if you develop dry mouth, blurry vision, confusion, sweating, increased heart rate or constipation. You may need to discuss other medication options to treat your COPD.