Prescription onlyClass: Respiratory

Spiriva Alternatives

(Tiotropium)

Prescription onlyClass: Respiratory
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Compare Spiriva (Tiotropium) to alternatives

These medications are comparable to Spiriva (Tiotropium) or used for similar purposes.

Spiriva
(Tiotropium)

Advair Diskus
(Fluticasone / Salmeterol)

Atrovent
(Ipratropium)

Combivent
(Ipratropium / Albuterol)

Dulera
(Mometasone / Formoterol)

Symbicort
(Budesonide / Formoterol)

Theo-24
(Theophylline)

Theo-24
(Theophylline)

Makes it easier to breathe. Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.Prevents breathing problems. Advair Diskus (Fluticasone / Salmeterol) is good for people who need two medicines to control their asthma or COPD, but it might be expensive since there's no generic available.Coming soon.Makes it easier to breathe. Combivent (Ipratropium / Albuterol) is good for people who need 2 medicines to relieve their COPD symptoms, but you need to be okay with taking it four times a day.Prevents breathing problems. Dulera (Mometasone / Formoterol) is a convenient medication that'll control your asthma long-term, but it won’t stop a sudden asthma attack.Prevents breathing problems. Symbicort (Budesonide / Formoterol) is good for people who need two medicines to control their asthma or COPD, but it might be expensive since there's no generic available.Coming soon.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.78Spiriva
Reviews for Spiriva (Tiotropium)
64%
of people (All ages) say Spiriva (Tiotropium) is worth it
46%
say it works well
8%
say it's a big hassle
Have you used Spiriva (Tiotropium)?
Worth itNot sureNot worth it
Reviews for Advair Diskus (Fluticasone / Salmeterol)
66%
+2% better vs. Spiriva (Tiotropium)
48%
+2% better vs. Spiriva (Tiotropium)
11%
-3% worse vs. Spiriva (Tiotropium)
799 reviews
Have you used Advair Diskus (Fluticasone / Salmeterol)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Atrovent (Ipratropium)?
Worth itNot sureNot worth it
Reviews for Combivent (Ipratropium / Albuterol)
63%
-1% worse vs. Spiriva (Tiotropium)
37%
-9% worse vs. Spiriva (Tiotropium)
13%
-5% worse vs. Spiriva (Tiotropium)
142 reviews
Have you used Combivent (Ipratropium / Albuterol)?
Worth itNot sureNot worth it
Reviews for Dulera (Mometasone / Formoterol)
84%
+20% better vs. Spiriva (Tiotropium)
79%
+33% better vs. Spiriva (Tiotropium)
8%
Same vs. Spiriva (Tiotropium)
Have you used Dulera (Mometasone / Formoterol)?
Worth itNot sureNot worth it
Reviews for Symbicort (Budesonide / Formoterol)
58%
-6% worse vs. Spiriva (Tiotropium)
40%
-6% worse vs. Spiriva (Tiotropium)
14%
-6% worse vs. Spiriva (Tiotropium)
394 reviews
Have you used Symbicort (Budesonide / Formoterol)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Theo-24 (Theophylline)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Theo-24 (Theophylline)?
Worth itNot sureNot worth it
Side effects
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
  • Respiratory tract infection 4%
  • Dry mouth 13%
  • Sore throat 2%
  • Sinus inflammation 2%
  • Urinary tract infection 2%
  • Chest pain (non-specific) 2%
  • Headache 1%
  • Indigestion 1%
More Spiriva side effects »
  • Lung infection 6%
  • Headaches 4%
  • Candidiasis mouth/throat 9%
  • Throat irritation 1%
  • Viral respiratory infections 3%
  • Hoarseness/dysphonia 5%
  • Dizziness 2%
  • Fever 1%
More Advair side effects »

We haven’t found good data for Atrovent side effects.

FDA side effect reports for Atrovent »
  • Bronchitis 12%
  • Ear, nose, or throat infection 11%
  • Headache 6%
  • Shortness of breath 5%
  • Coughing 4%
  • Pain 3%
  • Respiratory disorders 3%
  • Nausea 2%
  • Sore throat 2%
  • Sinus inflammation 2%
More Combivent side effects »
  • Common cold 1%
  • Headache 1%
  • Speech disorder 5%
  • Sinus inflammation 2%
More Dulera side effects »
  • Common cold 2%
  • Throat pain 1%
  • Sinus inflammation 1%
  • Flu 2%
  • Back pain 2%
  • Nasal congestion 2%
  • Stomach discomfort 5%
  • Vomiting 2%
More Symbicort side effects »

We haven’t found good data for Theophylline side effects.

FDA side effect reports for Theophylline »

We haven’t found good data for Theophylline side effects.

FDA side effect reports for Theophylline »
How it works
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
Spiriva (Tiotropium) is a bronchodilator. It relaxes muscles in your lungs to open your airways and make breathing easier.Advair Diskus (Fluticasone / Salmeterol) is a combination medicine. Fluticasone (a corticosteroid) lowers lung inflammation to control asthma and COPD. Salmeterol (a bronchodilator) relaxes muscles in your lungs to open airways and make breathing easier.Coming soon.Combivent (Ipratropium / Albuterol) is a combination medicine. It contains two bronchodilators (ipratropium and albuterol), which relax muscles in your lungs to open airways and make breathing easier.Dulera (Mometasone / Formoterol) is a combination asthma medicine. Mometasone (a corticosteroid) lowers lung inflammation and works to control your asthma and prevent asthma attacks. Formoterol (a long-acting bronchodilator) relaxes muscles in your lungs to open airways and prevent wheezing and shortness of breath.Symbicort (Budesonide / Formoterol) is a combination medicine. Budesonide (a corticosteroid) lowers lung inflammation to control asthma and COPD. Formoterol (a bronchodilator) relaxes muscles in your lungs to open airways and make breathing easier.Coming soon.Coming soon.
Type of medication
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
  • Inhaler
  • Inhaler
  • Inhaler
  • Inhaler
  • Inhaler
  • Inhaler
  • Pill
  • Extended release
  • Liquid
Used for
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
  • Chronic Obstructive Pulmonary Disease Nasal Discharge
  • Asthma Chronic Obstructive Pulmonary Disease Exercise Induced Asthma Prophylaxis Nocturnal Asthma
  • Asthma Chronic Obstructive Pulmonary Disease Exercise Induced Asthma Prophylaxis Nocturnal Asthma
Risk factors for serious side effects
SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
  • History of atropine allergic reaction
    • History of narrow-angle glaucoma
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
    • History of moderate to severe kidney disease
    • Taking with other anticholinergic medications
    Detailed Spiriva (Tiotropium) risks & warnings »
    • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.
    • History of chronic obstructive pulmonary disease (COPD)
    • COPD includes chronic bronchitis and emphysema
    • Age greater than 65 years
    • Lowering dose or stopping Advair Diskus (Fluticasone / Salmeterol) too quickly especially after long-term treatment
    • Stress such as trauma, surgery or infection
    • Not rinsing mouth after use
    • Higher dose of the corticosteroid medication contained in Advair Diskus (Fluticasone / Salmeterol)
    • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.
    • History of arrhythmia, hypertension or heart failure
    • Severe milk protein allergy
    Detailed Advair Diskus (Fluticasone / Salmeterol) risks & warnings »
    Coming soon.
      • History of rapid heartbeat
      • History of high blood pressure
      • history of heart failure or chest pain.
      • History of narrow-angle glaucoma
      • History of high eye pressure
      • Spraying Combivent (Ipratropium / Albuterol) into eyes
      • History of urinary bladder blockage (urinary obstruction)
      • History of enlarged prostate
      • History of atropine allergic reaction
      • Taking Combivent (Ipratropium / Albuterol) with drugs that decrease potassium
      • History of low potassium
      • Taking Combivent (Ipratropium / Albuterol) aerosol inhaler
      • History of soybean allergy
      • History of peanut allergy
      Detailed Combivent (Ipratropium / Albuterol) risks & warnings »
      • Adverse effect of all long-acting beta agonist drugs (LABAs)
      • Lowering dose or stopping Dulera (Mometasone / Formoterol) too quickly, especially after long-term treatment
      • Stress such as trauma, surgery, or infection
      • Long-term inactivity
      • History or family history of osteoporosis (postmenopausal bone loss)
      • Long-term use of drugs that cause bone loss
      • History of heart rhythm problems
      • High blood pressure
      • Heart failure
      • Long-term treatment with Dulera (Mometasone / Formoterol)
      • Not vaccinated against chickenpox or measles
      • Age greater than 65 years
      • Dose of Dulera (Mometasone / Formoterol)
      • Duration of treatment
      • History of high internal eye pressure
      • History of cataracts
      • History of glaucoma
      Detailed Dulera (Mometasone / Formoterol) risks & warnings »
      • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Symbicort (Budesonide / Formoterol), a combination drug.
      • History of chronic obstructive pulmonary disease (COPD)
      • COPD includes chronic bronchitis and emphysema
      • Age greater than 65 years
      • Lowering dose or stopping too quickly especially after long-term treatment
      • Stress such as trauma, surgery or infection
      • Not rinsing mouth after use
      • Higher dose of the corticosteroid medication contained in Symbicort (Budesonide / Formoterol)
      • Adverse effect of long-acting beta agonist drugs (LABAs) found in Symbicort (Budesonide / Formoterol), a combination medication.
      • History of arrhythmia, hypertension or heart failure
      Detailed Symbicort (Budesonide / Formoterol) risks & warnings »
      Coming soon.Coming soon.
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Kidneys and liver
      SpirivaAdvairAtroventCombiventDuleraSymbicortTheophylline
      • The kidney is mainly responsible for removing Spiriva (Tiotropium) from the body so people with kidney disease or reduced function need to be watched closely. Spiriva (Tiotropium) can build up in the body and cause certain side effects. Tell your doctor if you develop dry mouth, blurry vision, confusion, sweating, increased heart rate or constipation. You may need to discuss other medication options to treat your COPD.
      • Adrenal suppression can occur if you lower your dose or stop taking Advair Diskus (Fluticasone / Salmeterol) too quickly which is related to one of the medications in the combination. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your medication need to be done slowly and over time. Talk to your doctor before you decrease or stop Advair Diskus (Fluticasone / Salmeterol).
      No kidneys and liver related info.No kidneys and liver related info.
      • Adrenal suppression can occur if you lower your dose or stop taking Dulera (Mometasone / Formoterol) too quickly. Symptoms include joint or muscle pain, extreme low energy, and depression. Changes in your medication need to be done slowly and over time. Talk to your doctor before you decrease or stop Dulera (Mometasone / Formoterol).
      • Adrenal suppression can occur if you lower your dose or stop taking Symbicort (Budesonide / Formoterol) too quickly which is related to one of the medications in the combination. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your medication need to be done slowly and over time. Talk to your doctor before you decrease or stop Symbicort (Budesonide / Formoterol).
      No kidneys and liver related info.
      Weight
      SpirivaAdvairAtroventCombiventDuleraSymbicortTheophylline
      No weight related info.
      • Steroids can slow height growth in kids.
      No weight related info.No weight related info.No weight related info.
      • Steroids can slow height growth in kids.
      No weight related info.
      Upsides and benefits
      SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
      • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
      • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
      • You only need to take it once a day.
      • 2-in-1 medicine that lowers inflammation and opens airways in your lungs. Medicines are more effective together than alone.
      • Makes lung function significantly better.
      • Lowers the number of flare-ups and rescue inhaler uses in asthma and COPD.
      • You only have to use it twice a day.
      • Both the Diskus and inhaler can be used to treat asthma.
      Coming soon
      • 2-in-1 medicine that opens airways and makes it easier to breathe. Medicines are more effective together than alone.
      • Effectively relieves COPD and asthma symptoms.
      • Respimat formulation has a clear display for dosing, doesn't require shaking, and only needs one inhalation per dose.
      • It's a combination medicine that lowers inflammation and opens airways in your lungs.
      • Significantly improves lung function and lowers the number of flare-ups by 70%. Also reduces rescue inhaler use in asthma.
      • By inhaling this medication, it gets into your lungs quickly and doesn't affect the rest of your body as much, so if should have a lower risk of side effects.
      • Some people who take Dulera (Mometasone / Formoterol) are able to use their fast-acting rescue inhalers less often.
      • 2-in-1 medicine that lowers inflammation and opens airways in your lungs. Medicines are more effective together than alone.
      • Makes lung function significantly better.
      • Lowers the number of flare-ups and rescue inhaler uses in asthma and COPD.
      • In studies, shown to improve asthma symptoms, rescue inhaler use, and lung function on the first day.
      Coming soonComing soon
      Downsides and risks
      SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
      • Won't cure your COPD (but it will relieve your symptoms).
      • You'll need to use this medicine for a long time, and you have to take it every day.
      • Can make symptoms of enlarged prostate or urinary blockage worse.
      • Can worsen a certain type of glaucoma.
      • You might feel dizzy or have blurry vision while taking this medicine.
      • You have to use Advair every day to control your symptoms.
      • You can't lower the dose or stop taking it too suddenly.
      • The HFA inhaler isn't approved to treat COPD.
      • Can make your heart race.
      • Steroids can slow height growth in kids.
      • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
      • There have been some reports of worsening asthma leading to death when taking this medicine.
      Coming soon
      • You have to use Combivent four times a day.
      • Can make your heart race.
      • Can make symptoms of enlarged prostate or urinary blockage worse.
      • Can worsen a certain type of glaucoma.
      • You need to use Dulera (Mometasone / Formoterol) twice a day to control your symptoms.
      • It doesn’t stop a sudden asthma attack. You always need to have a rescue inhaler close by to treat sudden symptoms or breathing problems.
      • Steroids can suppress your immune system, so you can catch bacterial and viral infections easier while on this.
      • You may need to take a different medicine if your asthma doesn’t improve and you need your rescue inhaler more often, or if tests show that your lung function is reduced.
      • You have to use Symbicort twice a day, every day to control your symptoms.
      • You can't lower the dose or stop taking it too suddenly.
      • Lower doses are not as effective for COPD.
      • Can make your heart race.
      • Steroids can slow height growth in kids.
      • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
      • There have been some reports of worsening asthma leading to death when taking this medicine.
      Coming soonComing soon
      Tips from our pharmacists for people taking the medication
      SpirivaAdvairAtroventCombiventDuleraSymbicortTheophyllineTheophylline
      • Don't swallow the capsule. Insert the capsule into an inhaler device only.
      • Use daily to control your COPD.
      • Starts working the first few hours, but it may take longer to feel full effects.
      • Prevents breathing problems, but doesn't stop sudden cough or wheezing once they start.
      • Don't breathe out into the inhaler.
      • You might feel dizzy and notice changes in your vision.
      • Don't use it if you have an allergy to atropine.
      • Contains lactose, so don't use it if you're allergic to milk protein.
      • Lowers inflammation and opens airways to improve breathing.
      • Starts working in about 30 minutes, but it can take 1 to 2 weeks to feel the full effects.
      • Prevents asthma symptoms, but doesn't treat sudden wheezing or asthma attacks once they start.
      • Use inhaler in a level position, and don't breathe out into the device.
      • Rinse your mouth out with water after each use.
      • Shake inhaler for 5 seconds before you use it.
      • Pump the inhaler 4 times before inhaling the first dose, or if it's been more than a month since your last dose.
      • Call 911 or your doctor if it's hard to breathe or you have an asthma attack while on this medication.
      • Diskus contains lactose, so don't use it if you're allergic to milk protein.
      Coming soon
      • Starts working in 15 to 30 minutes, and lasts about 4 to 6 hours.
      • Make sure to read the instructions about how to set up your first dose.
      • Clean the mouthpiece with a damp cloth once a week.
      • The inhaler shows you how much medication you have left so you can plan ahead for refills.
      • Don't take it more often or change your dose without talking to your doctor first.
      • Tell your doctor if the medication stops working or if your symptoms get worse.
      • One type of inhaler contains soya lecithin, so don't use if you have soybean, peanut, or allergies to atropine.
      • Starts working right away, but it can take 1 to 2 weeks to feel the full effects.
      • Inhale two separate puffs in the morning and two separate puffs in the evening. It’s important to read the information that comes with your medicine so you use it the correctly.
      • Clean the mouthpiece with a dry cloth every 7 days and don’t wash it with water.
      • Rinse your mouth out with water after each use to lower your chance of getting a yeast infection (thrush) in the mouth and throat.
      • Lowers inflammation and opens airways to improve breathing.
      • Prevents breathing problems, but doesn't stop sudden cough or wheezing once they start.
      • Starts working in about 30 minutes, but can take 1 to 2 weeks to feel full effects.
      • Use inhaler in a level position, and don't breathe out into the device.
      • Rinse your mouth out with water after each use.
      • Shake inhaler for 5 seconds before you use it.
      • Pump the inhaler 4 times before inhaling the first dose, or if it's been more than a month since your last dose.
      • Call 911 or your doctor if it's hard to breathe, or if you have an asthma attack while taking this medication.
      Coming soonComing soon
      Learn more
      More about SpirivaSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Spiriva (Tiotropium)?
      Worth itNot sureNot worth it
      More about AdvairSide effectsReviews & ratingsFDA package insert
      Have you used Advair Diskus (Fluticasone / Salmeterol)?
      Worth itNot sureNot worth it
      More about AtroventSide effectsReviews & ratingsFDA package insert
      Have you used Atrovent (Ipratropium)?
      Worth itNot sureNot worth it
      More about CombiventSide effectsReviews & ratingsFDA package insert
      Have you used Combivent (Ipratropium / Albuterol)?
      Worth itNot sureNot worth it
      More about DuleraSide effectsReviews & ratingsFDA package insert
      Have you used Dulera (Mometasone / Formoterol)?
      Worth itNot sureNot worth it
      More about SymbicortSide effectsReviews & ratingsFDA package insert
      Have you used Symbicort (Budesonide / Formoterol)?
      Worth itNot sureNot worth it
      More about TheophyllineSide effectsReviews & ratingsFDA package insert
      Have you used Theo-24 (Theophylline)?
      Worth itNot sureNot worth it
      More about TheophyllineSide effectsReviews & ratingsFDA package insert
      Have you used Theo-24 (Theophylline)?
      Worth itNot sureNot worth it