Azulfidine

(Sulfasalazine)

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Reduces inflammation.

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Our bottom line

Azulfidine (Sulfasalazine) is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis.

Quick facts about Sulfasalazine
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sulfasalazine)
Prices and discounts
Lowest price for 120 500mg tablets
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$15.66

Upsides

  • Can slow down the progression of your rheumatoid arthritis.
  • Helps control your stomach problems if you're taking it for ulcerative colitis.

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Downsides

  • Requires constant lab monitoring, at least every other week when you first start using it.
  • Not a good option if you have kidney or liver disease.
  • If you're allergic to sulfa drugs or aspirin, you can't take Azulfidine (Sulfasalazine).
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.

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Get our free fact sheet

What to expect from Sulfasalazine, on one page

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Prices and discounts
Lowest price for 120 500mg tablets
Determining your location...
$15.66
How it works

Azulfidine (Sulfasalazine) is an anti-inflammatory drug that reduces inflammation and pain.

Quick facts about Sulfasalazine
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sulfasalazine)

Dosage forms

  • Pill
  • Extended release
Tried Sulfasalazine? Write a review!

What to expect when you take Azulfidine (Sulfasalazine) for Ulcerative colitis

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Side effect rates for Azulfidine (Sulfasalazine)

  • Nausea
  • Stomach problems
  • Rash
  • Headache
  • Stomach pain
  • Vomiting
  • Fever
  • Dizziness

Risks and Warnings for Azulfidine (Sulfasalazine)

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  • You'll need to get complete blood counts done before starting Azulfidine (Sulfasalazine), and every other week during the first three months of treatment. Since kidney damage can occur, you'll also need a urinalysis and an assessment of your kidney function periodically during treatment. If you notice a sore throat, fever, pale or yellow skin, these may be caused by a serious blood problem or liver damage. Let your doctor know if you have any of these symptoms.

Common concerns from people taking Azulfidine (Sulfasalazine)

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Interactions
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
Food
  • Swallow Azulfidine (Sulfasalazine) tablets whole, and take after a meal with a full glass of water. It's important to drink at least 6 glasses of water every day while using Azulfidine (Sulfasalazine).
Kidneys and liver
  • Not a good option if you have kidney or liver disease.