Prescription onlyLower-cost generic availableClass: Neuro/psych

Symbyax

(olanzapine / fluoxetine)

Prescription onlyLower-cost generic availableClass: Neuro/psych
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Treats depression and bipolar disorder.

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Our bottom line

Symbyax (olanzapine / fluoxetine) is recommended for people who have bipolar disorder with depression, but you're likely to have issues with weight gain and blood sugar.

Prices and discounts
Lowest price for 30 6mg/25mg capsules
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$116.63

Upsides

  • The combination of medicines in Symbyax (olanzapine / fluoxetine) is recommended for people age 10 and older who have bipolar disorder with depression, since it stops people from having manic episodes.
  • Symbyax (olanzapine / fluoxetine) can help people with depression who haven’t had enough improvement with other medications.
  • Symbyax (olanzapine / fluoxetine) reduces the number of pills you have to take per day.
  • Available in generic form, so it can be less costly.
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Downsides

  • Symbyax (olanzapine / fluoxetine) is available only in certain fixed strengths, so it can be hard to customize dosing.
  • It may take 4 to 6 weeks to experience the full benefits of the medication.
  • Your doctor might have to change the dose of Symbyax (olanzapine / fluoxetine) several times before he/she finds a dose that works best for you.
  • Stopping Symbyax (olanzapine / fluoxetine) suddenly can make your depression or bipolar disorder worse.
Prices and discounts
Lowest price for 30 6mg/25mg capsules
Determining your location...
$116.63
How it works

Symbyax (olanzapine / fluoxetine) contains 2 medicines: fluoxetine and olanzapine. It raises chemicals in your brain that regulate your mood.

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Dosage forms
  • Pill

What to expect when you take Symbyax (olanzapine / fluoxetine) for Bipolar disorder or depression

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Side effect rates for Symbyax (olanzapine / fluoxetine)

Risks and Warnings for Symbyax (olanzapine / fluoxetine)

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    • Higher risk if:
    • People age 24 and younger

    Taking Symbyax (olanzapine / fluoxetine) can make you more likely to harm yourself or commit suicide, especially if you are age 24 and younger, and during the first few weeks of taking it. Symbyax (olanzapine / fluoxetine) isn’t approved for children under age 10. If your mood darkens and you want to hurt yourself or other people, call the doctor right away.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Symbyax (olanzapine / fluoxetine)

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Weight
  • Symbyax (olanzapine / fluoxetine) can cause higher weight, blood sugar, cholesterol, and triglycerides (fat), especially in children ages 10 to 17. If you or your child has diabetes, high blood pressure, or heart disease, your doctor might change your medicines and do regular blood tests. Eat healthy and exercise regularly. If you experience excessive thirst, hunger, urination, or weakness, check your blood sugar right away. Report any changes you notice to your doctor.