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Lowers thyroid hormones.

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Prescription onlyLower-cost generic available

Our bottom line

Tapazole (Methimazole) is an effective medicine to lower thyroid levels, but it requires frequent blood tests and monitoring for serious side effects.


  • For certain conditions, Tapazole (Methimazole) is an effective anti-thyroid alternative to surgery or radioactive iodine.
  • Tapazole (Methimazole) is preferred for children since other antithyroid medicines can cause serious liver damage.
  • For pregnant women, Tapazole (Methimazole) is preferred during the second and third trimesters.


  • You may need frequent dose adjustments when you first start taking Tapazole (Methimazole) or if your health changes.
  • Periodic blood tests are needed to make sure you're getting the right dose and to watch for side effects.
  • Tapazole (Methimazole) can cause birth defects. It is not recommended during the first trimester of pregnancy.
  • Because [name-common] can affect the liver, it isn't recommended for people who have liver problems.

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What to expect when you take Tapazole (Methimazole)

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Tips from our pharmacists
  • Tapazole (Methimazole) is typically taken 3 times a day. Once you're on the right dose, you may be able to take it once a day.
  • It may take 6 to 12 weeks before seeing an improvement of symptoms.
  • Tapazole (Methimazole) may make you bleed more easily. Use a soft toothbrush and an electric razor.
  • Tapazole (Methimazole) may lower your immune system. Try to avoid people who have an infection. Talk to your doctor if you suddenly get a fever.
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Side effects for Tapazole (Methimazole)

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These are side effects of Tapazole (Methimazole) reported to the FDA by people taking it, and by doctors and pharmacists.

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Risks and Warnings for Tapazole (Methimazole)

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    • Higher risk if:
    • Taking other blood-thinning drugs

    Tapazole (Methimazole) can increase the risk of bleeding or bruising if you're also taking aspirin, NSAIDs (like ibuprofen), warfarin, or other anticoagulants. Tell your doctor about any bruising that doesn't improve, black stools, pink or red urine, or unusual bleeding (for example, from the nose or gums).

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Tapazole (Methimazole)

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The FDA category for this medication is D. It is advised that you: Weigh risks vs. benefits