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Lowers thyroid hormones.

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Tapazole (Methimazole) is an effective medicine to lower thyroid levels, but it requires frequent blood tests and monitoring for serious side effects.

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  • For certain conditions, Tapazole (Methimazole) is an effective anti-thyroid alternative to surgery or radioactive iodine.
  • Tapazole (Methimazole) is preferred for children since other antithyroid medicines can cause serious liver damage.
  • For pregnant women, Tapazole (Methimazole) is preferred during the second and third trimesters.


  • You may need frequent dose adjustments when you first start taking Tapazole (Methimazole) or if your health changes.
  • Periodic blood tests are needed to make sure you're getting the right dose and to watch for side effects.
  • Tapazole (Methimazole) can cause birth defects. It is not recommended during the first trimester of pregnancy.
  • Because [name-common] can affect the liver, it isn't recommended for people who have liver problems.
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Side effect rates for Tapazole (Methimazole)

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These are side effects of Tapazole (Methimazole) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Tapazole (Methimazole)

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    • Higher risk if:
    • Taking other blood-thinning drugs

    Tapazole (Methimazole) can increase the risk of bleeding or bruising if you're also taking aspirin, NSAIDs (like ibuprofen), warfarin, or other anticoagulants. Tell your doctor about any bruising that doesn't improve, black stools, pink or red urine, or unusual bleeding (for example, from the nose or gums).

Common concerns from people taking Tapazole (Methimazole)

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Kidneys and liver
  • Because [name-common] can affect the liver, it isn't recommended for people who have liver problems.