Prescription onlyLower-cost generic availableClass: Cardiovascular

Tenex Alternatives

(guanfacine)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Tenex (guanfacine) to alternatives

These medications are comparable to Tenex (guanfacine) or used for similar purposes.

Tenex
(guanfacine)

Kapvay
(clonidine)

Treats ADHD and lowers blood pressure. Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.Treats attention deficit hyperactivity disorder. Kapvay (clonidine) is one of the few medicines for ADHD that isn't a stimulant and not addictive, but it can lower your blood pressure.
Reviews & ratings
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Have you used Tenex (guanfacine)?
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Have you used Kapvay (clonidine)?
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Side effects
TenexKapvay
  • Dry Mouth 1%
  • Dizziness 2%
  • Any side effect 3%
  • Asthenia 2%
  • Somnolence 13%
  • Impotence 3%
  • Constipation 5%
More Tenex side effects »
  • Sleepiness 34%
  • Headache 4%
  • Fatigue 15%
  • Upper abdominal pain 3%
  • Irritability 5%
  • Dizziness 2%
  • Insomnia 4%
  • Emotional disorder 3%
  • Nightmare 4%
  • Nausea 1%
More Kapvay side effects »
How it works
TenexKapvay
Tenex (Guanfacine) is a centrally-acting alpha agonist medication. It lowers blood pressure by slowing down the heart rate and relaxing the blood vessels. It's not clear how Tenex (Guanfacine) works in ADHD, but it's used when stimulants haven't worked or can't be used in people.Kapvay (clonidine) is an alpha-2 agonist. It's not entirely clear how it works for ADHD, but it lowers the activity of certain stress hormones in the brain.
Type of medication
TenexKapvay
Prescription onlyPrescription only
Available as
TenexKapvay
  • Pill
  • Extended release
  • Extended release
Used for
TenexKapvay
Risk factors for serious side effects
TenexKapvay
  • Taking other medications that cause sedation or sleepiness
  • Stopping Tenex (Guanfacine) suddenly to treat high blood pressure
Detailed Tenex (guanfacine) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Stopping Kapvay (clonidine) suddenly
Detailed Kapvay (clonidine) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Alcohol
TenexKapvay
  • Limit the amount of alcohol you drink while taking this.
No alcohol related info.
Sleep
TenexKapvay
  • People report having sleepiness or sedation while on Tenex (Guanfacine). You're at higher risk for this if you're taking other medications that have similar effects. Don't drive or do anything that requires concentration until you know how Tenex (Guanfacine) affects you.
  • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
  • People who take Kapvay (clonidine) can feel very sleepy during the day. It can be worse if you're taking other medicines that also make you sleepy, like pain medicines, or medicines for anxiety. Be very careful driving or doing anything that requires your full concentration until you know how your body reacts to it.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
Upsides and benefits
TenexKapvay
  • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
  • It's not a "controlled medication".
  • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
  • Available as a generic medication, so it should be more affordable than other options.
  • Can be used alone or together with a stimulant-type medicine to treat ADHD.
  • Also treats blood pressure and some nervous system and psychiatric conditions.
  • Kapvay (clonidine) is available in generic.
Downsides and risks
TenexKapvay
  • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
  • Not a preferred drug to control blood pressure.
  • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
  • Kapvay (clonidine) is not a first choice medicine to treat ADHD.
  • Kapvay (clonidine) can make you feel very dizzy or cause low blood pressure.
  • Stopping Kapvay (clonidine) suddenly can cause your blood pressure to jump and your heart to beat very fast.
  • It can take up to two weeks of taking Kapvay (clonidine) to notice any changes in behavior.
  • Kapvay (clonidine) has to be swallowed whole, which can be hard for some children to do.
Tips from our pharmacists for people taking the medication
TenexKapvay
  • Don't stop taking Tenex (Guanfacine) without talking to your doctor first.
  • Limit the amount of alcohol you drink while taking this.
  • Drink plenty of liquids and don't get overheated while taking Tenex (Guanfacine).
  • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
  • Can take up to 2 weeks for the maximum effect.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • You might have to take Kapvay (clonidine) for at least two weeks before you notice any changes.
  • Don't stop taking this medicine suddenly without talking to your doctor.
  • Swallow Kapvay (clonidine) whole. Don't chew, cut or crush the pill.
  • If you forget your daily dose of Kapvay (clonidine), skip it for that day. Don't double up the next day.
Learn more
More about TenexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tenex (guanfacine)?
Worth itNot sureNot worth it
More about KapvaySide effectsReviews & ratingsFDA package insert
Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it