Prescription onlyLower-cost generic availableClass: Cardiovascular

TenexAlternatives

(guanfacine)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Tenex (guanfacine) to alternatives

These medications are comparable to Tenex (guanfacine) or used for similar purposes.

Tenex
(guanfacine)

Kapvay
(clonidine)

Treats ADHD and lowers blood pressure. Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.
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Reviews & ratings
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Have you used Tenex (guanfacine)?
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Side effects
TenexKapvay
  • Dry mouth 1%
  • Dizziness 2%
  • Any side effect 3%
  • Muscle weakness 2%
  • Drowsiness 13%
  • Impotence 3%
  • Constipation 5%
More Tenex side effects »
  • Drowsiness 34%
  • Headache 4%
  • Fatigue 15%
  • Upper abdominal pain 3%
  • Irritability 5%
  • Any side effect 6%
  • Dizziness 2%
  • Sleep difficulty 4%
  • Nausea 1%
  • Emotional disorder 3%
More Kapvay side effects »
How it works
TenexKapvay
Tenex (Guanfacine) is a centrally-acting alpha agonist medication. It lowers blood pressure by slowing down the heart rate and relaxing the blood vessels. It's not clear how Tenex (Guanfacine) works in ADHD, but it's used when stimulants haven't worked or can't be used in people.Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.
Type of medication
TenexKapvay
Prescription only
Prescription only
Available as
TenexKapvay
  • Pill
  • Extended release
  • Extended release
Used for
TenexKapvay
Risk factors for serious side effects
TenexKapvay
  • Taking other medications that cause sedation or sleepiness
  • Stopping Tenex (Guanfacine) suddenly to treat high blood pressure
Detailed Tenex (guanfacine) risks & warnings »
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
    Detailed Kapvay (clonidine) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    TenexKapvay
    • Limit the amount of alcohol you drink while taking this.
    No alcohol related info.
    Sleep
    TenexKapvay
    • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
    • People report having sleepiness or sedation while on Tenex (Guanfacine). You're at higher risk for this if you're taking other medications that have similar effects. Don't drive or do anything that requires concentration until you know how Tenex (Guanfacine) affects you.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    Upsides and benefits
    TenexKapvay
    • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
    • It's not a "controlled medication".
    • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
    • Available as a generic medication, so it should be more affordable than other options.
    • Can be used alone or together with a stimulant-type medicine to treat ADHD.
    • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
    • Also treats blood pressure and some nervous system and psychiatric conditions.
    Downsides and risks
    TenexKapvay
    • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
    • Not a preferred drug to control blood pressure.
    • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
    • Can lower blood pressure.
    • The pill form can make some people sleepy, dizzy, and have dry mouth.
    • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    Tips from our pharmacists for people taking the medication
    TenexKapvay
    • Don't stop taking Tenex (Guanfacine) without talking to your doctor first.
    • Limit the amount of alcohol you drink while taking this.
    • Drink plenty of liquids and don't get overheated while taking Tenex (Guanfacine).
    • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
    • Can take up to 2 weeks for the maximum effect.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    • For ADHD: Might take up to 2 weeks to see effects.
    • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • If side effects don't go away, talk to your doctor about alternatives.
    • Don't stop taking this medicine suddenly.
    Learn more
    More about TenexSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tenex (guanfacine)?
    Worth itNot sureNot worth it
    More about KapvaySide effectsReviews & ratingsFDA package insert
    Have you used Kapvay (clonidine)?
    Worth itNot sureNot worth it