Prescription onlyLower-cost generic available

Toprol Xl Alternatives

(Metoprolol Succinate)

  • Pill
  • Extended release
Back to: Full Site Navigation

Compare Toprol Xl (Metoprolol Succinate) to alternatives

These medications are comparable to Toprol Xl (Metoprolol Succinate) or used for similar purposes.

Toprol Xl
(Metoprolol Succinate)

Cozaar
(Losartan)

Lopressor
(Metoprolol Tartrate)

Coreg
(Carvedilol)

Norvasc
(Amlodipine)

Bystolic
(Nebivolol)

Microzide
(Hydrochlorothiazide )

Inderal
(Propranolol)

Tenormin
(Atenolol)

Zestril
(Lisinopril)

Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Bystolic (Nebivolol) is a good blood pressure-lowering medicine for people with heart conditions, and has fewer side effects than other beta blockers, but it's expensive. You can't miss doses.Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.Lowers blood pressure and controls heart rate. Tenormin (Atenolol) is good for controlling chest pain and treating heart failure and heart attack with fewer side effects than other beta blockers. You have to take it on an empty stomach, and you can't miss doses.Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.220858895705521Toprol XL
Reviews for Toprol Xl (Metoprolol Succinate)
60%
of people say Toprol Xl (Metoprolol Succinate) is worth it
55%
say it works well
13%
say it's a big hassle
Reviews for Cozaar (Losartan)
57%
3% vs. Toprol Xl (Metoprolol Succinate)
47%
8% vs. Toprol Xl (Metoprolol Succinate)
16%
3% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Lopressor (Metoprolol Tartrate)
61%
+1% vs. Toprol Xl (Metoprolol Succinate)
46%
9% vs. Toprol Xl (Metoprolol Succinate)
15%
2% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Coreg (Carvedilol)
54%
6% vs. Toprol Xl (Metoprolol Succinate)
46%
9% vs. Toprol Xl (Metoprolol Succinate)
18%
5% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Norvasc (Amlodipine)
59%
1% vs. Toprol Xl (Metoprolol Succinate)
50%
5% vs. Toprol Xl (Metoprolol Succinate)
14%
1% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Bystolic (Nebivolol)
51%
9% vs. Toprol Xl (Metoprolol Succinate)
46%
9% vs. Toprol Xl (Metoprolol Succinate)
18%
5% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
13% vs. Toprol Xl (Metoprolol Succinate)
31%
24% vs. Toprol Xl (Metoprolol Succinate)
15%
2% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Inderal (Propranolol)
62%
+2% vs. Toprol Xl (Metoprolol Succinate)
58%
+3% vs. Toprol Xl (Metoprolol Succinate)
17%
4% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Tenormin (Atenolol)
57%
3% vs. Toprol Xl (Metoprolol Succinate)
48%
7% vs. Toprol Xl (Metoprolol Succinate)
16%
3% vs. Toprol Xl (Metoprolol Succinate)
Reviews for Zestril (Lisinopril)
61%
+1% vs. Toprol Xl (Metoprolol Succinate)
51%
4% vs. Toprol Xl (Metoprolol Succinate)
13%
Same vs. Toprol Xl (Metoprolol Succinate)
Side effects
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Low blood sugar 4%
  • Low blood pressure 4%
  • Muscle weakness/fatiguea/fatigue 4%
  • Hyperkalemia 4%
  • Chest pain 4%
  • Low red blood cells 3%
  • Muscular weakness 3%
  • Orthostatic hypotension 3%
More Losartan side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • First-degree heart block 3%
More Lopressor side effects »
  • Dizziness 13%
  • Abnormally slow heartbeat 7%
  • Low blood pressure 6%
  • Diarrhea 6%
  • High blood sugar 4%
  • Nausea 4%
  • Vision abnormal 3%
  • Fainting 3%
  • Muscle weakness 2%
  • Edema dependent 2%
More Coreg side effects »
  • Swelling due to excess fluid 10%
  • Fatigue 2%
  • Nausea 1%
  • Dizziness 1%
More Norvasc side effects »
  • Fatigue 4%
  • Headache 3%
  • Dizziness 2%
  • Diarrhea 1%
More Bystolic side effects »

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »
  • Dizziness 5%
  • Fatigue 4%
More Propranolol side effects »
  • Tiredness 13%
  • Dizziness 7%
  • Cold extremities 7%
  • Low mood disorder 3%
  • Vivid dreams 2%
  • Shortness of breath 2%
  • Leg pain 2%
  • Nausea 2%
  • Diarrhea 1%
  • Fatigue 1%
More Atenolol side effects »
  • Dizziness 7%
  • Headache 4%
  • Cough 3%
  • Diarrhea 2%
  • Chest pain 2%
  • Fatigue 2%
  • Upper respiratory infection 1%
More Lisinopril side effects »
How it works
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Bystolic (Nebivolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Inderal (Propranolol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Tenormin (Atenolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it less work to pump.Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Calcium channel blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Diuretic
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Available as
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Pill
Used for (click to learn more)
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
Risk factors for serious side effects
Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Toprol Xl (Metoprolol Succinate) risks & warnings »
    Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
    Pregnancy category
    Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Take it with food.
    • You have to take Carvedilol with food.
    • Take it with food.
    No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    Sex
    No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
    • Toprol XL is the extended release version of Lopressor.
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
    • A first-choice treatment to prevent chest pain (angina).
    • A first-choice treatment for heart failure and heart attack.
    • Calcium channel blockers work especially well for African Americans to lower blood pressure.
    • Prevents heart-related chest pain (angina) if you take it regularly.
    • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
    • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Controls your heart rate to reduce work for your heart.
    • A first-line treatment for heart failure and heart attack.
    • Helps to lower blood pressure if you can't use first-choice treatments or need additional blood pressure control.
    • Many beta blockers can worsen asthma or cause headaches, but Bystolic usually doesn't because it targets the heart more specifically and causes fewer side effects.
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    • Lowers the risk of heart attack and stroke.
    • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
    • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
    • A first-choice treatment to prevent chest pain (angina).
    • At lower doses, Atenolol has fewer side effects than most beta blockers because it targets the heart and doesn't cross into the brain and central nervous system.
    • A first-choice treatment to prevent chest pain (angina).
    • A first-choice treatment for heart failure and heart attack.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    Downsides and risks
    Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
    • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • You have to take Carvedilol with food.
    • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
    • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
    • Some people might experience flushing with this medication.
    • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
    • Might not be a good choice if you have liver disease.
    • Not available in less expensive generic form.
    • You can't miss doses. Stopping Bystolic suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
    • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • You have to take Atenolol on an empty stomach.
    • You can't miss doses. Stopping Atenolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    Tips from our pharmacists for people taking the medication
    Toprol XLLosartanLopressorCoregNorvascBystolicHydrochlorothiazidePropranololAtenololLisinopril
    • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
    • Take it with food.
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Can cause fatigue and erectile dysfunction.
    • Take it with food.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Interacts with the cholesterol medicine Simvastatin.
    • Can cause ankle or foot swelling.
    • Can cause gum overgrowth. Ask your dentist to check for this side effect.
    • Can cause headache, dizziness, or feeling short of breath in the first few days.
    • If side effects don't go away, talk to your doctor about alternatives.
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Can cause insomnia and fatigue.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Take it on an empty stomach.
    • Can cause fatigue and insomnia.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    Learn more
    More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert
    More about LosartanSide effectsReviews & ratingsFDA package insert
    More about LopressorSide effectsReviews & ratingsFDA package insert
    More about CoregSide effectsReviews & ratingsFDA package insert
    More about NorvascSide effectsReviews & ratingsFDA package insert
    More about BystolicSide effectsReviews & ratingsFDA package insert
    More about HydrochlorothiazideSide effectsReviews & ratingsFDA package insert
    More about PropranololSide effectsReviews & ratingsFDA package insert
    More about AtenololSide effectsReviews & ratingsFDA package insert
    More about LisinoprilSide effectsReviews & ratingsFDA package insert