Prescription onlyLower-cost generic availableClass: Pain

Ultram

(tramadol)

Prescription onlyLower-cost generic availableClass: Pain
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Treats moderate to severe pain.

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Prescription opioids are used to treat several kinds of pain - but they carry significant risks, including addiction. Learn more about these drugs and be sure to discuss the risks with your doctor.

Our bottom line

Ultram (tramadol) works well for pain. Although it's a little weaker than other opioids, it can still be addictive.

Price and discounts
Prices and coupon for 120 (50mg) tablets of tramadol

Upsides

  • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
  • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
  • Has a lower chance of causing breathing problems compared to other typical opioids.
  • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
People say this drug is:
642 reviews

Downsides

  • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
  • Like other opioid pain relievers, Ultram (tramadol) has a high risk of addiction, abuse, misuse, overdose, and death.
  • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
  • It's a controlled substance regulated by the federal government. This means that your use of Ultram (tramadol) will be tracked to prevent potential prescription abuse.
  • Like all opioids, don't use when pregnant, since the baby can become dependent on it and have withdrawal symptoms after birth.
How it works

Ultram (tramadol) is an opioid pain reliever. Researchers don't know exactly how it works, but it alters certain brain chemicals to lower pain perception and improve mood.

What to expect when you take Ultram (tramadol) for Pain

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Side effect rates for Ultram (tramadol)

427 From clinical trials of Tramadol / Pain
  • Dizziness
  • Constipation
  • Nausea
  • Headache
  • Sleepiness
  • Vomiting
  • Itching
  • Cns stimulation
  • Muscle weakness
  • Sweating

Risks and Warnings for Ultram (tramadol)

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  • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Ultram (tramadol)

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Pregnancy
Interactions
  • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
Food
  • Take Ultram (tramadol) with food to avoid an upset stomach.
  • Take it as prescribed with food.
  • Take with food as it may cause nausea on an empty stomach. Lower doses seem to act as a "pick-me-up", while higher doses cause drowsiness. Split your daily dose accordingly. ABSOLUTELY causes physical dependency after regular, long-term use. The withdraw is more mild than other opioids though, more uncomfortable than anything. Recommend stepping down over a period of weeks rather than stopping the medication altogether.
  • I took tramadol for years as a breakthrough medication for chronic pain. I suffer from lemierres syndrome and as a result ALL muscle had to be removed from my pelvis. I was given nucynta as an alternative (it's basically tramadol on steroids and still an opoid NOT and opiate) and it was much better. Unfortunately, nucynta does not have a generic version so my new insurance doesn't cover it. i was put back on tramadol and it does NOTHING to help.
Kidneys and liver
  • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
Pain
  • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
  • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
  • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
  • worked great for nerve damage pain but side effects made you almost completely unable to feel emotions, you are a robot, use it only if you NEED it badly
  • A godsend for my chronic nerve pain; doesn't have the sheer pain relief power of stronger opioids, but it does diminish the perception of pain enough for me to work and have a life. Equally important, it takes the edge of my chronic anxiety so I can keep that under control as well. I take (4) 50-mg tablets daily along with ibuprofen and a muscle relaxant.
  • I wouldn't be able to function well without it due to pain. Thanks to it, I am so far avoiding extensive neck surgery, It also helps by serving as a mild antidepressant. If it effects you sexually, ask your doctor to add the antidepressant
Sleep
  • Causes drowsiness -- take caution
  • makes me extremely drowsy and foggy after I wake up when taking it.
  • Take with food as it may cause nausea on an empty stomach. Lower doses seem to act as a "pick-me-up", while higher doses cause drowsiness. Split your daily dose accordingly. ABSOLUTELY causes physical dependency after regular, long-term use. The withdraw is more mild than other opioids though, more uncomfortable than anything. Recommend stepping down over a period of weeks rather than stopping the medication altogether.
Weight
  • Slows down my digestion enough that I have bloating when I eat sugar or dairy, in addition to opioid induced constipation
  • Didn't seem to get any relief or uphoria. Took it for years & had weight gain during this time. If it helped my mood I didn't notice.