Prescription onlyLower-cost generic available



Prescription onlyLower-cost generic available
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
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Treats moderate to severe pain.

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Prescription opioids are used to treat several kinds of pain - but they carry significant risks, including addiction. Learn more about these drugs and be sure to discuss the risks with your doctor.

Our bottom line

Ultram (Tramadol) works well to treat severe pain and mood changes. Although it's a little weaker than other opioids, it can still be addictive.

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  • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
  • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
  • Has a lower chance of causing breathing problems compared to other typical opioids.
  • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
People say this drug is:
598 reviews


  • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
  • Like other opioid pain relievers, Tramadol has a high risk of addiction, abuse, misuse, overdose, and death. It should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
  • It isn't used for short-term, as-needed pain relief.
  • It's a controlled substance regulated by the federal government. This means that your use of Ultram (Tramadol) will be tracked to prevent potential prescription abuse.
  • To get Ultram (Tramadol) in the pharmacy, you'll need to bring in a paper prescription directly from your doctor.

What to expect when you take Ultram (Tramadol) for Pain

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Side effect rates for Ultram (Tramadol)

From clinical trials of Tramadol / Any condition
  • Widening of blood vessels
  • Abdominal pain
  • Anxiety
  • Confusion
  • Coordination disturbance
  • Euphoria
  • Constricted pupil
  • Nervousness
  • Sleep disorder
  • Feeling unwell

Risks and Warnings for Ultram (Tramadol)

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    • Higher risk if:
    • Higher dose
    • Using other medicines that can cause seizures
    • History of seizures
    • Alcoholism
    • Eating disorders
    • Brain infections

    Ultram (Tramadol) can lower the brain's threshold for seizures in people with certain risk factors. Use with caution.

Common concerns from people taking Ultram (Tramadol)

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  • Take Ultram (Tramadol) with food to avoid an upset stomach.
  • Take it as prescribed with food.
Kidneys and liver
  • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
  • It works better than neurotin. Since I have liver issues its the only thing drs will prescribe even though it does very little. I laugh when it states for moderate to severe pain. Maybe for a splinter or toe jam.
  • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
  • It isn't used for short-term, as-needed pain relief.
  • worked great for nerve damage pain but side effects made you almost completely unable to feel emotions, you are a robot, use it only if you NEED it badly
  • From dental to backaches this is for average pain. The benefit is it improves/elevates moods, almost like a depression drug. It is vitalto take on time and not to sudden stop or skip cause can cause mood swings, makes ur body hot & sweats.
  • Not effective for chronic pain.
  • Causes drowsiness -- take caution
  • makes me extremely drowsy and foggy after I wake up when taking it.
  • Slows down my digestion enough that I have bloating when I eat sugar or dairy, in addition to opioid induced constipation