Class: Mental health



Class: Mental health
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Improves mood

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Trintellix (Vortioxetine) is a new type of serotonin modulating antidepressant that can be tried when the other antidepressants don't work, but some people may find the side effects intolerable and the cost expensive.

Price and discounts
Best available price for 30 (10mg) tablets of vortioxetine


  • Relieves depression symptoms.
  • May improve memory.
  • Possibly less side effect on sex drive/enjoyment compared to other antidepressants.
  • Works differently than other serotonine modifying antidepressants.
People say this drug is:
19 reviews


  • Likely expensive since insurance may not cover it.
  • Stomach issues, particularly nausea, can be persistant for some people.
  • Higher likelihood of interaction with other medications.
How it works

Trintellix (Vortioxetine) is a selective serotonin reuptake inhibitor (SSRI) that also directly effects the serotonine recpetors. It increases amount and effect of serotonine in the brain, which regulates mood.

What to expect when you take Trintellix (vortioxetine) for Depression

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Trintellix (vortioxetine)

0 reports
These are side effects of Trintellix (vortioxetine) reported to the FDA by people taking it, and by doctors and pharmacists.
Filter group. All currently selected
Filter group. All currently selected

Common concerns from people taking Trintellix (vortioxetine)

Final section. Do you want to return to drug navigation?
  • Higher likelihood of interaction with other medications.
  • Make sure it doesn't interact with your other medications.
  • Take with food and/or at night to lessen stomach issues, such as nausea, diarrhea, gas.
  • Couldn't sleep with it