Trintellix Alternatives

(Vortioxetine)

Alternatives

Compare Trintellix (Vortioxetine) to alternatives

These medications are comparable to Trintellix (Vortioxetine) or used for similar purposes.

Trintellix
(Vortioxetine)

Cymbalta
(Duloxetine)

Wellbutrin
(Bupropion)

Celexa
(Citalopram)

Zoloft
(Sertraline)

Remeron
(mirtazapine)

Paxil
(Paroxetine)

Lexapro
(escitalopram)

Prozac
(Fluoxetine)

Effexor
(Venlafaxine)

Improves mood Trintellix (Vortioxetine) is a new type of serotonin modulating antidepressant that can be tried when the other antidepressants don't work, but some people may find the side effects intolerable and the cost expensive.Improves mood and relieves certain kinds of pain. Cymbalta (Duloxetine) is good for treating depression and anxiety, and may help with chronic pain. More likely than other antidepressants to cause problems if you drink or have high blood pressure.Improves mood. Wellbutrin (Bupropion) is good for treating depression and has fewer sexual side effects than other antidepressants, but you need to be okay with avoiding alcohol.Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Improves mood and helps you relax. Zoloft (Sertraline) is good for treating depression and anxiety. It's more likely to cause insomnia and diarrhea than other antidepressants.Improves mood. Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.Improves mood and helps you relax. Paxil (Paroxetine) is good for treating depression and anxiety but it causes more weight gain, sleepiness, and withdrawal symptoms than other antidepressants.Improves mood and helps you relax. Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.Improves mood and helps you relax. Prozac (Fluoxetine) is good for treating depression and anxiety. It's more energizing than other antidepressants, but may not be the best choice for people who have trouble sleeping.Improves mood and helps you relax. Effexor (Venlafaxine) is good for treating depression and anxiety. It may work when other antidepressants haven't, but it's more likely to cause side effects and withdrawal symptoms than other antidepressants.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.11Trintellix
Reviews for Trintellix
53%
of people (All ages) say Trintellix is worth it
53%
say it works well
37%
say it's a big hassle
Have you used Trintellix (Vortioxetine)?
Worth itNot sureNot worth it
Reviews for Cymbalta
58%
-5% worse vs. Trintellix
49%
+4% better vs. Trintellix
24%
-13% worse vs. Trintellix
496 reviews
Have you used Cymbalta (Duloxetine)?
Worth itNot sureNot worth it
Reviews for Wellbutrin
60%
-7% worse vs. Trintellix
40%
+13% better vs. Trintellix
13%
-24% worse vs. Trintellix
1164 reviews
Have you used Wellbutrin (Bupropion)?
Worth itNot sureNot worth it
Reviews for Celexa
61%
-8% worse vs. Trintellix
51%
+2% better vs. Trintellix
16%
-21% worse vs. Trintellix
520 reviews
Have you used Celexa (Citalopram)?
Worth itNot sureNot worth it
Reviews for Zoloft
59%
-6% worse vs. Trintellix
41%
+12% better vs. Trintellix
15%
-22% worse vs. Trintellix
1472 reviews
Have you used Zoloft (Sertraline)?
Worth itNot sureNot worth it
Reviews for Remeron
45%
+8% better vs. Trintellix
39%
+14% better vs. Trintellix
26%
-11% worse vs. Trintellix
152 reviews
Have you used Remeron (mirtazapine)?
Worth itNot sureNot worth it
Reviews for Paxil
52%
+1% better vs. Trintellix
39%
+14% better vs. Trintellix
24%
-13% worse vs. Trintellix
694 reviews
Have you used Paxil (Paroxetine)?
Worth itNot sureNot worth it
Reviews for Lexapro
61%
-8% worse vs. Trintellix
48%
+5% better vs. Trintellix
15%
-22% worse vs. Trintellix
1063 reviews
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
Reviews for Prozac
62%
-9% worse vs. Trintellix
40%
+13% better vs. Trintellix
16%
-21% worse vs. Trintellix
1319 reviews
Have you used Prozac (Fluoxetine)?
Worth itNot sureNot worth it
Reviews for Effexor
62%
-9% worse vs. Trintellix
51%
+2% better vs. Trintellix
23%
-14% worse vs. Trintellix
577 reviews
Have you used Effexor (Venlafaxine)?
Worth itNot sureNot worth it
Side effects
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor

We haven’t found good data for Trintellix side effects.

FDA side effect reports for Trintellix »
  • Abdominal pain 1%
  • Hyperhidrosis 5%
  • Decreased appetite 5%
  • Fatigue 4%
  • Insomnia 4%
  • Constipation 5%
  • Dizziness 4%
  • Diarrhea 3%
  • Somnolencee 7%
  • Dry mouth 8%
More Cymbalta side effects »
  • Anxiety 2%
  • Decreased libido 1%
  • Gustatory disturbance 2%
  • Dyspepsia 1%
  • Hypotension 1%
  • Impaired sleep quality 2%
  • Sensory disturbance 1%
  • Appetite increase 2%
  • Palpitations 2%
More Wellbutrin side effects »
  • Fever 2%
  • Arthralgia 1%
  • Myalgia 1%
  • Yawning 2%
  • Upper Respiratory Tract Infection 2%
  • Abdominal Pain 1%
  • Agitation 2%
  • Dysmenorrhea 1%
  • Impotence 3%
More Celexa side effects »
  • Anorexia 1%
  • Dyspepsia 3%
  • Agitation 2%
  • Ejaculation Failure 7%
  • Sweating Increased 5%
  • Constipation 2%
  • Tremor 8%
  • Fatigue 3%
  • Dizziness 5%
More Zoloft side effects »
  • Back pain 1%
  • Swelling in limbs 1%
  • Muscle pain 1%
  • Tremor 1%
  • Confusion 2%
  • Urinary frequency 1%
  • Abnormal thinking 2%
  • Abnormal dreams 3%
  • Flu syndrome 2%
  • Dizziness 4%
More Remeron side effects »
  • Rash 1%
  • Oropharynx Disorder† 2%
  • Dyspepsia 1%
  • Myopathy 1%
  • Myalgia 1%
  • Drugged Feeling 1%
  • Taste Perversion 2%
  • Female Genital Disorders‡Þ 2%
  • Palpitation 2%
  • Vasodilation 2%
More Paxil side effects »
  • Abdominal pain 1%
  • Problems with orgasm 2%
  • Constipation 2%
  • Indigestion 2%
  • Decreased appetite 2%
  • Decrease libido 2%
  • Sinus infection 1%
  • Impotence 3%
  • Increased sweating 3%
  • Dizziness 2%
More Lexapro side effects »
  • Fever 1%
  • Vasodilatation 1%
  • Weight loss 1%
  • Thinking abnormal 1%
  • Abnormal vision 1%
  • Flatulence 1%
  • Vomiting 1%
  • Yawn 3%
  • Pruritus 1%
  • Libido decreased 3%
More Prozac side effects »
  • Chest pain 1%
  • Trauma 1%
  • Pressure/hypertension 2%
  • Tachycardia 2%
  • Libido decreased 2%
  • Agitation 2%
  • Confusion 1%
  • Thinking abnormal 1%
  • Taste perversion 2%
  • Tinnitus 2%
More Effexor side effects »
How it works
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
Trintellix (Vortioxetine) is a selective serotonin reuptake inhibitor (SSRI) that also directly effects the serotonine recpetors. It increases amount and effect of serotonine in the brain, which regulates mood.Cymbalta (Duloxetine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulates mood.Wellbutrin (Bupropion) is an atypical antidepressant. Researchers don't know exactly how it works, but it seems to change dopamine and norepinephrine activity in the brain, which regulate mood.Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Zoloft (Sertraline) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases the activity of serotonin in the brain, which regulates mood.Remeron (mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.Paxil (Paroxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin in the brain which regulates mood.Prozac (Fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Effexor (Venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulate mood.
Type of medication
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
No lower cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Pill
  • Oral solution
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
  • Pill
  • Extended release tablet
  • Liquid
  • Pill
  • Liquid
  • Pill
  • Delayed release capsule
  • Liquid
  • Pill
  • Extended release
Used for
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
Risk factors for serious side effects
TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    Coming soon.
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Cymbalta (Duloxetine) suddenly
    • History of high blood pressure
    • Taking other blood-thinning drugs
    Detailed Cymbalta (Duloxetine) risks & warnings »
    • Age 24 years or younger
    • History of depression
    • History of bipolar disorder
    • At risk for bipolar disorder
    • Withdrawing from nicotine
    Detailed Wellbutrin (Bupropion) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • History of bipolar disorder
    • At risk for bipolar disorder
    • Stopping Celexa (Citalopram) suddenly
    Detailed Celexa (Citalopram) risks & warnings »
    • Under 24 years old
    • Interactions with other medications
    • Stopping Zoloft (Sertraline) suddenly
    • Taking with blood-thinning drugs
    • Elderly
    Detailed Zoloft (Sertraline) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • History of heart problems
    • History of liver problems
    • Higher dose
    Detailed Remeron (mirtazapine) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Paxil (Paroxetine) suddenly
    • Taking other blood-thinning drugs
    • History of bipolar disorder
    Detailed Paxil (Paroxetine) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Lexapro (escitalopram) suddenly
    • Taking blood thinners
    • Bipolar disorder
    Detailed Lexapro (escitalopram) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Prozac (Fluoxetine) suddenly
    • History of heart problems
    • History of liver problems
    Detailed Prozac (Fluoxetine) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Effexor (Venlafaxine) suddenly
    • History of high blood pressure
    • Taking other blood-thinning drugs
    Detailed Effexor (Venlafaxine) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    • Make sure it doesn't interact with your other medications.
    • Higher likelihood of interaction with other medications.
    No interactions related info.No interactions related info.No interactions related info.
    • It interacts with St. John's Wort and Tryptophan.
    • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
    No interactions related info.
    • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
    No interactions related info.No interactions related info.
    Alcohol
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No alcohol related info.No alcohol related info.
    • Has a higher risk of causing seizures, especially if you have a seizure disorder, eating disorder, or if you drink alcohol. So, it's not a good medication if you drink a lot.
    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
    Food
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    • Take with food and/or at night to lessen stomach issues, such as nausea, diarrhea, gas.
    • Take with food to avoid upset stomach.
    No food related info.
    • Take with food to avoid upset stomach.
    No food related info.No food related info.
    • Take with food to avoid upset stomach.
    No food related info.
    • Take in the morning with food to avoid side effects.
    No food related info.
    Kidneys and liver
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No kidneys and liver related info.
    • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
    • Wellbutrin (Bupropion) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose to prevent increased risk for side effects.
    • Not a good option for you if you have heart or liver problems.
    No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
    Pain
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No pain related info.
    • Full effects in 8 to 12 weeks for mood, 2 weeks for pain.
    No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
    Sex
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No sex related info.No sex related info.No sex related info.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    No sex related info.No sex related info.No sex related info.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    Sleep
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No sleep related info.No sleep related info.No sleep related info.No sleep related info.
    • Zoloft (Sertraline) may increase the risk of low sodium levels in the blood (hyponatremia). Watch out for symptoms including headache, difficulty concentrating, memory problems, confusion, weakness, and unsteadiness, which may lead to falls. Talk to a doctor right away before developing more serious symptoms, such as hallucination, fainting, coma, and death.
    • Causes less drowsiness than other antidepressants.
    • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
    • Can help you fall asleep if you have trouble sleeping.
    • Makes you more tired than other antidepressants.
    • It causes drowsiness, so it's good for people who have trouble sleeping.
    No sleep related info.No sleep related info.No sleep related info.
    Weight
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    No weight related info.No weight related info.
    • It's less likely to cause weight gain than other antidepressants.
    • Can cause minor weight gain (1 to 5 pounds).
    No weight related info.
    • Remeron (mirtazapine) can raise your appetite and cause you to gain weight. Remeron (mirtazapine) can also raise your cholesterol.
    • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
    • Good option if you are underweight or frail, because it can help you gain weight.
    • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
    • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
    • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
    • Can cause a small weight gain of 1-5 pounds.
    No weight related info.No weight related info.
    Upsides and benefits
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    • Relieves depression symptoms.
    • May improve memory.
    • Possibly less side effect on sex drive/enjoyment compared to other antidepressants.
    • Works differently than other serotonine modifying antidepressants.
    • Effective at relieving depression and anxiety symptoms.
    • Lowers relapse rates for depression.
    • Can relieve some types of chronic pain. Might be particularly good at pain relief for people who are also depressed.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at relieving depression symptoms.
    • Causes fewer sexual side effects than other antidepressants. Can actually boost sex drive for some people.
    • Can be taken with other antidepressants to counteract their sexual side effects.
    • Has some stimulant effects, so it can be energizing.
    • Can help with ADHD symptoms.
    • Also used to suppress appetite and help you quit smoking.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at relieving depression and anxiety symptoms.
    • Causes less sleepiness compared to other antidepressants.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at lowering symptoms and relapse rates of depression and anxiety disorders.
    • Causes less drowsiness than other antidepressants.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at relieving some depression symptoms.
    • Starts to work more quickly than most antidepressants.
    • Can help you fall asleep if you have trouble sleeping.
    • Can also help relieve anxiety.
    • Good option if you are underweight or frail, because it can help you gain weight.
    • Available as a generic.
    • Effective at relieving depression and anxiety symptoms.
    • Lowers relapse rates of depression and anxiety disorders, including OCD, panic disorder, social anxiety disorder, and generalized anxiety disorder.
    • It causes drowsiness, so it's good for people who have trouble sleeping.
    • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at relieving depression and anxiety symptoms.
    • Lowers the likelihood that your depression will come back.
    • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
    • Effective at relieving depression and anxiety symptoms.
    • Lowers relapse rates of depression and bulimia nervosa.
    • Causes less sleepiness than other antidepressants.
    • It's more energizing than other antidepressants, so it's good for people who have low energy.
    • It has been used to treat depression for a long time, so there's a lot of information available about how it works and how safe it is.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Effective at relieving depression and anxiety symptoms.
    • Lowers relapse rates of depression.
    • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    • Might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood. Many other antidepressants affect only serotonin, but not norepinephrine too.
    Downsides and risks
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    • Likely expensive since insurance may not cover it.
    • Stomach issues, particularly nausea, can be persistant for some people.
    • Higher likelihood of interaction with other medications.
    • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
    • Not the best option for people with high blood pressure.
    • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Wellbutrin (Bupropion) can be stimulating, so it can cause anxiety or insomnia the first few days you're taking it.
    • Generally not as good as other antidepressants for people who have anxiety.
    • It's less likely to cause weight gain than other antidepressants.
    • Has a higher risk of causing seizures, especially if you have a seizure disorder, eating disorder, or if you drink alcohol. So, it's not a good medication if you drink a lot.
    • It contains the same ingredient as a medication that helps you to stop smoking, (Zyban), so these two meds can't be used together.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Can cause minor weight gain (1 to 5 pounds).
    • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
    • Not a good option for you if you have heart or liver problems.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • More likely to cause diarrhea than other antidepressants.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Makes you more tired than other antidepressants.
    • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
    • Can cause more sexual side effects like low libido and an inability to orgasm or ejaculate than most antidepressants.
    • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
    • Can harm an unborn child, so you can't take it if you're pregnant.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than age 24.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Can cause a small weight gain of 1-5 pounds.
    • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
    • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Can increase feelings of anxiety or cause headaches during the first few weeks of taking it. These effects should go away over time.
    • More likely than other antidepressants to interact with other medications you're taking.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
    • Not the best option for people with high blood pressure.
    • Overdosing on this medication could be fatal.
    • It's more likely to cause nausea and vomiting or make you feel sick if you miss a dose than other antidepressants. Also causes more sleepiness than others.
    • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    Tips from our pharmacists for people taking the medication
    TrintellixCymbaltaWellbutrinCelexaZoloftRemeronPaxilLexaproProzacEffexor
    • Take with food and/or at night to lessen stomach issues, such as nausea, diarrhea, gas.
    • Stomach disturbances usually happen withine the first 1-2 weeks and improves over time, but can persist for some people.
    • Make sure it doesn't interact with your other medications.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • Don't stop taking the medicine suddenly to avoid withdrawl symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Take with food to avoid upset stomach.
    • Full effects in 8 to 12 weeks for mood, 2 weeks for pain.
    • Stop taking slowly to avoid withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Wellbutrin (Bupropion) makes you energized, so take it in the morning to avoid difficulty sleeping later that night.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • There are no sexual side effects from this medication.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • The extended-release tablet shell can show up unchanged in your stool, but don't worry since the medication was still absorbed by your body.
    • Take with food to avoid upset stomach.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • It interacts with St. John's Wort and Tryptophan.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
    • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
    • You should not abruptly stop Remeron (mirtazapine) as this could cause serious side effects.
    • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
    • Remeron (mirtazapine) should be protected from light. Keep it in it's original package until ready to use.
    • Remeron (mirtazapine) can cause dry mouth. Try using sugar-free gum or candy to help with dry mouth.
    • Take with food to avoid upset stomach.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • The controlled-release (CR) tablet can cause less nausea than other forms.
    • Don’t crush, break, or chew the Paxil (Paroxetine) controlled-release tablet or the Pexeva film-coated tablets.
    • It’s best to take Paxil (Paroxetine) in the morning, except Brisdelle, which can be taken at bedtime.
    • Don't suddenly stop taking DRUG NAME. Talk to your doctor about how to slowly go down in your dose to avoid withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Like other SSRI medications, it could take up to 8 weeks to see the full effects of Lexapro (escitalopram).
    • Take Lexapro (escitalopram) in the morning since it can keep you up if you take it at night.
    • Take in the morning with food to avoid side effects.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
    • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
    • Extended-release capsules should be swallowed whole. If you can’t swallow pills, open the capsule, sprinkle it on a spoonful of applesauce and then swallow it without chewing.
    • Stop taking it slowly to avoid getting withdrawal symptoms.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    Learn more
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