Prescription onlyNo lower cost generic available

Truvada

(Emtricitabine / Tenofovir)

Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Tips from users and pharmacists

Works with other medicines to treat HIV infection.

Skip Upsides & Downsides section. Skip to side effects section.
Prescription onlyNo lower cost generic available

Our bottom line

Truvada (Emtricitabine / Tenofovir) is a popular combination medicine that has two drugs with the same mechanism of action to treat and prevent HIV infection.

Upsides

  • First-line treatment for preventing HIV infection in combination with other HIV medications.
  • Only has to be taken once a day.
  • Truvada (Emtricitabine / Tenofovir) prevents and treats HIV infection.
  • Used for preventing HIV infection in case you've been accidentally exposed or if you're in danger of being exposed.

Downsides

  • Has to be taken at the same time every day or your body can become resistant to the medication.
  • Can't be taken on its own to treat HIV.
  • Can cause unusual dreams, or kidney or liver damage.
  • Can't be taken with any drugs containing lamivudine since both are so similar to each other.
  • Truvada (Emtricitabine / Tenofovir) is removed from the body by the kidneys, so the dose of Truvada (Emtricitabine / Tenofovir) needs to be lowered if you have any kidney problems.

Save on your next Truvada (Emtricitabine / Tenofovir) prescription

Get the lowest price for your medication, even if you have insurance.

What to expect when you take Truvada (Emtricitabine / Tenofovir) for Treat HIV

Skip what to expect section. Skip to Risks & Warnings section.
Tips from our pharmacists
  • Since Truvada (Emtricitabine / Tenofovir) is only taken once a day, try taking it at the same time as your other HIV medications.
  • If being used for kids, the dose of Truvada (Emtricitabine / Tenofovir) will continue to change as they grow, so keep in touch with their doctor.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking Truvada (Emtricitabine / Tenofovir) and report them to your doctor.
  • Practice safe sex while taking Truvada (Emtricitabine / Tenofovir) since the medication will not stop you from passing HIV to other people.
Skip side effects sections. Skip to What to Expect and Pharmacists Tips section.

Side effects for Truvada (Emtricitabine / Tenofovir)

From clinical trials of Truvada / HIV infection treatment (Taken with efavirenz)  ( 257)

  • DiarrheaDiarrhea9% for Truvada vs.0% for placebo
  • Low mood disorderLow mood disorder9% for Truvada vs.0% for placebo
  • FatigueFatigue9% for Truvada vs.0% for placebo
  • NauseaNausea9% for Truvada vs.0% for placebo
  • Sinus inflammationSinus inflammation8% for Truvada vs.0% for placebo
  • Ear, nose, or throat infectionEar, nose, or throat infection8% for Truvada vs.0% for placebo
  • DizzinessDizziness8% for Truvada vs.0% for placebo
  • RashRash7% for Truvada vs.0% for placebo
  • HeadacheHeadache6% for Truvada vs.0% for placebo
  • Sleep difficultySleep difficulty5% for Truvada vs.0% for placebo

Risks and Warnings for Truvada (Emtricitabine / Tenofovir)

Skip Risks and Warnings section. Skip to Tips section.
  • Truvada (Emtricitabine / Tenofovir) can cause high lactic acid levels in the blood, which will lead to liver damage. This is very rare, but talk to your doctor immediately if you have unexplained nausea, vomiting, abdominal pain, or weakness.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Truvada (Emtricitabine / Tenofovir)

Final section. Do you want to return to drug navigation?
The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Food
  • I take it with breakfast. The main side effect I noticed was cramping, which comes and goes, and seems to be less of a problem if I stay hydrated.
Kidneys and liver
  • Upsides and downsides from our pharmacists
  • Can cause unusual dreams, or kidney or liver damage.
  • Truvada (Emtricitabine / Tenofovir) is removed from the body by the kidneys, so the dose of Truvada (Emtricitabine / Tenofovir) needs to be lowered if you have any kidney problems.
  • Risks from our pharmacists
  • People on Truvada (Emtricitabine / Tenofovir) have reported kidney damage, which can be made worse if you take high doses of anti-inflammatory drugs called NSAIDs (Motrin/Advil, Aleve, Mobic, Voltaren, etc.). Call your doctor if you develop bone pain, pain in your arms or legs, or pain or weakness in your muscles.
  • I got the "monster" at 23.It took me about 10yrs to realize I wasn't going to die.At 33,I was not in good shape. My doctor prescribed Truvada 1 tab 245mg along with 2 tabs 250mg each of Kaletra in the PM, then 2 more Kaletras in the AM.Those Kaletras are horse-pills!I am 98lbs and 5ft tall.By the first year,I was undetectable.I party,but to my surprise,kidneys/liver just fine.I HAVE noticed bone/muscle deterioration in my arms this 9th yr.Take only for 7yrs max. Then switch.
Sex
  • Tips from our pharmacists
  • Practice safe sex while taking Truvada (Emtricitabine / Tenofovir) since the medication will not stop you from passing HIV to other people.
  • I first started PrEP as an added safety measure, no side effects except massive improvement in my ability to relax and enjoy sex with my boyfriend.
  • Incredible and effective option for remaining HIV negative while sexually active with partners.
  • I had a few headaches the first couple of days but they subsided quickly. No side effects now, just a considerably more relaxed sex life.
Sleep
  • Take it before going to sleep to avoid possible side effects