Prescription onlyClass: Musculoskeletal



Prescription onlyClass: Musculoskeletal
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Prevents gout attacks.

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Our bottom line

Uloric (Febuxostat) is a once a day medication for chronic gout, but it takes a few weeks to kick in.


  • In one clinical trial, Uloric (Febuxostat) was shown to decrease uric acid to normal levels in over half of the people taking it. It worked better than Zyloprim (allopurinol).
  • You only need to take Uloric (Febuxostat) once a day.
  • Uloric (Febuxostat) can be used in people with mild to moderate kidney disease.


  • Can increase the amount of gout attacks in the first few weeks.
  • You need to drink a lot of fluids while taking this to prevent kidney stones from forming.
  • While taking Uloric (Febuxostat), you'll have to get your blood checked often.
  • Doesn't come in a generic version.
How it works

Uloric (Febuxostat) is an antigout xanthine oxidase inhibitor. It decreases the build up of uric acid, the enzyme that causes gout.

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Side effect rates for Uloric (febuxostat)

891 From clinical trials of Uloric / Gout (40 mg)
  • Liver function abnormalities

Risks and Warnings for Uloric (febuxostat)

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  • An increase in gout flares is commonly seen when first starting Uloric (Febuxostat). This is due to the movement of uric acid that is built up in your body. While your body gets used to Uloric (Febuxostat), an additional medication can help prevent these flare-ups.

Common concerns from people taking Uloric (febuxostat)

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  • To help prevent attacks, avoid beer, sugary drinks, and foods like red meat, seafood, turkey, asparagus, cauliflower, spinach, and mushrooms.
Kidneys and liver
  • Uloric (Febuxostat) can be used in people with mild to moderate kidney disease.