Prescription or OTCLower-cost generic available

Unisom Sleeptabs

(Doxylamine)

  • Pill
  • Chewable tablet
  • Liquid
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Treats allergy symptoms and helps you sleep.

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Prescription or OTCLower-cost generic available

Our pharmacists’ bottom line

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

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  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).

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Side effects for Unisom Sleeptabs (Doxylamine)

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These are side effects of Unisom Sleeptabs (Doxylamine) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Unisom Sleeptabs (Doxylamine) for Insomnia

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Tips from our pharmacists
  • Starts working in 30 minutes.
  • Unisom Sleeptabs (Doxylamine) makes you tired, so take it before you go to sleep.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
  • Unisom comes in two different generic forms, doxylamine (Unisom SleepTabs) and diphenhydramine (other Unisom products). Both are antihistamines that help you sleep.

Risks and Warnings for Unisom Sleeptabs (Doxylamine)

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    • Higher risk if:
    • Using other drugs with similar ingredients

    There are a variety of over-the-counter medications with similar ingredients as Unisom Sleeptabs (Doxylamine). It's not safe to use more than one medication containing doxylamine (the ingredient in Unisom Sleeptabs (Doxylamine)) or diphenhydramine (also known as Benadryl) at the same time. Read package labels carefully to make sure you take the right dose of these medications.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Unisom Sleeptabs (Doxylamine)

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The FDA category for this medication is N. It is advised that you: Unknown
Pregnancy
Alcohol
  • Upsides and downsides from our pharmacists
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • Tips from our pharmacists
  • Don't take it with alcohol or other drugs that make you sleepy.
Sleep
  • Upsides and downsides from our pharmacists
  • Shouldn't be used unless you have a full night to sleep.
  • Has fewer side effects than prescription sleep aid medications.
  • Not habit-forming like other sleep aids can be.
  • Tips from our pharmacists
  • Unisom Sleeptabs (Doxylamine) makes you tired, so take it before you go to sleep.
  • Unisom comes in two different generic forms, doxylamine (Unisom SleepTabs) and diphenhydramine (other Unisom products). Both are antihistamines that help you sleep.
  • Risks from our pharmacists
  • People age 65 years and older have a higher risk of side effects from taking antihistamine medications like Unisom Sleeptabs (Doxylamine). Watch for changes in vision, severe dry mouth, trouble urinating, or constipation. The drowsiness caused by Unisom Sleeptabs (Doxylamine) can make you "unsteady" on your feet, leading to a higher chance of falls.