Over-the-counterLower-cost generic availableClass: Respiratory

Unisom SleepgelsAlternatives

(diphenhydramine)

Over-the-counterLower-cost generic availableClass: Respiratory
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Compare Unisom Sleepgels (diphenhydramine) to alternatives

These medications are comparable to Unisom Sleepgels (diphenhydramine) or used for similar purposes.

Unisom Sleepgels
(diphenhydramine)

Nasacort Aq
(triamcinolone)

Zyrtec D
(cetirizine / pseudoephedrine)

Sudafed
(pseudoephedrine)

Claritin
(loratadine)

Claritin D
(loratadine / pseudoephedrine)

Flonase
(fluticasone)

Allegra
(fexofenadine)

Nasonex
(mometasone)

Allegra D
(pseudoephedrine / fexofenadine)

Rhinocort Aqua
(budesonide)

Zyrtec
(cetirizine)

Treats allergy symptoms and helps you sleep. Unisom Sleepgels (Diphenhydramine) is a good over-the-counter medication for nighttime allergies.Relieves allergy symptoms. Nasacort Aq (Triamcinolone) is the only medication in its class available over the counter for treating stuffy and runny nose due to allergies. You have to use it every day for it to work.Relieves congestion and allergy symptoms. Zyrtec D (Cetirizine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.Treats allergy symptoms. Claritin (Loratadine) is a once-daily allergy relief medication that doesn't make you feel sleepy.Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.Relieves allergy symptoms. Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.Treats allergy symptoms. Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.Relieves allergy symptoms. Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.Treats allergy symptoms and congestion. Allegra D (Pseudoephedrine / Fexofenadine) is a combination allergy medicine that's useful if you have congestion and runny nose.Relieves nasal allergy symptoms. Rhinocort Aqua (Budesonide) is a steroid nasal spray that works best when used regularly for your nasal allergy symptoms.Treats allergy symptoms. Zyrtec (Cetirizine) is a once-daily allergy relief medication that won't make you feel too sleepy.
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Reviews & ratings
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Unisom Sleepgels (diphenhydramine)?
Worth itNot sureNot worth it
Reviews for Nasacort Aq (triamcinolone)
67%
-33% worse vs. Unisom Sleepgels (diphenhydramine)
39%
-61% worse vs. Unisom Sleepgels (diphenhydramine)
10%
-10% worse vs. Unisom Sleepgels (diphenhydramine)
328 reviews
Have you used Nasacort Aq (triamcinolone)?
Worth itNot sureNot worth it
Reviews for Zyrtec D (cetirizine / pseudoephedrine)
75%
-25% worse vs. Unisom Sleepgels (diphenhydramine)
43%
-57% worse vs. Unisom Sleepgels (diphenhydramine)
9%
-9% worse vs. Unisom Sleepgels (diphenhydramine)
927 reviews
Have you used Zyrtec D (cetirizine / pseudoephedrine)?
Worth itNot sureNot worth it
Reviews for Sudafed (pseudoephedrine)
82%
-18% worse vs. Unisom Sleepgels (diphenhydramine)
45%
-55% worse vs. Unisom Sleepgels (diphenhydramine)
6%
-6% worse vs. Unisom Sleepgels (diphenhydramine)
1740 reviews
Have you used Sudafed (pseudoephedrine)?
Worth itNot sureNot worth it
Reviews for Claritin (loratadine)
74%
-26% worse vs. Unisom Sleepgels (diphenhydramine)
38%
-62% worse vs. Unisom Sleepgels (diphenhydramine)
6%
-6% worse vs. Unisom Sleepgels (diphenhydramine)
1517 reviews
Have you used Claritin (loratadine)?
Worth itNot sureNot worth it
Reviews for Claritin D (loratadine / pseudoephedrine)
69%
-31% worse vs. Unisom Sleepgels (diphenhydramine)
39%
-61% worse vs. Unisom Sleepgels (diphenhydramine)
8%
-8% worse vs. Unisom Sleepgels (diphenhydramine)
1527 reviews
Have you used Claritin D (loratadine / pseudoephedrine)?
Worth itNot sureNot worth it
Reviews for Flonase (fluticasone)
72%
-28% worse vs. Unisom Sleepgels (diphenhydramine)
43%
-57% worse vs. Unisom Sleepgels (diphenhydramine)
7%
-7% worse vs. Unisom Sleepgels (diphenhydramine)
890 reviews
Have you used Flonase (fluticasone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Allegra (fexofenadine)?
Worth itNot sureNot worth it
Reviews for Nasonex (mometasone)
68%
-32% worse vs. Unisom Sleepgels (diphenhydramine)
39%
-61% worse vs. Unisom Sleepgels (diphenhydramine)
8%
-8% worse vs. Unisom Sleepgels (diphenhydramine)
675 reviews
Have you used Nasonex (mometasone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Allegra D (pseudoephedrine / fexofenadine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Rhinocort Aqua (budesonide)?
Worth itNot sureNot worth it
Reviews for Zyrtec (cetirizine)
76%
-24% worse vs. Unisom Sleepgels (diphenhydramine)
47%
-53% worse vs. Unisom Sleepgels (diphenhydramine)
7%
-7% worse vs. Unisom Sleepgels (diphenhydramine)
1232 reviews
Have you used Zyrtec (cetirizine)?
Worth itNot sureNot worth it
Side effects
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec

We haven’t found good data for Unisom SleepGels side effects.

FDA side effect reports for Unisom SleepGels »
  • Sore throat 1%
  • Nosebleed 3%
  • Flu syndrome 2%
  • Bronchitis 2%
  • Indigestion 2%
  • Tooth disorder 2%
  • Headache 2%
  • Throat pain 2%
  • Common cold 1%
More Nasacort AQ side effects »

We haven’t found good data for Zyrtec D side effects.

FDA side effect reports for Zyrtec D »

We haven’t found good data for Sudafed side effects.

FDA side effect reports for Sudafed »

We haven’t found good data for Claritin side effects.

FDA side effect reports for Claritin »

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »
  • Asthma symptoms 4%
  • Nosebleed 1%
  • Nausea/vomiting 3%
  • Cough 1%
  • Blood in mucus 2%
  • Bronchitis 2%
  • Abdominal pain 2%
More Flonase side effects »
  • Menstrual cramps 2%
  • Headache 3%
  • Back pain 2%
  • Cough 3%
  • Ear, nose, or throat infection 2%
  • Fever 1%
  • Middle ear inflammation 2%
  • Runny nose 1%
More Allegra side effects »
  • Headache 4%
  • Viral infection 3%
  • Sore throat 2%
  • Nosebleed 5%
  • Coughing 1%
  • Ear, nose, or throat infection 4%
  • Menstrual cramps 2%
  • Musculoskeletal pain 2%
  • Sinus inflammation 2%
  • Joint pain 4%
More Nasonex side effects »
  • Headache 3%
  • Back pain 2%
  • Sleep difficulty 13%
  • Nausea 7%
  • Adverse effects 4%
  • Indigestion 3%
  • Dry mouth 3%
  • Dizziness 2%
  • Agitation 2%
More Allegra D side effects »
  • Nosebleed 3%
  • Sore throat 1%
  • Bronchospasm 1%
  • Coughing 2%
  • Nasal irritation 2%
More Rhinocort Aqua side effects »

We haven’t found good data for Zyrtec side effects.

FDA side effect reports for Zyrtec »
How it works
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
Unisom Sleepgels (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.Nasacort Aq (Triamcinolone) is a nasal steroid. It works directly in your nose to help reduce swelling and inflammation from allergies.Zyrtec D (Cetirizine / Pseudoephedrine) is a combination medicine for allergies. Cetirizine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Sudafed (Pseudoephedrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.Claritin (Loratadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. Antihistamines can also make you sleepy, but Loratadine is a low-drowsiness version.Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Flonase (Fluticasone) is a nasal steroid. It works directly in your nose to reduce swelling and inflammation caused by allergies.Allegra (Fexofenadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions.Nasonex (Mometasone) is a topical steroid. It works directly where it's applied to help reduce swelling and inflammation in your nose.Allegra D (Pseudoephedrine / Fexofenadine) is a combination medicine that relieves allergy symptoms. Fexofenadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itching. Pseudoephedrine (a decongestant) clears your sinuses.Rhinocort Aqua (Budesonide) is a steroid nasal spray that works directly in your nose to reduce swelling and allergy symptoms.Zyrtec (Cetirizine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. Antihistamines can also make you sleepy, but Zyrtec is a low-drowsiness version.
Type of medication
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
Over-the-counter
Prescription or OTC
Prescription or OTC
Prescription or OTC
Prescription or OTC
Prescription or OTC
Prescription or OTC
Prescription or OTC
Prescription only
Prescription or OTC
Prescription only
Prescription or OTC
Available as
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
  • Pill
  • Chewable tablet
  • Liquid
  • Nasal spray
  • Extended release
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Chewable tablet
  • Orally disintegrating tablet
  • Liquid
  • Extended release
  • Nasal spray
  • Pill
  • Dissolving tablet
  • Liquid
  • Nasal spray
  • Extended release
  • Nasal spray
  • Pill
  • Liquid capsule
  • Dissolving tablet
  • Liquid
Used for
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
Risk factors for serious side effects
Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
  • Using other drugs with the same ingredients
  • Age 65 years or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Children age 6 years and younger
  • Enlarged prostate
  • History of bladder problems
  • Glaucoma
  • Nursing mothers
Detailed Unisom Sleepgels (diphenhydramine) risks & warnings »
  • Long-term use
  • Surgery or trauma to the nose or sinuses
  • Exposure to immunizable diseases (chickenpox and measles)
  • Exposure to tuberculosis
  • Long-term use
  • Switching from oral or injectable steroids to inhaled, especially if used long term
  • Using other inhaled steroids with Nasacort Aq (Triamcinolone)
  • Long-term use
  • Taking more than recommended dose
Detailed Nasacort Aq (triamcinolone) risks & warnings »
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
    • Age 65 years or older
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Current kidney disease
    • Current liver disease
    Detailed Zyrtec D (cetirizine / pseudoephedrine) risks & warnings »
    • History of high blood pressure
    • History of heart problems
    • Age 65 years or older
    • History of seizures
    • Women of childbearing age
    Detailed Sudafed (pseudoephedrine) risks & warnings »
      • Age 65 or older
      • Taking with alcohol
      • Taking other medicines that make you less alert
      • History of phenylketonuria (PKU)
      Detailed Claritin (loratadine) risks & warnings »
      • History of high blood pressure
      • History of heart problems
      • Age 65 or older
      • History of seizure
      • Women of childbearing age
        • Age 65 years or older
        • Taking with alcohol
        • Taking other medicines that make you less alert
        • History of phenylketonuria (PKU)
        Detailed Claritin D (loratadine / pseudoephedrine) risks & warnings »
        • Switching from oral or injectable steroids to inhaled, especially if used long term
        • Using other inhaled steroids with Flonase (Fluticasone)
          • Long-term use
          • Taking more than recommended dose
          • Long-term use
          • Exposure to immunizable diseases (chickenpox and measles)
          • Exposure to tuberculosis
          • Surgery or trauma to the nose or sinuses
          • Long-term use
          Detailed Flonase (fluticasone) risks & warnings »
          • Taking with alcohol
          • Taking other medicines that make you less alert
          • History of phenylketonuria (PKU)
          Detailed Allegra (fexofenadine) risks & warnings »
          • Long-term use
          • Long-term use
          • Surgery or trauma to the nose or sinuses
          • Long-term use
          • Exposure to immunizable diseases (chickenpox and measles)
          • Exposure to tuberculosis
          • Long-term use
          • Taking more than recommended dose
          Detailed Nasonex (mometasone) risks & warnings »
          • Taking with alcohol
          • Taking other medicines that make you less alert
          • History of high blood pressure
          • History of heart problems
          • Age 65 or older
          • History of seizure
          • Women of childbearing age
          Detailed Allegra D (pseudoephedrine / fexofenadine) risks & warnings »
          • Long-term use
          • Surgery or trauma to the nose or sinuses
          • Long-term use
          • Untreated infections
          • Long-term use
          • Long-term use
          • Long-term use
          • Taking more than recommended dose
          Detailed Rhinocort Aqua (budesonide) risks & warnings »
            • Age 65 or older
            • Taking with alcohol
            • Taking other medicines that make you less alert
            • Current kidney disease
            • Current liver disease
            Detailed Zyrtec (cetirizine) risks & warnings »
            Pregnancy

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

            Price
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            No price related info.No price related info.No price related info.No price related info.No price related info.No price related info.No price related info.No price related info.No price related info.No price related info.
            • It's good for 120 sprays, but there isn't a counter to help you keep track of sprays.
            No price related info.
            Alcohol
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            • Don't take it with alcohol or other drugs that make you sleepy.
            No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
            Food
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            No food related info.No food related info.No food related info.No food related info.
            • Claritin (Loratadine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
            • Claritin D (Loratadine / Pseudoephedrine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
            No food related info.
            • Some forms of Allegra (Fexofenadine) contain aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, check to see which products you can use.
            No food related info.No food related info.No food related info.No food related info.
            Kidneys and liver
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            No kidneys and liver related info.No kidneys and liver related info.
            • People with kidney or liver disease may need to take a lower dose of Zyrtec D (Cetirizine / Pseudoephedrine) to prevent overdose. Talk with your doctor to be sure you are using the correct dose.
            No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
            • The dose needs to be adjusted for people with kidney problems.
            No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
            • People with kidney or liver disease may need to take a lower dose of Zyrtec (Cetirizine) to prevent overdose. Talk with your doctor to be sure you are using the correct dose.
            Pain
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
            • Long-term use of Flonase (Fluticasone) can increase your chances of getting thrush in the nose and throat. Your doctor will check your nose and throat if you have to be on this medication for a long time. Also, tell your doctor if you notice pain in the nose and throat with redness and white patches.
            No pain related info.
            • Long-term use of Nasonex (Mometasone) can increase your chances of getting thrush in the nose and throat. Your doctor will check your nose and throat if you have to be on this medication for a long time. Also, tell your doctor if you notice pain in the nose and throat with redness and white patches.
            No pain related info.No pain related info.No pain related info.
            Sleep
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            • Unisom Sleepgels (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
            No sleep related info.
            • The antihistamine (Cetirizine) in Zyrtec D (Cetirizine / Pseudoephedrine) causes less drowsiness than other medications like Benadryl.
            • The antihistamine (Cetirizine) can cause more drowsiness than similar antihistamines, like Allegra D (which contains Fexofenadine) and Claritin D (which contains Loratadine).
            • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
            • It can affect the quality of your sleep, so you can't take it too close to going to bed.
            • Can make you feel sleepy, so take it at bedtime if needed.
            • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
            No sleep related info.
            • Won't make you feel drowsy like some antihistamine medicines.
            • Can make you feel dizzy or sleepy, so you can take it at bedtime.
            No sleep related info.
            • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
            • Doesn't make you drowsy or dizzy.
            • Can make you feel sleepy, so take it at bedtime if needed.
            Upsides and benefits
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            • Unisom Sleepgels (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
            • It can provide quick relief of allergy symptoms for both kids and adults.
            • It makes you sleepy, so it'll help if your allergies are bothering you at night.
            • The effects wear off in 4 to 6 hours, so side effects don't last that long.
            • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
            • Available over the counter without a prescription.
            • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
            • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
            • The antihistamine (Cetirizine) in Zyrtec D (Cetirizine / Pseudoephedrine) causes less drowsiness than other medications like Benadryl.
            • The decongestant (Pseudoephedrine) in Zyrtec D (Cetirizine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
            • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
            • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
            • It's available without a prescription, unlike other strong allergy medicines.
            • One of the best over-the-counter options to clear stuffy nose and help you breathe better.
            • Clears nasal congestion better than other decongestants like phenylephrine.
            • Can be helpful in relieving congestion-related headaches and pressure in your ears.
            • Available in regular and extended release forms.
            • Relieves allergy symptoms like sneezing and runny nose just as well as other antihistamines, but with less sedation (drowsiness).
            • Also treats hives and itchy skin.
            • Side effects are rare and usually mild.
            • Available over the counter without a prescription.
            • Comes as a tablet, liquid, or quick-dissolving tablet.
            • Can provide quick relief of allergy symptoms for both kids and adults.
            • Okay to take with most other medications because it doesn't have many interactions.
            • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
            • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
            • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
            • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
            • It's available without a prescription, unlike other strong allergy medicines.
            • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
            • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
            • Can be used as needed to help control symptoms in people age 13 years or older.
            • Available as a generic medication.
            • Relieves allergy symptoms, like sneezing, runny nose, and itching.
            • Approved to be used in kids and adults age 6 months and older.
            • Won't make you feel drowsy like some antihistamine medicines.
            • Available over-the-counter without a prescription.
            • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
            • It's okay to take with most other medications since it has very few interactions.
            • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
            • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
            • Can be used as needed to help control symptoms in people age 13 years or older.
            • Available as a generic, which is cheaper.
            • Available without a prescription in the drugstore.
            • It has two medications that work in different ways to help relieve nasal symptoms.
            • The antihistamine (fexofenadine) is useful for relieving itchy eyes, runny nose, or constant sneezing.
            • The decongestant (pseudoephedrine) is very good at relieving congestion.
            • Rhinocort Aqua (Budesonide) lowers the number of nasal symptoms you'll get during allergy season.
            • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
            • Doesn't make you drowsy or dizzy.
            • Zyrtec (Cetirizine) works as well as other antihistamines to treat sneezing and runny nose, but causes less sedation.
            • Works well to also treat hives and itchy skin.
            • Zyrtec (Cetirizine) is available over the counter without a prescription.
            • It comes as a tablet, liquid, and quick-dissolving tablet.
            • It can provide quick relief of allergy symptoms for both kids and adults.
            • It's okay to take with most other medications because it has few drug interactions.
            • Most people don't get any side effects from Zyrtec (Cetirizine).
            Downsides and risks
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            • Unisom Sleepgels (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
            • You shouldn't drive after taking Unisom Sleepgels (Diphenhydramine) until you know how it affects you.
            • Talk to a pediatrician before giving Unisom Sleepgels (Diphenhydramine) to a child.
            • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleepgels (Diphenhydramine).
            • Don't use Unisom Sleepgels (Diphenhydramine) if you are breastfeeding.
            • Can't be used on as-needed basis. Must be taken every day.
            • Doesn't have a counter on it, so it can be hard to remember how many sprays are left.
            • Since the medicine in Nasacort Aq (Triamcinolone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
            • Needs to be primed before use and re-primed if not used for more than 2 weeks.
            • You can have more side effects when using combination pills than when using single-ingredient medications.
            • The antihistamine (Cetirizine) can cause more drowsiness than similar antihistamines, like Allegra D (which contains Fexofenadine) and Claritin D (which contains Loratadine).
            • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
            • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
            • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
            • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
            • Pseudoephedrine (a decongestant) can make your heart race or make you feel anxious and restless.
            • It can affect the quality of your sleep, so you can't take it too close to going to bed.
            • Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions.
            • Sudafed (Pseudoephedrine) isn't as effective after using it for more than 4 days straight.
            • Need to show a photo ID to buy it in the drugstore and there is a limit on how much you can buy each visit.
            • For some people, its effectiveness on treating allergies wears off over time.
            • Some people find that other more sedating antihistamines (like Zyrtec or Benadryl) are more effective for them.
            • If you have daily allergy symptoms, a prescription nasal steroid spray might be better for you long-term.
            • Not for kids under 2 years.
            • The Reditabs version contains aspartame (phenylalanine).
            • You can have more side effects when using combination pills than when using single-ingredient medications.
            • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
            • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
            • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
            • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
            • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
            • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
            • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
            • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
            • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
            • The dose needs to be adjusted for people with kidney problems.
            • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
            • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
            • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
            • Has more side effects than Allegra since it has pseudoephedrine in it.
            • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
            • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
            • You must show a photo ID to buy this from behind the pharmacy counter. There's a maximum limit on how much you can buy in the pharmacy at a time.
            • Needs to be used everyday to work, so it can't be used as needed.
            • Can hace an unpleasant smell or taste.
            • It's good for 120 sprays, but there isn't a counter to help you keep track of sprays.
            • Can't be used in kids younger than age 6 years.
            • Need a prescription to get Rhinocort Aqua (Budesonide).
            • Although it works fast, its effectiveness wears off for some people over time.
            • Zyrtec (Cetirizine) can be slightly more sedating than Allegra or Claritin.
            • Some people find that other more sedating antihistamines, like Benadryl, are more effective for them than Zyrtec (Cetirizine).
            • If you have daily allergy symptoms, a prescription nasal steroid spray might be better for you long-term.
            Tips from our pharmacists for people taking the medication
            Unisom SleepGelsNasacort AQZyrtec DSudafedClaritinClaritin DFlonaseAllegraNasonexAllegra DRhinocort AquaZyrtec
            • Take Unisom Sleepgels (Diphenhydramine) at bedtime as needed if you're 12 years of age or older.
            • Unisom Sleepgels (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
            • Don't take it with alcohol or other drugs that make you sleepy.
            • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
            • Unisom comes in two different generic forms, doxylamine (Unisom SleepTabs) and diphenhydramine (other Unisom products). Both are antihistamines that help you sleep.
            • Use Nasacort Aq (Triamcinolone) once a day, following age-specific recommendations on how many sprays to use. Don't take more than prescribed.
            • Blow your nose before using.
            • Can cause thrush (a fungal infection) inside the nose and throat.
            • Can also cause nosebleeds, a sore throat, and headaches.
            • Needs to be used regularly during allergy season for it to work. It can take 1 to 2 weeks for the medicine to start working fully.
            • Check with your doctor or pharmacist on how to use the nasal spray the right way.
            • Shake well before using it. Before the first use, prime the bottle by spraying it until you see a fine mist.
            • Starts working in 30 minutes.
            • You need to show an ID to buy Zyrtec D (Cetirizine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
            • Don't cut, crush, or chew tablets; swallow them whole.
            • It's better to take Zyrtec D (Cetirizine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
            • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
            • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
            • Starts working in 30 minutes.
            • You need to show an ID to buy Sudafed (Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
            • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
            • Don't take Sudafed (Pseudoephedrine) too close to bedtime since it can keep you awake.
            • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
            • Talk to your doctor if your symptoms don't get better in 1 week.
            • Take it only once a day.
            • Starts working in a few hours.
            • Can make you feel sleepy, so take it at bedtime if needed.
            • Avoid possible side effects by drinking plenty of non-caffeinated liquids.
            • If you need to use it for more than a few weeks, talk with your doctor about trying a nasal steroid instead, which might work better for you long-term.
            • Using an antihistamine eye drop might work better to help itchy or watery eyes.
            • Starts working in 30 minutes.
            • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
            • Don't cut, crush, or chew tablets; swallow them whole.
            • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
            • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
            • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
            • It can take several days for Flonase (Fluticasone) to start working fully.
            • Don't take more of it than was prescribed for you.
            • Blow your nose before using Flonase (Fluticasone).
            • Can cause thrush (a fungal infection) inside the nose and throat.
            • Can also cause a headache, sore throat, or nosebleeds.
            • Starts working in 1 to 2 hours depending on what dosage form you're taking.
            • Works best when taken regularly, even before symptoms are expected to appear.
            • Can make you feel dizzy or sleepy, so you can take it at bedtime.
            • Follow age-specific dosing and don't take more than recommended.
            • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
            • Use Nasonex (Mometasone) once a day, following age-specific recommendations on how many sprays to use. Don't take more than prescribed.
            • Blow your nose before using.
            • Can cause thrush (a fungal infection) inside your nose and throat. Can also cause nosebleeds, a sore throat, and headaches.
            • Needs to be used regularly during allergy season for it to work. It can take 1 to 2 weeks for the medicine to start working fully.
            • Check with your doctor or pharmacist on how to use the nasal spray the right way.
            • Shake well before using it. Before the first use, prime the bottle by spraying it until you see a fine mist.
            • It works best if you have nasal congestion and a runny nose.
            • Take on an empty stomach, 1 hour before eating or 2 hours after eating.
            • Shouldn't be used in kids younger than 12 years old.
            • Avoid taking it close to bedtime to prevent trouble sleeping.
            • Can cause dizziness, headache, or a fast heartbeat.
            • Talk to your doctor if you have high blood pressure or kidney problems before using it.
            • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
            • Works best if used everyday. It takes about one week to start seeing the best results.
            • Check with your doctor or pharmacist to make sure you know how to use this nose spray correctly.
            • Shake the spray gently and clear your nose before each use.
            • Before using it for the first time or if you haven't used it in 2 days, prime the spray pump until you see a fine mist.
            • Breathe in slowly as you're spraying and tilt your head back slightly after spraying. Wait 15 minutes before blowing your nose if needed.
            • Some people get minor nose irritation, nosebleeds, sore throat, or headaches after using it.
            • Starts working in a few hours. Only take it once a day.
            • Can make you feel sleepy, so take it at bedtime if needed.
            • Avoid some of the side effects by drinking plenty of non-caffeinated liquids.
            • If you need to use it for more than a few weeks, talk with your doctor about trying a nasal steroid instead since it might work better for you long-term.
            • Using an antihistamine eye drop instead can also work better to treat itchy or watery eyes.
            Learn more
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