Prescription onlyLower-cost generic available

Actigall

(Ursodiol)

Prescription onlyLower-cost generic available
  • Pill
  • Gallbladder stone
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Dissolves gallbladder stones.

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Our bottom line

Actigall (Ursodiol) is a decent way to get rid of gallstones if surgery isn't an option for you.

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Upsides

  • Helps dissolve gallbladder stones without needing to have surgery.

Downsides

  • Can take long time for gallstones to be fully dissolved.
  • May not work depending on the initial size of the gallstone.
  • Often causes upset stomach.
  • Can be pricey.
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Side effect rates for Actigall (Ursodiol)

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These are side effects of Actigall (Ursodiol) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Actigall (Ursodiol)

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  • Bile acid sequestering agents (like Cholestyramine and Colestipol) and aluminum-based antacids can interfere with how well Actigall (Ursodiol) works by not letting it be absorbed by your body. Estrogens, oral contraceptives, and clofibrate (and perhaps other lipid-lowering drugs) can cause gallstones to be made and work against the effectiveness of Actigall (Ursodiol).

Common concerns from people taking Actigall (Ursodiol)

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Pregnancy
Food
  • Take with food to lessen upset stomach.