Prescription onlyNo lower cost generic available

Vesicare Alternatives

(Solifenacin)

  • Pill
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Compare Vesicare (Solifenacin) to alternatives

These medications are comparable to Vesicare (Solifenacin) or used for similar purposes.

Vesicare
(Solifenacin)

Oxytrol
(Oxybutynin)

Oxytrol
(Oxybutynin)

Enablex
(Darifenacin)

Oxytrol
(Oxybutynin)

Detrol
(Tolterodine)

Sanctura
(Trospium)

Treats an overactive bladder. Vesicare (Solifenacin) is a good treatment for overactive bladder and doesn’t have as many side effects as similar medications.Treats an overactive bladder. Oxytrol (Oxybutynin) is a good treatment for overactive bladder, but watch out for side effects such as dry mouth and constipation.Treats an overactive bladder. Oxytrol (Oxybutynin) is a good treatment for overactive bladder, but watch out for side effects such as dry mouth and constipation.Coming soon.Treats an overactive bladder. Oxytrol (Oxybutynin) is a good treatment for overactive bladder, but watch out for side effects such as dry mouth and constipation.Coming soon.Coming soon.
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Reviews & ratings
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Side effects
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
  • Dry mouth 24%
  • Constipation 10%
  • Vision blurred 3%
  • Indigestion 3%
  • Urinary tract infection nos 2%
  • Fatigue 1%
  • Dry eyes nos 1%
  • Flu 1%
  • Abdominal pain upper 1%
  • Nausea 1%
More Vesicare side effects »

We haven’t found good data for Oxybutynin side effects.

FDA side effect reports for Oxybutynin »

We haven’t found good data for Oxybutynin side effects.

FDA side effect reports for Oxybutynin »
  • Dry mouth 27%
  • Constipation 13%
  • Indigestion 5%
  • Abdominal pain 3%
  • Urinary tract infection 2%
  • Nausea 2%
  • Muscle weakness 2%
  • Headache 1%
  • Dizziness 1%
  • Dry eyes 1%
More Enablex side effects »

We haven’t found good data for Oxybutynin side effects.

FDA side effect reports for Oxybutynin »

We haven’t found good data for Detrol side effects.

FDA side effect reports for Detrol »

We haven’t found good data for Sanctura side effects.

FDA side effect reports for Sanctura »
How it works
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
Vesicare (Solifenacin) is an anticholinergic. It relaxes the bladder muscles by lowering muscle spasms. This helps people go to the bathroom less often and better control their urination.Oxytrol (Oxybutynin) is an anticholinergic. It relaxes the bladder muscles by lowering muscle spasms. This helps people go to the bathroom less often and better control their urination.Oxytrol (Oxybutynin) is an anticholinergic. It relaxes the bladder muscles by lowering muscle spasms. This helps people go to the bathroom less often and better control their urination.Coming soon.Oxytrol (Oxybutynin) is an anticholinergic. It relaxes the bladder muscles by lowering muscle spasms. This helps people go to the bathroom less often and better control their urination.Coming soon.Coming soon.
Type of medication
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
Antispasmodic
Anticholinergic
Prescription only
Antispasmodic
Anticholinergic
Prescription only
Antispasmodic
Anticholinergic
Prescription only
Coming soon.
Antispasmodic
Anticholinergic
Prescription only
Coming soon.Prescription only
Coming soon.
Available as
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
  • Pill
  • Pill
  • Extended release
  • Liquid
  • Cream, gel, or ointment
  • Patch
  • Pill
  • Extended release
  • Liquid
  • Cream, gel, or ointment
  • Patch
  • Extended release
  • Pill
  • Extended release
  • Liquid
  • Cream, gel, or ointment
  • Patch
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
  • Bladder muscle dysfunction - overactive
  • Bladder muscle dysfunction - overactive
  • Bladder muscle dysfunction - overactive
Risk factors for serious side effects
VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Outside in hot weather
    • Dehydrated
    • Exercising
      • History of cardiovascular disease
      • Higher dose of Vesicare (Solifenacin) Taking with other medicines that prolong QT interval (heart problems)
      Detailed Vesicare (Solifenacin) risks & warnings »
      Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
      Pregnancy category
      VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      No specific alcohol-related info.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      • Can be taken with or without food.
      • Can be taken with or without food.
      • Can be taken with or without food.
      • Can be taken with or without food.
      No specific food-related info.
      • Can be taken with or without food.
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
      Sleep
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • Vesicare (Solifenacin) can cause drowsiness, confusion, dizziness, hallucinations, or blurred vision. Avoid driving, operating machinery, or doing anything that requires you to be alert until you know how Vesicare (Solifenacin) affects you.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      No specific sleep-related info.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
      • Can be taken with or without food.
      • Causes fewer side effects than other medications in the same drug class.
      • Only needs to be taken once a day.
      • Vesicare (Solifenacin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
      • Oxytrol (Oxybutynin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
      • Available in multiple forms: a patch, gel, extended-release tablet, and tablet.
      • The gel form of Oxytrol (Oxybutynin) is available over the counter without a prescription.
      • Oxytrol (Oxybutynin) patch and gel have fewer side effects than taking the tablet.
      • The tablet is available as a generic.
      • Oxytrol (Oxybutynin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
      • Available in multiple forms: a patch, gel, extended-release tablet, and tablet.
      • The gel form of Oxytrol (Oxybutynin) is available over the counter without a prescription.
      • Oxytrol (Oxybutynin) patch and gel have fewer side effects than taking the tablet.
      • The tablet is available as a generic.
      Coming soon.
      • Oxytrol (Oxybutynin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
      • Available in multiple forms: a patch, gel, extended-release tablet, and tablet.
      • The gel form of Oxytrol (Oxybutynin) is available over the counter without a prescription.
      • Oxytrol (Oxybutynin) patch and gel have fewer side effects than taking the tablet.
      • The tablet is available as a generic.
      Coming soon.Coming soon.
      Downsides and risks
      VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
      • Not recommended if you have ulcerative colitis or certain other gastrointestinal problems, since Vesicare (Solifenacin) can slow stomach emptying.
      • Has some drug interactions, so make sure your doctor has your complete list of medications.
      • Not available as a generic.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Can’t be used if you have uncontrolled narrow-angle glaucoma.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Can’t be used if you have uncontrolled narrow-angle glaucoma.
      • Not recommended if you have ulcerative colitis or certain other stomach problems since Oxytrol (Oxybutynin) can slow stomach emptying.
      • Not the best choice if you have GERD (acid reflux), since Oxytrol (Oxybutynin) can irritate your throat and make the acid reflux worse.
      • Has more side effects than newer medicines that treat overactive bladder.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Can’t be used if you have uncontrolled narrow-angle glaucoma.
      • Not recommended if you have ulcerative colitis or certain other stomach problems since Oxytrol (Oxybutynin) can slow stomach emptying.
      • Not the best choice if you have GERD (acid reflux), since Oxytrol (Oxybutynin) can irritate your throat and make the acid reflux worse.
      • Has more side effects than newer medicines that treat overactive bladder.
      Coming soon.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Can’t be used if you have uncontrolled narrow-angle glaucoma.
      • Not recommended if you have ulcerative colitis or certain other stomach problems since Oxytrol (Oxybutynin) can slow stomach emptying.
      • Not the best choice if you have GERD (acid reflux), since Oxytrol (Oxybutynin) can irritate your throat and make the acid reflux worse.
      • Has more side effects than newer medicines that treat overactive bladder.
      Coming soon.Coming soon.
      Tips from our pharmacists for people taking the medication
      VesicareOxybutyninOxybutyninEnablexOxybutyninDetrolSanctura
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can be taken with or without food.
      • Let your doctor know if your symptoms don’t get better in two weeks. There could be other causes of your bladder problems or you may need to try a different medicine.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can be taken with or without food.
      • Let your doctor know if your symptoms don’t get better in two weeks. There could be other causes of your bladder problems or you may need to try a different medicine.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can be taken with or without food.
      • Let your doctor know if your symptoms don’t get better in two weeks. There could be other causes of your bladder problems or you may need to try a different medicine.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      Coming soon.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can be taken with or without food.
      • Let your doctor know if your symptoms don’t get better in two weeks. There could be other causes of your bladder problems or you may need to try a different medicine.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      Coming soon.Coming soon.
      Learn more
      More about VesicareSide effectsReviews & ratingsAlternativesFDA package insert
      More about OxybutyninSide effectsReviews & ratingsFDA package insert
      More about OxybutyninSide effectsReviews & ratingsFDA package insert
      More about EnablexSide effectsReviews & ratingsFDA package insert
      More about OxybutyninSide effectsReviews & ratingsFDA package insert
      More about DetrolSide effectsFDA package insert
      More about SancturaSide effectsFDA package insert