Prescription onlyClass: Endocrine

Victoza Alternatives

(liraglutide)

Prescription onlyClass: Endocrine
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Compare Victoza (liraglutide) to alternatives

These medications are comparable to Victoza (liraglutide) or used for similar purposes.

Victoza
(liraglutide)

Farxiga
(dapagliflozin)

Invokana
(canagliflozin)

Glucotrol
(glipizide)

Jardiance
(empagliflozin)

Januvia
(sitagliptin)

Byetta
(exenatide)

Actos
(pioglitazone)

Byetta
(exenatide)

Trulicity
(dulaglutide)

Diabeta
(glyburide)

Tradjenta
(linagliptin)

Lowers your blood sugar. Victoza (liraglutide) is a medicine you inject once a day to control diabetes, but it can be expensive.Lowers blood sugar. Farxiga (dapagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.Lowers blood sugar. Invokana (canagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.Lowers blood sugar. Glucotrol (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low so you must always carry some form of sugar with you that can be readily used.Lowers blood sugar. Jardiance (empagliflozin) lowers blood sugar for people with diabetes, but can increase the chance of a yeast infection.Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.Lowers blood sugar. Byetta (Exenatide) can lower your blood sugars in addition to metformin. It does not increase your appetite unlike some other anti-diabetics, but must be given by injection and usually causes upset stomach.Lowers blood sugar. Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.Lowers blood sugar. Byetta (Exenatide) can lower your blood sugars in addition to metformin. It does not increase your appetite unlike some other anti-diabetics, but must be given by injection and usually causes upset stomach.Lowers your blood sugar. Trulicity (dulaglutide) is a once-weekly injectable medicine that's used to control diabetes, but it can be expensive.Lowers blood sugar. Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.Lowers blood sugar. Tradjenta (linagliptin) is good add-on medicine for controlling your blood sugar, but may cause body aches.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
6.5Victoza
Reviews for Victoza
73%
of people (All ages) say Victoza is worth it
91%
say it works well
27%
say it's a big hassle
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Farxiga (dapagliflozin)?
Worth itNot sureNot worth it
Reviews for Invokana
67%
+6% better vs. Victoza
56%
+35% better vs. Victoza
19%
-8% worse vs. Victoza
Have you used Invokana (canagliflozin)?
Worth itNot sureNot worth it
Reviews for Glucotrol
50%
+23% better vs. Victoza
32%
+59% better vs. Victoza
19%
-8% worse vs. Victoza
332 reviews
Have you used Glucotrol (glipizide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Jardiance (empagliflozin)?
Worth itNot sureNot worth it
Reviews for Januvia
44%
+29% better vs. Victoza
34%
+57% better vs. Victoza
17%
-10% worse vs. Victoza
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Byetta (exenatide)?
Worth itNot sureNot worth it
Reviews for Actos
42%
+31% better vs. Victoza
30%
+61% better vs. Victoza
21%
-6% worse vs. Victoza
175 reviews
Have you used Actos (pioglitazone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Byetta (exenatide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Trulicity (dulaglutide)?
Worth itNot sureNot worth it
Reviews for glyburide
45%
+28% better vs. Victoza
34%
+57% better vs. Victoza
21%
-6% worse vs. Victoza
110 reviews
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Tradjenta (linagliptin)?
Worth itNot sureNot worth it
Side effects
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Nausea 13%
  • Headache 4%
  • Diarrhea 6%
  • Low appetite 9%
  • Runny nose and congestion 1%
  • Head cold 1%
  • Vomiting 4%
  • Constipation 4%
  • Indigestion 3%
  • Back pain 1%
More Victoza side effects »
  • Female yeast infection 6%
  • Common cold symptoms 1%
  • Urinary tract infection 2%
  • Increased urination 1%
  • Male yeast infection 3%
  • Nausea 1%
  • Flu 1%
More Farxiga side effects »
  • Yeast infection in women 8%
  • Urinary tract infections 2%
  • Increased urination 4%
  • Yeast infection in men 3%
  • Thirst 3%
  • Vaginal itching 2%
  • Constipation 1%
  • Abdominal pain 1%
More Invokana side effects »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Low blood sugar 3%
  • Constipation 3%
  • Nausea 3%
  • Headache 2%
More Glucotrol side effects »
  • Low blood sugar 3%
  • Urinary tract infection 1%
  • Yeast infection in women 3%
  • Elevated cholesterol levels 1%
  • Increased urination 2%
  • Yeast infection in men 3%
  • Nausea 1%
More Jardiance side effects »
  • Common cold 2%
  • Diarrhea 1%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »
  • Low blood sugar 11%
  • Nausea 33%
  • Diarrhea 10%
  • Vomiting 14%
  • Headache 10%
  • Constipation 8%
  • Indigestion 5%
  • Weakness 4%
  • Abdominal swelling 3%
  • Loss of appetite 3%
More Byetta side effects »
  • Swelling 11%
  • Low blood sugar 8%
  • Colds and flu 4%
  • Headache 2%
  • Heart failure 2%
  • Sinus infection 1%
  • Back pain 1%
  • Muscle pain 2%
More Actos side effects »
  • Low blood sugar 11%
  • Nausea 33%
  • Diarrhea 10%
  • Vomiting 14%
  • Headache 10%
  • Constipation 8%
  • Indigestion 5%
  • Weakness 4%
  • Abdominal swelling 3%
  • Loss of appetite 3%
More Byetta side effects »
  • Nausea 7%
  • Diarrhea 2%
  • Stomach pain 2%
  • Vomiting 4%
  • Low appetite 3%
  • Low blood sugar 4%
  • Tiredness 1%
  • Constipation 3%
  • Indigestion 2%
More Trulicity side effects »
  • Nausea and heartburn 2%
  • Skin allergies 2%
More glyburide side effects »
  • Common cold 1%
  • Cough 1%
  • Urinary tract infection 3%
  • High blood fat (triglyceride) 2%
  • High cholesterol 2%
  • Weight gain 1%
  • Constipation 1%
  • Back pain 9%
  • Joint pain 8%
More Tradjenta side effects »
How it works
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
Victoza (liraglutide) is a medication for diabetes. It stimulates your body to make and release more insulin, stops the body from releasing more sugar, and slows down digestion.Farxiga (dapagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.Invokana (canagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.Glucotrol (glipizide) stimulates your body to release insulin and lower blood sugar.Jardiance (empagliflozin) is an anti-diabetes medication. It passes the sugar from your blood through your urine.Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.Byetta (Exenatide) enhances the release of insulin in your gut and pancreas to lower your blood sugar.Actos (pioglitazone) is a thiazolidinedione that improves your body's ability to use insulin to lower your blood sugar.Byetta (Exenatide) enhances the release of insulin in your gut and pancreas to lower your blood sugar.Trulicity (dulaglutide) is a medication for diabetes. It stimulates your body to make and release more insulin, stops the body from releasing more sugar, and slows down digestion.Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.Tradjenta (linagliptin) is an anti-diabetic medicine. It increases insulin and decreases glucagon production.
Type of medication
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Injection
  • Pill
  • Pill
  • Pill
  • Extended release pill
  • Pill
  • Pill
  • Injection
  • Pill
  • Injection
  • Injection
  • Pill
  • Pill
Used for
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
Risk factors for serious side effects
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • History of MTC
  • History of MEN 2
  • History of pancreatitis
  • History of gallstones
  • alcoholism
Detailed Victoza (liraglutide) risks & warnings »
  • Taking water pills for blood pressure
  • Over age 65
  • Kidney problems
  • Kidney damage
  • Taking water pills, ACE inhibitors or ARBs for blood pressure
Detailed Farxiga (dapagliflozin) risks & warnings »
  • History of amputations 
  • Peripheral vascular disease (narrowed blood vessels)
  • Nerve problems
  • Diabetic foot ulcers 
  • History of kidney damage
Detailed Invokana (canagliflozin) risks & warnings »
  • Skipping meals or having inconsistent meal times
  • Drinking alcohol
  • Using other blood sugar-lowering medicine
  • People age 60 or older
  • Those with kidney and/or liver problems
Detailed Glucotrol (glipizide) risks & warnings »
  • Over age 65
  • Kidney disease
  • Taking blood pressure medications
  • Dehydration
  • Poor baseline kidney function
Detailed Jardiance (empagliflozin) risks & warnings »
  • History of pancreatitis
  • High blood triglyceride levels
  • Gallstones (stones in gallbladder)
  • History of alchoholism
  • Kidney problems
Detailed Januvia (sitagliptin) risks & warnings »
  • Severe renal impairment
  • End-stage renal disease
  • Severe gastrointestinal disease
  • Gastroparesis
Detailed Byetta (exenatide) risks & warnings »
  • Heart failure
  • Current liver problems
  • History of bladder cancer
  • Women
Detailed Actos (pioglitazone) risks & warnings »
  • Severe renal impairment
  • End-stage renal disease
  • Severe gastrointestinal disease
  • Gastroparesis
Detailed Byetta (exenatide) risks & warnings »
  • History of MTC
  • History of MEN 2
  • History of pancreatitis
  • History of gallstones
  • alcoholism
Detailed Trulicity (dulaglutide) risks & warnings »
  • Over age 65
  • Kidney problems
  • Use of other blood sugar lowering medicines
  • Alcohol
  • Intense physical activity
Detailed Diabeta (glyburide) risks & warnings »
  • Alcoholism
  • Elevated triglycerides
  • History of pancreatitis
  • Exercising more than you usually do
Detailed Tradjenta (linagliptin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
No alcohol related info.
  • Not a good choice if you drink a lot of alcohol.
  • Avoid if you are a heavy drinker of alcohol.
  • Avoid drinking alcohol while taking Glucotrol (glipizide).
No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
No alcohol related info.
Food
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
No food related info.
  • Take once in the morning with or without food.
  • Take once daily before your first meal of the day.
  • You only have to take Invokana (canagliflozin) once a day before meals.
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
  • Take once a day in the morning with or without food.
  • Take once a day in the morning with or without food.
No food related info.
  • Take once a day with or without food.
No food related info.No food related info.
  • Eat well-balanced meals to avoid low blood sugar.
  • Take with or without meals.
Kidneys and liver
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Victoza (liraglutide) can cause or worsen kidney damage. This is more likely to happen if you've had nausea or vomiting, diarrhea or dehydration. Make sure to drink plenty of fluids and stay hydrated when you're sick. If you have kidney damage already, your doctor might do regular lab tests while you're taking Victoza (liraglutide) to make sure your kidneys stay healthy.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Farxiga (dapagliflozin) can cause or worsen kidney problems. If you already have severe kidney damage, you can't take Farxiga (dapagliflozin). You're more likely to have this happen if you're on certain medicines to lower your blood pressure or anti-inflammatory medicines (NSAIDs), have heart failure or mild kidney damage. Your doctor will have you do regular blood tests to make sure your kidneys are healthy.
  • Not for people with severe kidney problems.
No kidneys and liver related info.
  • Jardiance (empagliflozin) can cause or worsen kidney problems. Make sure to stay properly hydrated. Get blood test for kidney function before starting Jardiance (empagliflozin), a few weeks after starting, and regularly thereafter.
  • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
  • If you have severe kidney or liver problems, you should not take Byetta (Exenatide). Talk to your doctor about testing your kidneys before starting Byetta (Exenatide). People taking medications that are damaging to kidneys such as ACE inhibitors, NSAIDs or diuretics in addition to Byetta (Exenatide) may notice nausea, vomiting, or diarrhea.
  • If you've had liver problems or damage in the past, talk to your doctor before starting Actos (pioglitazone), since there's a small chance that it can hurt your liver. Tell your doctor about any stomach pain that don't go away, dark urine, or yellowing of eyes/skin. Your doctor will check your liver regularly.
  • If you have severe kidney or liver problems, you should not take Byetta (Exenatide). Talk to your doctor about testing your kidneys before starting Byetta (Exenatide). People taking medications that are damaging to kidneys such as ACE inhibitors, NSAIDs or diuretics in addition to Byetta (Exenatide) may notice nausea, vomiting, or diarrhea.
  • Trulicity (dulaglutide) can cause or worsen kidney damage. This is more likely to happen if you've had nausea or vomiting, diarrhea or dehydration. Make sure to drink plenty of fluids and stay hydrated when you're sick. If you have kidney damage already, your doctor might do regular lab tests while you're taking Trulicity (dulaglutide) to make sure your kidneys stay healthy.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Not ideal for elderly or those with poor kidney function.
  • Good option if you have bad liver or kidney function.
Pain
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
No pain related info.
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
  • Rarely, Invokana (canagliflozin) can hurt the kidneys. This is more likely to happen if you already have kidney damage, heart failure, or take certain medicines for blood pressure or anti-inflammatories (NSAIDs). Invokana (canagliflozin) can also lower your blood pressure since it makes you urinate more. Your doctor will check your kidneys by blood tests regularly, and might ask you to change how you take Invokana (canagliflozin). Make sure to stay hydrated to prevent low blood pressure and kidney problems.
No pain related info.
  • Let your doctor know of any constant dizziness, joint pain, cold-like symptoms, or unexplained nausea/vomiting.
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
  • Using Byetta (Exenatide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medicine for diabetes. You should not use Byetta (Exenatide) if you have gastroparesis, a condition that causes slow or irregular digestion. Gastroparesis can be common for people that have had uncontrolled diabetes for a while.
No pain related info.
  • Using Byetta (Exenatide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medicine for diabetes. You should not use Byetta (Exenatide) if you have gastroparesis, a condition that causes slow or irregular digestion. Gastroparesis can be common for people that have had uncontrolled diabetes for a while.
No pain related info.No pain related info.No pain related info.
Weight
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Helps with weight loss and controls appetite.
  • Can help you lose weight.
No weight related info.
  • Can cause mild weight gain of 2-3lb.
  • Can cause weight loss.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
No weight related info.
  • Can cause weight gain, headache, and swelling from fluid build-up.
  • Can cause weight gain.
No weight related info.
  • May help with weight loss and controling appetite.
  • Can cause weight gain, dizziness, or stomach upset.
  • Can cause weight gain (about 2 to 3 pounds).
  • Does not cause weight gain.
Upsides and benefits
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • Helps with weight loss and controls appetite.
  • Only medicine in this class with proven heart health benefits.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Medicine is ready to use, without need to mix.
  • Can lower A1c by 1% (A1c measures your average blood sugar over time.)
  • Can help you lose weight.
  • Less chance of low blood sugar than other diabetes medicines.
  • Lowers A1C (blood sugar) levels by 1%.
  • You only have to take Invokana (canagliflozin) once a day before meals.
  • Less likely to cause low blood sugar than other diabetes medicines.
  • Also available as a combination drug with metformin (Invokamet).
  • Lowers A1c levels by 1-2%.
  • Glucotrol (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
  • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
  • Okay to use by people with kidney problems.
  • Available as a generic form and is relatively cheap.
  • Lowers A1c (average blood sugar over time) levels up to 1%.
  • Can prevent death from heart attack, stroke, or heart failure if you have pre-existing heart disease.
  • Can be easily taken orally as a pill.
  • Can cause weight loss.
  • Not likely to cause hypoglycemia or very low blood sugar.
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
  • Can lower your A1c (average blood sugar over time) by 1%.
  • Not as likely to cause very low blood sugar as glyburine or insulin.
  • Does not increase your appetite like other anti-diabetic medicines.
  • Pen is dialed to a single dose for easy injections.
  • Improves sugar control and lowers A1c levels by around 1%.
  • Easily taken by mouth as a once a day pill.
  • Prevents the harmful effects of high sugar levels on your organs.
  • Rarely causes low blood sugar.
  • Lower the risk of heart attack or stroke.
  • Can lower your A1c (average blood sugar over time) by 1%.
  • Not as likely to cause very low blood sugar as glyburine or insulin.
  • Does not increase your appetite like other anti-diabetic medicines.
  • Pen is dialed to a single dose for easy injections.
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • May help with weight loss and controling appetite.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Dosed once a week compared to other injectables that have to be done daily.
  • Medicine is ready to use, without need to mix.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
  • Good add-on medicine if your blood sugars are still not controlled
  • Good option if you have bad liver or kidney function.
  • Can be taken once daily.
  • Does not cause weight gain.
  • Does not cause hypoglycemia (low blood sugar) when taken by itself.
Downsides and risks
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Compared to other similar medicines, you have to inject this every day.
  • Not a first choice medicine for diabetes because it doesn't lower blood sugar as much as other medicines.
  • Higher risk of genital yeast infections and urinary tract infections.
  • This is an expensive medication with no generic available at this time.
  • Not shown to improve cardiovascular outcomes like other similar medicines because it can increase cholesterol.
  • Not a good choice if you drink a lot of alcohol.
  • You're more likely to have broken bones, yeast infections and urinary tract infections with Invokana (canagliflozin).
  • There's a rare but serious risk of leg and foot amputations with Invokana (canagliflozin). Talk to your doctor if you develop new pain or infections in your feet.
  • Not for people with severe kidney problems.
  • Can raise your cholesterol.
  • Avoid if you are a heavy drinker of alcohol.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • While taking Glucotrol (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
  • Can cause mild weight gain of 2-3lb.
  • Might lose its effectiveness over time.
  • Needs to be taken 30 minutes before a meal for it to be most effective.
  • More expensive since it's available as brand name only.
  • Can cause dehydration.
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
  • Byetta (Exenatide) must be injected twice a day. Other medicines like it can be injected once daily or even weekly.
  • It commonly causes nausea, vomiting, diarrhea, constipation, or indigestion.
  • Can affect how well your antibiotics and birth control pills work. Take them no sooner than one hour after your injections.
  • May take several weeks to lower blood sugar.
  • Can cause weight gain.
  • People with heart failure or history of bladder cancer shouldn't use this medicine.
  • Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
  • Raises the risk of bone fractures, especially for people who already have a risk for fractures.
  • Byetta (Exenatide) must be injected twice a day. Other medicines like it can be injected once daily or even weekly.
  • It commonly causes nausea, vomiting, diarrhea, constipation, or indigestion.
  • Can affect how well your antibiotics and birth control pills work. Take them no sooner than one hour after your injections.
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Many people taking Trulicity (dulaglutide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
  • Not first-choice anti-diabetes medicine because it doesn't lower blood sugar levels as much as others.
  • Available as brand only and may be expensive
Tips from our pharmacists for people taking the medication
VictozaFarxigaInvokanaGlucotrolJardianceJanuviaByettaActosByettaTrulicityglyburideTradjenta
  • Inject the dose given by your doctor daily at the same time on your belly, thighs, or the back of your upper arm. To be used with or without food.
  • You may have low appetite, nausea, vomiting, diarrhea, or stomach pain, which may get better with time.
  • Let your doctor know if you have severe and/or persistent stomach pain or nausea with or without vomiting.
  • Unused pens should be stored in the refrigerator, but the pen in use can be kept at room temperature for up to 30 days.
  • Take once in the morning with or without food.
  • Farxiga (dapagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Do not take if you have kidney problems or bladder cancer.
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
  • Take once daily before your first meal of the day.
  • Invokana (canagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Can cause low blood sugar, so make sure to check your blood sugar if you don't feel well.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Invokana (canagliflozin).
  • Take the medicine 30 minutes before eating, usually before your first big meal of the day.
  • Avoid drinking alcohol while taking Glucotrol (glipizide).
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
  • Check your blood sugar regularly.
  • Glucotrol (glipizide) can cause dizziness so avoid activities that require coordination until you know how your body can handle the medicine.
  • Take once a day in the morning with or without food.
  • You urinate more often so make sure to stay properly hydrated.
  • Can lower blood pressure.
  • Increases the chances of yeast or urinary tract infection, so practice good hygiene.
  • Check blood sugar and blood pressure regularly.
  • Let your doctor know of any constant dizziness, joint pain, cold-like symptoms, or unexplained nausea/vomiting.
  • Take once a day in the morning with or without food.
  • Can cause headache and cold-like symptoms.
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
  • Tell your doctor right away if you are experiencing severe joint pain.
  • Check your blood sugar regularly to check for low blood sugar.
  • Inject into your belly, thighs, or upper arms within an hour of your main meals.
  • Store unused pens in the refrigerator.
  • After first use, pens can be kept at room temperature for 30 days.
  • Change the needle and prime the pen every time you inject.
  • If you're also on insulin, don't inject into the same site.
  • Best to check your blood sugar once a day to make sure your medicine is working properly.
  • Take once a day with or without food.
  • May need several weeks to see full effect on blood sugar control.
  • Can cause weight gain, headache, and swelling from fluid build-up.
  • Tell your doctor about any shortness of breath, heart troubles, or unusual swelling.
  • Not recommended for patients with a history of heart failure or bladder cancer.
  • Check your blood sugar regularly.
  • Inject into your belly, thighs, or upper arms within an hour of your main meals.
  • Store unused pens in the refrigerator.
  • After first use, pens can be kept at room temperature for 30 days.
  • Change the needle and prime the pen every time you inject.
  • If you're also on insulin, don't inject into the same site.
  • Best to check your blood sugar once a day to make sure your medicine is working properly.
  • Each pen has only 1 dose and it's ready for use.
  • Inject once a week in your belly, thighs, or the back of your upper arm with or without food.
  • If you miss a dose, take the medicine as soon as you remember, unless the next dose is within the next 72 hours, then skip the missed dose.
  • You may have low appetite, nausea, vomiting, diarrhea, or stomach pain, which may get better with time.
  • Let your doctor know if you have severe and/or persistent stomach pain or nausea with or without vomiting.
  • Unopened pens should be kept in the refrigerator, or at room temperature for up to 14 days, but never in the freezer.
  • Check your blood sugar regularly.
  • Eat well-balanced meals to avoid low blood sugar.
  • Works best if you take it 30 minutes before first main meal of the day.
  • Can cause weight gain, dizziness, or stomach upset.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
  • Take with or without meals.
  • Maintain a consistent diet and exercise schedule to prevent changes in your blood sugar.
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