Prescription onlyLower-cost generic availableClass: Infection


(didanosine or ddl)

Prescription onlyLower-cost generic availableClass: Infection
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Works with other medicines to treat HIV infection.

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Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, Videx can be a difficult drug to take. Videx has numerous serious side effects. It is also difficult taking Videx twice a day on an empty stomach.

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  • The oral solution can be stored in the refrigerator for up to 30 days.
  • While Videx doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.


  • Must take on an empty stomach at least 30 minutes before, or 2 hours after eating.
  • Take twice a day.
  • The amount of Videx you will take is based on your body weight, kidney, and liver function.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
How it works

Videx stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.

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Side effect rates for Videx (didanosine or ddl)

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These are side effects of Videx (didanosine or ddl) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Videx (didanosine or ddl)

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    • Higher risk if:
    • Kidney problems
    • Use of stavudine, another HIV drug

    Serious, even deadly, pancreatitis (infections of the pancreas) has occurred during treatment with Videx when used alone or in combination with other HIV medications. Videx should be stopped immediately in people with signs or symptoms of pancreatitis.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Videx (didanosine or ddl)

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Kidneys and liver
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Videx can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use Videx. It may not be a good choice for people with liver problems.