Prescription onlyNo lower cost generic available



Prescription onlyNo lower cost generic available
  • Pill
Back to: Full Site NavigationSkip to: side effects sectionSkip to: What to expect sectionSkip to: Risks and warnings sectionSkip to: Common concerns from users and pharmacists

Treats depression.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Viibryd (Vilazodone) is a good option to treat depression, but it often causes stomach and intestinal problems, including diarrhea.

Coupons and discounts


  • Viibryd (Vilazodone) improves depressive symptoms in people with major depressive disorder.
  • The dose of Viibryd (Vilazodone) doesn’t need to be changed if you have severe kidney disease.
  • Compared to other antidepressants, it has a lower risk of weight gain and causing problems with sexual function.
People say this drug is:
95 reviews


  • You shouldn’t take Viibryd (Vilazodone) if you have severe liver problems.
  • Can’t take Viibryd (Vilazodone) with drugs called monoamine oxidase inhibitors (MAOIs).
  • Need to avoid drinking alcohol while taking Viibryd (Vilazodone).
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Viibryd (Vilazodone)

869 From clinical trials of Viibryd / Depression (40 mg)
  • Diarrhea
  • Nausea
  • Dizziness
  • Dry mouth
  • Sleep difficulty
  • Decreased libido
  • Vomiting
  • Lower sex drive
  • Fatigue
  • Abnormal orgasm

Risks and Warnings for Viibryd (Vilazodone)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Age 18 years or younger

    Viibryd (Vilazodone) can increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment, or when the dose changes. Report anything concerning to a doctor immediately. Viibryd (Vilazodone) is not approved for children younger than age 18 years.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Viibryd (Vilazodone)

Final section. Do you want to return to drug navigation?
  • I drink kefir every morning to counteract the diarrhea. Other than the diarrhea I have had excess sweating when I work out
  • Need to avoid drinking alcohol while taking Viibryd (Vilazodone).
  • Take Viibryd (Vilazodone) with food at the same time every day.
  • Take with food! Helps with the awful stomach side effects, & is imperative for the drug to work. Taking without food decreases efficiency. Viibryd, gave me constant "brain zaps" even when taken consistently, and worse when starting/ending.
  • Helps to take with food and plenty of water. Mornings have personally worked best.
  • Do take with food. I didn't experience GI issues, but it felt almost like I skipped the dose if I took it without food. Had a lot of trouble sleeping at first and with dose change - melatonin helped get through those periods
Kidneys and liver
  • The dose of Viibryd (Vilazodone) doesn’t need to be changed if you have severe kidney disease.
  • Higher doses led to anorgasmia (inability to ejaculate). Lowering the dose and supplementing with Ritalin has allowed successful treatment and ended the side-effects.
  • All medicine has side effects. Have to weigh the inconvenience of side effects over the inconvenience of being depressed