Prescription onlyLower-cost generic available

Vivelle-Dot

(Estradiol Patch)

Prescription onlyLower-cost generic available
  • Patch
  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
  • Low estrogen
  • Primary ovarian failure
  • Prevention of postmenopausal osteoporosis
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Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

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Our bottom line

The Vivelle-Dot (Estradiol Patch) needs to be replaced twice a week, but it comes in more strengths than other patches. It may have fewer side effects than oral estrogen pills.

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Upsides

  • Comes in 4 different strengths.
  • The Vivelle-Dot (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
  • Improves mood, energy, and mental alertness for some people.

Downsides

  • You need to replace the Vivelle-Dot (Estradiol Patch) twice a week, compared to other patches that are once a week.
  • Patch can fall off.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Vivelle-Dot (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
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Side effect rates for Vivelle-Dot (Estradiol Patch)

289 From clinical trials of Vivelle-Dot / Estrogen replacement (0.1 mg/day)
  • Headache
  • Breast tenderness
  • Vaginal bleeding between periods
  • Back pain
  • Flu
  • Common cold
  • Neck pain
  • Ear, nose, or throat infection
  • Sinus congestion
  • Pain

Risks and Warnings for Vivelle-Dot (Estradiol Patch)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Vivelle-Dot (Estradiol Patch)

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Pregnancy
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  • Can cause nausea, dizziness, bloating, and breast tenderness.