Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.
Our pharmacists’ bottom line
The Vivelle-Dot (Estradiol Patch) needs to be replaced twice a week, but it comes in more strengths than other patches. It may have fewer side effects than oral estrogen pills.
- Comes in 4 different strengths.
- The Vivelle-Dot (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
- The patch is good for people who don't want to take daily pills.
- Can be worn while swimming, bathing, and showering.
- By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
- Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
- Improves mood, energy, and mental alertness for some people.
- You need to replace the Vivelle-Dot (Estradiol Patch) twice a week, compared to other patches that are once a week.
- Patch can fall off.
- Increases your risk of uterine and breast cancer.
- If you have your uterus, you have to use the Vivelle-Dot (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
- Increases your risk of developing blood clots and stroke.
- Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
- Can't be used in people with liver problems.
Side effects for Vivelle-Dot (Estradiol Patch)
From clinical trials of Vivelle-Dot / Estrogen replacement (0.1 mg/day) ( 289)
- HeadacheHeadache26% for Vivelle-Dot patch vs.24% for placebo
- Breast tendernessBreast tenderness13% for Vivelle-Dot patch vs.0% for placebo
- Vaginal bleeding between periodsVaginal bleeding between periods11% for Vivelle-Dot patch vs.5% for placebo
- Back painBack pain11% for Vivelle-Dot patch vs.6% for placebo
- FluFlu8% for Vivelle-Dot patch vs.9% for placebo
- Common coldCommon cold8% for Vivelle-Dot patch vs.15% for placebo
- Neck painNeck pain5% for Vivelle-Dot patch vs.1% for placebo
- Ear, nose, or throat infectionEar, nose, or throat infection5% for Vivelle-Dot patch vs.6% for placebo
- Sinus congestionSinus congestion5% for Vivelle-Dot patch vs.5% for placebo
- PainPain5% for Vivelle-Dot patch vs.5% for placebo
Manufacturers don’t say how common these side effects are
- High blood pressure
- Hot flashes
- Weight increased
What to expect when you start Vivelle-Dot (Estradiol Patch)Skip what to expect section. Skip to Risks & Warnings section.
- Remove the patch by tearing the package by hand and not with scissors. Never cut the patch.
- Apply the sticky side of the patch to clean, dry, hairless skin below your waistline on areas as instructed by the manufacturer (never on your breast).
- Replace the patch twice a week (every 3-4 days) on a different area of your skin to lower your risk of skin irritation.
- Fold together the sticky sides of used patches before throwing them away to avoid exposing others to the medicine. Don't flush them down the toilet.
- Shouldn't be used forever. Talk to your doctor regularly to see if you still need treatment.
- Can cause nausea, dizziness, bloating, and breast tenderness.
- Tell your doctor about any unusual vaginal bleeding.
- Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
Risks and Warnings for Vivelle-Dot (Estradiol Patch)Skip Risks and Warnings section. Skip to Tips section.
- Higher risk if:
- › Using estrogen for more than one year
Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.