Prescription onlyClass: Cardiovascular

Vytorin 

(ezetimibe / simvastatin)

Prescription onlyClass: Cardiovascular
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Lowers cholesterol.

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Our bottom line

Vytorin is expensive and is no more effective than simvastatin by itself.

Price and discounts
Prices and coupons for 30 (10mg/40mg) tablets of ezetimibe / simvastatin

Upsides

  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
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Downsides

  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
How it works

Vytorin is a combination cholesterol-lowering medicine. Simvastatin prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). Ezetimibe prevents cholesterol absorption in your intestines.

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Side effect rates for Vytorin (ezetimibe / simvastatin)

  • Headache
  • Any side effect
  • Muscle pain
  • Ear, nose, or throat infection
  • Increased alt
  • Ear, nose, or throat infection
  • Muscle pain
  • Diarrhea
  • Flu
  • Pain in extremity

Risks and Warnings for Vytorin (ezetimibe / simvastatin)

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    • Higher risk if:
    • Asian patients taking high-dose niacin

    People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.

Common concerns from people taking Vytorin (ezetimibe / simvastatin)

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Pregnancy
Kidneys and liver
  • People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.
Sleep
  • Take medication at sleep time after 6 months cholesterol and triglycerides did improve