Prescription onlyLower-cost generic available

Xanax Alternatives

(Alprazolam)

Prescription onlyLower-cost generic available
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
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Compare Xanax (Alprazolam) to alternatives

These medications are comparable to Xanax (Alprazolam) or used for similar purposes.

Xanax
(Alprazolam)

Klonopin
(Clonazepam)

Valium
(Diazepam)

Ativan
(Lorazepam)

Helps you relax. Xanax (Alprazolam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and longer-term for panic attacks. More likely to cause withdrawal symptoms compared to similar drugs.Controls seizures and helps you relax. Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.Helps you relax. Valium (Diazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and for pain and sleeplessness from muscle spasm. Less severe withdrawal symptoms compared to similar drugs.Helps you relax. Ativan (Lorazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and sleep. Less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.
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Reviews & ratings
Filter group. All currently selected
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5.335719968178202Xanax
Reviews for Xanax (Alprazolam)
74%
of people (All ages) say Xanax (Alprazolam) is worth it
55%
say it works well
13%
say it's a big hassle
1257 reviews
Have you used Xanax (Alprazolam)?
Worth itNot sureNot worth it
Reviews for Klonopin (Clonazepam)
69%
5% vs. Xanax (Alprazolam)
51%
4% vs. Xanax (Alprazolam)
15%
2% vs. Xanax (Alprazolam)
703 reviews
Have you used Klonopin (Clonazepam)?
Worth itNot sureNot worth it
Reviews for Valium (Diazepam)
69%
5% vs. Xanax (Alprazolam)
52%
3% vs. Xanax (Alprazolam)
16%
3% vs. Xanax (Alprazolam)
944 reviews
Have you used Valium (Diazepam)?
Worth itNot sureNot worth it
Reviews for Ativan (Lorazepam)
70%
4% vs. Xanax (Alprazolam)
50%
5% vs. Xanax (Alprazolam)
15%
2% vs. Xanax (Alprazolam)
618 reviews
Have you used Ativan (Lorazepam)?
Worth itNot sureNot worth it
Side effects
XanaxKlonopinValiumAtivan
  • Drowsiness 34%
  • Impaired coordination 22%
  • Slurred speech 17%
  • Memory impairment 11%
  • Constipation 11%
  • Increased appetite 10%
  • Weight gain 9%
  • Cognitive disorder 8%
  • Decreased libido 6%
  • Fatigue and tiredness 6%
More Xanax side effects »
  • Dizziness 8%
  • Low mood disorder 7%
  • Ear, nose, or throat infection 6%
  • Sinus inflammation 5%
  • Fatigue 5%
  • Menstrual cramps 4%
  • Memory disturbance 3%
  • Constipation 3%
  • Allergic reaction 3%
  • Vaginal inflammation 3%
More Klonopin side effects »

The Valium FDA package insert doesn’t have numbers about how common side effects are.

More about Valium side effects »

The Ativan FDA package insert doesn’t have numbers about how common side effects are.

More about Ativan side effects »
How it works
XanaxKlonopinValiumAtivan
Xanax (Alprazolam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Klonopin (Clonazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.Valium (Diazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.Ativan (Lorazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.
Type of medication
XanaxKlonopinValiumAtivan
Anti-anxiety
Benzodiazepine
Prescription only
Anti-anxiety
Benzodiazepine
Prescription only
Anti-anxiety
Benzodiazepine
Prescription only
Anti-anxiety
Benzodiazepine
Prescription only
Available as
XanaxKlonopinValiumAtivan
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
  • Pill
  • Dissolving tablet
  • Pill
  • Liquid
  • Rectal gel
  • Pill
  • Liquid
Used for (click to learn more)
XanaxKlonopinValiumAtivan
Risk factors for serious side effects
XanaxKlonopinValiumAtivan
  • History of drug abuse
  • Taking with alcohol or drugs
  • Taking more than 4 mg/day or longer than 12 weeks
  • Stopping Xanax (Alprazolam) suddenly
  • Severely depressed
  • Taking with alcohol or drugs
  • First trimester of pregnancy
  • Current liver problems
Detailed Xanax (Alprazolam) risks & warnings »
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
    • Alcohol
    • Taking other medicines that make you less alert
      Detailed Klonopin (Clonazepam) risks & warnings »
      • Taking more than the prescribed dose
      • Taking longer than 4 weeks
      • History of drug abuse
      • Long-term use
        • Alcohol
        • Taking other medicines that make you less alert
          • Current liver problems
          Detailed Valium (Diazepam) risks & warnings »
          • Taking more than the prescribed dose
          • Taking longer than 4 weeks
          • History of drug abuse
          • Long-term use
            • Alcohol
            • Taking other medicines that make you less alert
              Detailed Ativan (Lorazepam) risks & warnings »
              Pregnancy

              Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              Interactions
              XanaxKlonopinValiumAtivan
              No interactions related info.No interactions related info.No interactions related info.
              • Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.
              Alcohol
              XanaxKlonopinValiumAtivan
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Not safe to use with alcohol.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Not safe to use with alcohol.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Not safe to use with alcohol.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Not safe to use with alcohol.
              Kidneys and liver
              XanaxKlonopinValiumAtivan
              • Processed by the liver, so might not be the best choice if you have liver problems.
              No kidneys and liver related info.
              • Processed by the liver, so might not be the best choice if you have liver problems.
              No kidneys and liver related info.
              Sleep
              XanaxKlonopinValiumAtivan
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can cause temporary dizziness and drowsiness.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can cause dizziness, drowsiness, and salivation.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can cause temporary dizziness and drowsiness.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can cause temporary dizziness and drowsiness.
              Upsides and benefits
              XanaxKlonopinValiumAtivan
              • Effective longer-term for panic attacks.
              • Effective at relieving short-term anxiety.
              • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
              • Can be used alone or with other medicines to treat seizures.
              • Effective at relieving short-term anxiety and sleeplessness.
              • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
              • Less severe withdrawal symptoms compared to other benzodiazepines.
              • Effective at relieving muscle spasms caused by a variety of conditions.
              • Effective at relieving short-term anxiety and sleeplessness.
              • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
              • Less severe withdrawal symptoms compared to other benzodiazepines.
              • Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.
              • Effective at relieving short-term anxiety and sleeplessness.
              • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
              Downsides and risks
              XanaxKlonopinValiumAtivan
              • Processed by the liver, so might not be the best choice if you have liver problems.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Most people find that it gets less effective over time.
              • Processed by the liver, so might not be the best choice if you have liver problems.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Most people find that it gets less effective over time.
              • Can cause memory problems, drowsiness, dizziness, and confusion.
              • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
              • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
              • Most people find that it gets less effective over time.
              Tips from our pharmacists for people taking the medication
              XanaxKlonopinValiumAtivan
              • Good for short-term relief of anxiety symptoms.
              • Starts working in 45 minutes when swallowed.
              • Can cause temporary dizziness and drowsiness.
              • Addictive. Long-term use can cause dependence or abuse.
              • Not safe to use with alcohol.
              • For the first week, avoid activities that require you to be alert.
              • Can cause dizziness, drowsiness, and salivation.
              • Report any confusion or inability to control muscle movements to your doctor.
              • Not safe to use with alcohol.
              • Helpful with muscle spasms.
              • Good for short-term relief of anxiety symptoms.
              • Starts working in 30 minutes when swallowed.
              • Can cause temporary dizziness and drowsiness.
              • Addictive. Long-term use can cause dependence or abuse.
              • Not safe to use with alcohol.
              • Starts working in 10 to 20 minutes when dissolved under your tongue.
              • Good for short-term relief of anxiety symptoms.
              • Starts working in 45 minutes when swallowed.
              • Can cause temporary dizziness and drowsiness.
              • Addictive. Long-term use can cause dependence or abuse.
              • Not safe to use with alcohol.
              Learn more
              More about XanaxSide effectsReviews & ratingsAlternativesFDA package insert
              Have you used Xanax (Alprazolam)?
              Worth itNot sureNot worth it
              More about KlonopinSide effectsReviews & ratingsFDA package insert
              Have you used Klonopin (Clonazepam)?
              Worth itNot sureNot worth it
              More about ValiumSide effectsReviews & ratingsFDA package insert
              Have you used Valium (Diazepam)?
              Worth itNot sureNot worth it
              More about AtivanSide effectsReviews & ratingsFDA package insert
              Have you used Ativan (Lorazepam)?
              Worth itNot sureNot worth it