Prescription onlyLower-cost generic availableClass: Mental health

Xanax Alternatives

(alprazolam)

Prescription onlyLower-cost generic availableClass: Mental health
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Compare Xanax (alprazolam) to alternatives

These medications are comparable to Xanax (alprazolam) or used for similar purposes.

Xanax
(alprazolam)

Klonopin
(clonazepam)

Valium
(diazepam)

Ativan
(lorazepam)

Helps you relax. Xanax (Alprazolam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and longer-term for panic attacks. More likely to cause withdrawal symptoms compared to similar drugs.Controls seizures and helps you relax. Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.Helps you relax. Valium (Diazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and for pain and sleeplessness from muscle spasm. Less severe withdrawal symptoms compared to similar drugs.Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.
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Coupons for Xanax
Best available price for 60 (0.5mg) tablets of xanax
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.35Xanax
Reviews for Xanax
74%
of people (All ages) say Xanax is worth it
55%
say it works well
13%
say it's a big hassle
1287 reviews
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it
Reviews for Klonopin
70%
+4% better vs. Xanax
52%
+3% better vs. Xanax
14%
+1% better vs. Xanax
767 reviews
Have you used Klonopin (clonazepam)?
Worth itNot sureNot worth it
Reviews for Valium
70%
+4% better vs. Xanax
53%
+2% better vs. Xanax
15%
+2% better vs. Xanax
976 reviews
Have you used Valium (diazepam)?
Worth itNot sureNot worth it
Reviews for Ativan
71%
+3% better vs. Xanax
51%
+4% better vs. Xanax
15%
+2% better vs. Xanax
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
Side effects
XanaxKlonopinValiumAtivan
  • Drowsiness 34%
  • Fatigue and tiredness 6%
  • Impaired coordination 23%
  • Irritability 3%
  • Memory impairment 11%
  • Increased appetite 10%
More Xanax side effects »
  • Drowsiness 50%
  • Lack of muscle coordination 30%
  • Behavior problems 25%
  • Ear, nose, or throat infection 6%
  • Fatigue 5%
  • Low mood disorder 6%
  • Dizziness 1%
  • Vaginal inflammation 3%
  • Sinus inflammation 1%
  • Inflammation inside the nose 2%
More Klonopin side effects »

The Valium FDA package insert doesn’t have numbers about how common side effects are.

More about Valium side effects »
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
How it works
XanaxKlonopinValiumAtivan
Xanax (Alprazolam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Klonopin (Clonazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.Valium (Diazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.
Type of medication
XanaxKlonopinValiumAtivan
Prescription onlyPrescription onlyPrescription onlyPrescription only
Available as
XanaxKlonopinValiumAtivan
  • Pill
  • Extended release
  • Dissolving tablet
  • Liquid
  • Pill
  • Dissolving tablet
  • Pill
  • Liquid
  • Rectal gel
  • Pill
  • Liquid
  • Injection
Used for
XanaxKlonopinValiumAtivan
Risk factors for serious side effects
XanaxKlonopinValiumAtivan
  • History of drug abuse
  • Taking with alcohol or drugs
  • Taking more than 4 mg/day or longer than 12 weeks
  • Stopping Xanax (Alprazolam) suddenly
  • Severely depressed
Detailed Xanax (alprazolam) risks & warnings »
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Alcohol
Detailed Klonopin (clonazepam) risks & warnings »
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Alcohol
Detailed Valium (diazepam) risks & warnings »
  • Taking with opioids
  • Taking more than the prescribed dose
  • Taking Ativan (lorazepam) for longer than 4 weeks
  • History of drug abuse
  • Long-term use
Detailed Ativan (lorazepam) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
XanaxKlonopinValiumAtivan
No interactions related info.No interactions related info.No interactions related info.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Alcohol
XanaxKlonopinValiumAtivan
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
Kidneys and liver
XanaxKlonopinValiumAtivan
  • Processed by the liver, so might not be the best choice if you have liver problems.
No kidneys and liver related info.
  • Processed by the liver, so might not be the best choice if you have liver problems.
No kidneys and liver related info.
Sleep
XanaxKlonopinValiumAtivan
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can cause dizziness, drowsiness, and salivation.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
Upsides and benefits
XanaxKlonopinValiumAtivan
  • Effective at relieving short-term anxiety.
  • Effective longer-term for panic attacks.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Can be used alone or with other medicines to treat seizures.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Effective at relieving muscle spasms caused by a variety of conditions.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
  • Effective at relieving short-term anxiety.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Downsides and risks
XanaxKlonopinValiumAtivan
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
  • Most people find that Ativan (lorazepam) gets less effective over time.
Tips from our pharmacists for people taking the medication
XanaxKlonopinValiumAtivan
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 45 minutes when swallowed.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
  • For the first week, avoid activities that require you to be alert.
  • Can cause dizziness, drowsiness, and salivation.
  • Report any confusion or inability to control muscle movements to your doctor.
  • Not safe to use with alcohol.
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 30 minutes when swallowed.
  • Helpful with muscle spasms.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
  • Can cause temporary dizziness and drowsiness.
  • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
  • Not safe to use with alcohol.
  • Use caution or avoid use in older adults.
Learn more
More about XanaxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Xanax (alprazolam)?
Worth itNot sureNot worth it
More about KlonopinSide effectsReviews & ratingsFDA package insert
Have you used Klonopin (clonazepam)?
Worth itNot sureNot worth it
More about ValiumSide effectsReviews & ratingsFDA package insert
Have you used Valium (diazepam)?
Worth itNot sureNot worth it
More about AtivanSide effectsReviews & ratingsFDA package insert
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it