Prescription onlyLower-cost generic available

Xyzal

(Levocetirizine)

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Treats allergy symptoms.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Xyzal (Levocetirizine) is good for treating allergy symptoms, but it can cause drowsiness.

  • Xyzal (Levocetirizine) is taken once a day to help with allergy symptoms.
  • Available as a generic in both liquid and tablets.
  • Can be taken with or without food.
  • Children can take lower doses of Xyzal (Levocetirizine).
  • Can cause drowsiness.
  • Don't take Xyzal (Levocetirizine) if you have poor kidney function.
  • Xyzal (Levocetirizine) is similar to Zyrtec, another allergy medication, so if you can't take Zyrtec, you won't be able to take Xyzal (Levocetirizine).

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Side effects for Xyzal (Levocetirizine)

From clinical trials of Xyzal / Allergies (5 mg) ( 1982)

  • DrowsinessDrowsiness6% for Levocetirizine vs.2% for placebo
  • Common coldCommon cold4% for Levocetirizine vs.3% for placebo
  • FatigueFatigue4% for Levocetirizine vs.2% for placebo
  • FeverFever4% for Levocetirizine vs.2% for placebo
  • CoughCough3% for Levocetirizine vs.0% for placebo
  • DrowsinessDrowsiness3% for Levocetirizine vs.0% for placebo
  • Dry mouthDry mouth2% for Levocetirizine vs.1% for placebo
  • NosebleedNosebleed2% for Levocetirizine vs.0% for placebo
  • Sore throatSore throat1% for Levocetirizine vs.1% for placebo

What to expect when you take Xyzal (Levocetirizine)

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Tips from our pharmacists
  • Xyzal (Levocetirizine) can cause dizziness or drowsiness. Don't drink alcohol or take other allergy medications while on this.
  • It's recommended to take Xyzal (Levocetirizine) in the evening.
  • Talk to your doctor if you experience urinary problems. You may need to switch to another allergy medication.

Risks and Warnings for Xyzal (Levocetirizine)

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    • Higher risk if:
    • Taking with alcohol
    • Taking other medicines that make you less alert

    Xyzal (Levocetirizine) lowers your ability to focus, think, and react. Be careful and avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Xyzal (Levocetirizine)

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The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Alcohol
  • Tips from our pharmacists
  • Xyzal (Levocetirizine) can cause dizziness or drowsiness. Don't drink alcohol or take other allergy medications while on this.
Food
  • Upsides and downsides from our pharmacists
  • Can be taken with or without food.
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Don't take Xyzal (Levocetirizine) if you have poor kidney function.
  • Risks from our pharmacists
  • Xyzal (Levocetirizine) is processed by the kidney. If you have kidney problems, you may need a different dose to prevent increased risk for side effects. Don't use Xyzal (Levocetirizine) if you have end-stage renal disease or are on hemodialysis. Children ages 6 months to 11 years with kidney problems shouldn't use Xyzal (Levocetirizine).
Sleep
  • Upsides and downsides from our pharmacists
  • Can cause drowsiness.
  • Tips from our pharmacists
  • Xyzal (Levocetirizine) can cause dizziness or drowsiness. Don't drink alcohol or take other allergy medications while on this.
  • Risks from our pharmacists
  • People age 65 and older have a higher risk of troublesome side effects from taking antihistamine medications like Xyzal (Levocetirizine). Watch out for changes in vision, severe dry mouth, trouble urinating, or constipation. Also, feelings of drowsiness may leave you "unsteady" on your feet. This can make you more likely to fall causing broken bones or other serious injuries. Talk with your doctor before using Xyzal (Levocetirizine) and stop using it if you have side effects.
  • Take at night to avoid potential sleepiness. Might affect my sleeping habits.
    Age: 33
    Gender: Man
    Taken for: Hives
    Duration taken: Two years or more
  • Take it at least 3 hours before bed if you won't get a full 8 hours of sleep
    Age: 26
    Gender: Woman
    Taken for: Year-round allergies