Prescription onlyLower-cost generic availableClass: Musculoskeletal

Zanaflex

(tizanidine)

Prescription onlyLower-cost generic availableClass: Musculoskeletal
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6Zanaflex

Relaxes your muscles.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Zanaflex (tizanidine) isn't a first-choice treatment for muscle spasticity. Try other options before using this.

Prices and discounts
Lowest price for 90 4mg tablets
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$21.55
  • Price before coupon
    $32.65
  • Lowest price with coupon
    $21.55
  • Savings
    34%

Upsides

  • Relieves muscle spasticity.
  • Available as a generic.
  • Available in a tablet or capsule form. It also comes in a capsule that can be opened and sprinkled in applesauce for people that can't swallow pills.
People’s experience with Zanaflex

26reviews so far. What do you think?

Worth itNot sureNot worth it

Downsides

  • This isn't a first-choice muscle relaxing medication. Other drugs work better and have fewer side effects.
  • Takes over an hour to kick in and only lasts 3 to 6 hours.
  • Zanaflex (tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication.
  • Need to be consistent every day in taking this with or without food.
  • Elderly individuals have more side effects when taking Zanaflex (tizanidine).
Prices and discounts
Lowest price for 90 4mg tablets
Determining your location...
$21.55
  • Price before coupon
    $32.65
  • Lowest price with coupon
    $21.55
  • Savings
    34%
How it works

Zanaflex (tizanidine) is an alpha2-adrenergic agonist that works in the nervous system to calm down muscle spasticity.

People’s experience with Zanaflex

26reviews so far. What do you think?

Worth itNot sureNot worth it
Dosage forms
  • Pill

What to expect when you take Zanaflex (tizanidine) for Muscle spasticity

Skip what to expect section. Skip to Risks & Warnings section.
Skip side effects section. Skip to What to Expect and Pharmacists Tips section.

Side effect rates for Zanaflex (tizanidine)

525 From clinical trials of Zanaflex / Muscle spasticity (Multiple doses)
  • Dry mouth
  • Sleepiness
  • Weakness
  • Dizziness
  • Urinary tract infection
  • General infection
  • Liver test abnormality
  • Constipation
  • Hay fever
  • Abnormal speech

Risks and Warnings for Zanaflex (tizanidine)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Taking maximum doses of Zanaflex (tizanidine)

    Zanaflex (tizanidine) can damage your liver. You'll need to get blood tests done to check how your liver is functioning if you're taking this regularly.

Common concerns from people taking Zanaflex (tizanidine)

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Food
  • Can be taken with or without food, but you need to be consistent since food affects how the medication is absorbed and works.
  • Need to be consistent every day in taking this with or without food.
Kidneys and liver
  • Watch out for signs of liver toxicity. They resolve quickly when use is topped, but can be somewhat unpleasant.
Pain
  • I took it for back pain, the pain is still there and it has not helped the pain, but I have not had a anxiety attack! This is a big thing for me as I have had them every day for years! It does not help me sleep but I am not tired.
Sleep
  • Taking Zanaflex (tizanidine) can make you feel sleepy and dizzy, especially if you're taking other medications that can also make you feel sleepy, or if you're taking recreational drugs or drinking too much alcohol. Avoid driving or doing other tasks that require concentration until you know how this medication affects you.
  • Can cause dizziness, fatigue, drowsiness, and dry mouth.
  • does cause drowsiness but since I tend to suffer from insomnia, works great at bedtime. It also works to help control breakthrough migraines.