Prescription or OTCLower-cost generic available

Zantac 75

(Ranitidine)

Prescription or OTCLower-cost generic available
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Relieves heartburn.

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Our bottom line

Zantac 75 (Ranitidine) works well for heartburn but may not last as long or start working as quickly as other antacids.

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Upsides

  • Most people can take Ranitidine without any noticeable day-to-day side effects.
  • Ranitidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Few drug interactions.
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Downsides

  • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Ranitidine.
  • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Ranitidine (H2 blockers).

What to expect when you take Zantac 75 (Ranitidine) for Reduces stomach acid

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Side effect rates for Zantac 75 (Ranitidine)

Risks and Warnings for Zantac 75 (Ranitidine)

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  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Zantac 75 (Ranitidine) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Zantac 75 (Ranitidine)

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Pregnancy
Interactions
  • Few drug interactions.
Kidneys and liver
  • People with kidney disease may need to take a lower dose.
  • Zantac 75 (Ranitidine) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose to prevent this increased risk for side effects.