Prescription or OTCLower-cost generic available

Zantac 75


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Relieves heartburn.

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Prescription or OTCLower-cost generic available

Our pharmacists’ bottom line

Zantac 75 (Ranitidine) works well for heartburn but may not last as long or start working as quickly as other antacids.

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  • Most people can take Ranitidine without any noticeable day-to-day side effects.
  • Ranitidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Few drug interactions.
  • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Ranitidine.
  • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Ranitidine (H2 blockers).

Save on your next Zantac 75 (Ranitidine) prescription

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Side effects for Zantac 75 (Ranitidine)

Manufacturers don’t say how common these side effects are

  • Abnormal heart rhythm
  • Abnormal involuntary movements
  • Abnormally large breasts in males
  • Acute interstitial nephritisgalactorrhoeaerectile dysfunction
  • Aplastic anaemia
  • Blood vessel inflammation
  • Delirium
  • Delusion
  • Dermatitis contact
  • Hair loss or baldness
  • Heart-related chest pain
  • Hepatic failure
  • Jaundice cholestatic
  • Kidney inflammation
  • Kidney inflammation
  • Liver disorder
  • Loss of libido
  • Low red blood cell count
  • Low red blood cells
  • Low white blood cells
  • Lung infection
  • Mania
  • Meningitis
  • Movement disorder
  • Movements involuntary
  • Muscle twitching
  • Rash
  • Sensitivity to light

What to expect when you take Zantac 75 (Ranitidine) for Reduces stomach acid

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Tips from our pharmacists
  • Works best if you take it with a full glass of water.
  • Starts working in one hour.
  • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
  • People with kidney disease may need to take a lower dose.

Risks and Warnings for Zantac 75 (Ranitidine)

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  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Zantac 75 (Ranitidine) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Zantac 75 (Ranitidine)

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The FDA category for this medication is B. It is advised that you: Probably safe
Kidneys and liver
  • Tips from our pharmacists
  • People with kidney disease may need to take a lower dose.
  • Risks from our pharmacists
  • Zantac 75 (Ranitidine) is processed by the kidney and liver. If you have kidney or liver problems, you may need a different dose to prevent this increased risk for side effects.