Zegerid

(omeprazole and sodium bicarbonate)

3.8/ 5 average rating with 74 reviewsforZegerid
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Relieves heartburn and excess stomach acid, and treats ulcers.

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Our bottom line

Zegerid (omeprazole and sodium bicarbonate) is an effective medicine for heartburn, but it's more expensive than buying omeprazole by itself.

Quick facts about Zegerid
  • Drug class: Gastrointestinal
  • Rx status: Prescription or OTC
  • Generic status: Lower-cost generic available (omeprazole and sodium bicarbonate)
Prices and discounts
Lowest price for 30 40mg-1100mg capsules
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$3103.61

Upsides

  • Most people can take Zegerid without any noticeable day-to-day side effects.
  • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you may only need to take it once a day.
  • Contains both a quick acting and a long acting component to help provide fast and long lasting relief.
  • Is inexpensive as both generic and over-the-counter options are availabe.

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What to expect from Zegerid, on one page

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People’s experience with Zegerid

74reviews so far. What do you think?

Downsides

  • Zegerid (omeprazole and sodium bicarbonate) contains sodium bicarbonate which isn't good if your doctor's asked you to lower your sodium bicarbonate or if you have heart or blood pressure problems.
  • May not be the best option if you have Bartter's syndrome due to sodium bicarbonate. Speak to your doctor first.
  • Should not be used for occasional heartburns. Talk to your doctor or pharmacist about other medications if you do not have frequent heartburns.

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Get our free fact sheet

What to expect from Zegerid, on one page

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Prices and discounts
Lowest price for 30 40mg-1100mg capsules
Determining your location...
$3103.61
How it works

Zegerid (omeprazole and sodium bicarbonate) is a combination of two medications: a proton pump inhibitor (omeprazole) and an antacid (sodium bicarbonate). Omeprazole stops the release of acid in your stomach. Sodium bicarbonate reduces the acidity of your stomach and allows your body to absorb more omeprazole.

Quick facts about Zegerid
  • Drug class: Gastrointestinal
  • Rx status: Prescription or OTC
  • Generic status: Lower-cost generic available (omeprazole and sodium bicarbonate)

Used for

Dosage forms

  • Pill
  • Suspension
People’s experience with Zegerid

74reviews so far. What do you think?

What to expect when you take Zegerid (omeprazole and sodium bicarbonate) for Reducing stomach acid

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Side effect rates for Zegerid (omeprazole and sodium bicarbonate)

Risks and Warnings for Zegerid (omeprazole and sodium bicarbonate)

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    • Higher risk if:
    • Elderly
    • Use during hospitalization

    Zegerid (omeprazole and sodium bicarbonate) may raise your risk of getting an infection by a bacteria called Clostridium difficile. If you experience frequent diarrhea, abdominal pain, fevers, and loss of appetite speak to your doctor right away. Your doctor may need to switch you to a different medication as well as treat your infection.

Common concerns from people taking Zegerid (omeprazole and sodium bicarbonate)

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Interactions
  • Certain drugs may interact with Zegerid (omeprazole and sodium bicarbonate). Let your doctor or pharmacist know if you're currently taking other medications.