Prescription or OTCLower-cost generic availableClass: Gastrointestinal

Zegerid Alternatives

(omeprazole / sodium bicarbonate)

Prescription or OTCLower-cost generic availableClass: Gastrointestinal
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Compare Zegerid (omeprazole / sodium bicarbonate) to alternatives

These medications are comparable to Zegerid (omeprazole / sodium bicarbonate) or used for similar purposes.

Zegerid
(omeprazole / sodium bicarbonate)

Nexium
(esomeprazole)

Alka-Seltzer Original
(aspirin / citric acid / sodium bicarbonate)

Pepcid
(famotidine)

Rolaids
(calcium carbonate / magnesium hydroxide)

Prilosec
(omeprazole)

Tums
(calcium carbonate)

Maalox
(aluminum / magnesium / simethicone)

Zantac 75
(ranitidine)

Tagamet
(cimetidine)

Protonix
(pantoprazole)

Relieves heartburn, ulcers, and acid tummy. Zegerid (Omeprazole / Sodium Bicarbonate) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Treats heartburn and stomach ulcers. Nexium (esomeprazole) gives you long-lasting heartburn relief but has some risks if used long term.Relieves heartburn, headache, and body pains. Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) gives quick relief for headache, body pains, and upset tummies, but might be hard to swallow if you don't like the taste or fizz.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn and acid tummy. Rolaids (Calcium Carbonate / Magnesium Hydroxide) gives quick relief for heartburn, but don't expect it to last all day.Treats heartburn and stomach ulcers. Prilosec (Omeprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.Relieves heartburn and indigestion. Maalox (aluminum / magnesium / simethicone) gives quick relief for heartburn, gas, and bloating, but it may not be as effective or last as long as other antacids.Relieves heartburn and stomach ulcers. Zantac 75 (ranitidine) is an effective and inexpensive medicine for hearburn with few side effects, but may interfere with other drugs.Treats heartburn. Tagamet (cimetidine) works well for heartburn, but may have more side effects than other medicines like it.Treats heartburn and excess release of stomach acid. Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.24Zegerid
Reviews for Zegerid
72%
of people (All ages) say Zegerid is worth it
55%
say it works well
12%
say it's a big hassle
Have you used Zegerid (omeprazole / sodium bicarbonate)?
Worth itNot sureNot worth it
Reviews for Nexium
75%
-3% worse vs. Zegerid
59%
-4% worse vs. Zegerid
11%
-1% worse vs. Zegerid
1239 reviews
Have you used Nexium (esomeprazole)?
Worth itNot sureNot worth it
Reviews for Alka-Seltzer
81%
-9% worse vs. Zegerid
52%
+3% better vs. Zegerid
8%
-4% worse vs. Zegerid
1055 reviews
Have you used Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate)?
Worth itNot sureNot worth it
Reviews for Pepcid
75%
-3% worse vs. Zegerid
41%
+14% better vs. Zegerid
8%
-4% worse vs. Zegerid
853 reviews
Have you used Pepcid (famotidine)?
Worth itNot sureNot worth it
Reviews for Rolaids
75%
-3% worse vs. Zegerid
37%
+18% better vs. Zegerid
7%
-5% worse vs. Zegerid
1089 reviews
Have you used Rolaids (calcium carbonate / magnesium hydroxide)?
Worth itNot sureNot worth it
Reviews for Omeprazole
80%
-8% worse vs. Zegerid
59%
-4% worse vs. Zegerid
8%
-4% worse vs. Zegerid
1167 reviews
Have you used Prilosec (omeprazole)?
Worth itNot sureNot worth it
Reviews for Tums
82%
-10% worse vs. Zegerid
43%
+12% better vs. Zegerid
5%
-7% worse vs. Zegerid
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Reviews for Maalox
69%
+3% better vs. Zegerid
30%
+25% better vs. Zegerid
9%
-3% worse vs. Zegerid
213 reviews
Have you used Maalox (aluminum / magnesium / simethicone)?
Worth itNot sureNot worth it
Reviews for Zantac
72%
Same vs. Zegerid
44%
+11% better vs. Zegerid
7%
-5% worse vs. Zegerid
1062 reviews
Have you used Zantac 75 (ranitidine)?
Worth itNot sureNot worth it
Reviews for Tagamet
63%
+9% better vs. Zegerid
36%
+19% better vs. Zegerid
12%
Same vs. Zegerid
632 reviews
Have you used Tagamet (cimetidine)?
Worth itNot sureNot worth it
Reviews for pantoprazole
68%
+4% better vs. Zegerid
51%
+4% better vs. Zegerid
13%
+1% better vs. Zegerid
584 reviews
Have you used Protonix (pantoprazole)?
Worth itNot sureNot worth it
Side effects
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole

The Zegerid FDA package insert doesn’t have numbers about how common side effects are.

More about Zegerid side effects »

The Nexium FDA package insert doesn’t have numbers about how common side effects are.

More about Nexium side effects »

We haven’t found good data for Alka-Seltzer side effects.

FDA side effect reports for Alka-Seltzer »
  • Headache 5%
  • Diarrhea 2%
More Pepcid side effects »

We haven’t found good data for Rolaids side effects.

FDA side effect reports for Rolaids »
  • Upper respiratory infection 75%
  • Fever 33%
  • Headache 7%
  • Abdominal pain 5%
  • Nausea 4%
  • Diarrhea 4%
  • Accidental injuries 4%
  • Passing gas 3%
  • Vomiting 3%
More Omeprazole side effects »

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »

The Maalox FDA package insert doesn’t have numbers about how common side effects are.

More about Maalox side effects »

The Zantac FDA package insert doesn’t have numbers about how common side effects are.

More about Zantac side effects »
  • Headache 2%
More Tagamet side effects »
  • Headache 3%
  • Diarrhea 4%
  • Vomiting 2%
  • Dizziness 2%
  • Joint pain 2%
More pantoprazole side effects »
How it works
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
Zegerid (Omeprazole / Sodium Bicarbonate) is a type of antacid called a proton pump inhibitor. It blocks the release of acid in your stomach, which treats heartburn and helps ulcers heal.Nexium (esomeprazole) is a proton pump inhibitor (PPI). It treats heartburn and heals ulcers by lowering the amount of acid in your stomach.Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) is a combination medicine. Sodium bicarbonate is an antacid that relieves heartburn and acid tummy (indigestion). Aspirin is a pain reliever that treats headache and body pains.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Rolaids (Calcium Carbonate / Magnesium Hydroxide) is an antacid. It counteracts the effects of stomach acid to relieve heartburn and acid tummy (indigestion).Prilosec (Omeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.Maalox (aluminum / magnesium / simethicone) is a combination medicine for heartburn and indigestion. Aluminum and magnesium are antacids that treat heartburn and indigestion. Simethicone relieves gas and bloating.Zantac 75 (ranitidine) reduces the production of acid by blocking a chemical from acting on the acid-producing cells in your stomach.Tagamet (cimetidine) reduces acid production in your stomach.Protonix (pantoprazole) is a proton pump inhibitor. It lowers the amount of acid in your stomach which treats heartburn.
Type of medication
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
Prescription or OTCOver-the-counterOver-the-counterPrescription or OTCOver-the-counterPrescription or OTCOver-the-counterOver-the-counterPrescription or OTCPrescription or OTCPrescription only
Available as
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
  • Pill
  • Pill
  • Injection
  • Packet
  • Chewable tablet
  • Effervescent tablet
  • Pill
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
  • Extended release
  • Chewable tablet
  • Liquid
  • Chewable tablet
  • Liquid
  • Pill
  • Oral solution
  • Oral syrup
  • Injection
  • Pill
  • Liquid
  • Pill
  • Packet
Used for
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
  • GERD
  • H Pylori Bacterial Infection
Risk factors for serious side effects
ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Zegerid (omeprazole / sodium bicarbonate) risks & warnings »
  • Being treated at a hospital
  • High dose Nexium (esomeprazole)
  • Long-term treatment with Nexium (esomeprazole)
  • Low bone mineral density
  • Aged 65 years or older
Detailed Nexium (esomeprazole) risks & warnings »
  • Current kidney disease
  • Kidney dialysis
  • Age 65 or older
  • Congestive heart failure (CHF)
  • High blood pressure
Detailed Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) risks & warnings »
  • Current kidney disease
Detailed Pepcid (famotidine) risks & warnings »
  • Current kidney disease
  • Kidney dialysis
  • Hyperparathyroid disease
  • Taking high doses of Vitamin D
  • Previous kidney stones
Detailed Rolaids (calcium carbonate / magnesium hydroxide) risks & warnings »
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Prilosec (omeprazole) risks & warnings »
    Coming soon.
    • Kidney problems
    • Taking more than the recommended daily maximum
    Detailed Maalox (aluminum / magnesium / simethicone) risks & warnings »
    • Aged 60 years or older
    • Kidney conditions
    • Liver conditions
    • Acute Porphyria
    • Asthma
    Detailed Zantac 75 (ranitidine) risks & warnings »
    • Elderly
    • Kidney problems
    • Liver problems
    • Dementia
    • Asthma
    Detailed Tagamet (cimetidine) risks & warnings »
    • Using multiple daily doses and/or for 1 year or longer
    • People age 65 or older
    • High risk of bone fractures
    • People who are being treated in the hospital
    • People with lupus
    Detailed Protonix (pantoprazole) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
    • Since some prescription drugs can interact with Nexium (esomeprazole), talk to your doctor about all the medicines that you're taking.
    No interactions related info.
    • Few drug interactions.
    No interactions related info.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
    No interactions related info.No interactions related info.
    • Zantac 75 (ranitidine) can interact with certain prescription and over-the-counter medications. Let your doctor or pharmacist know about the medicines you are currently taking.
    No interactions related info.No interactions related info.
    Alcohol
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
    • The syrup product may contain up to 7.5% of alcohol.
    No alcohol related info.No alcohol related info.
    Food
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    • Take 1 hour before a meal.
    No food related info.
    • Take it with food to lower the chance of an upset stomach.
    No food related info.No food related info.
    • Take 1 hour before a meal.
    No food related info.
    • Talk to your doctor or pharmacist about foods to avoid that can help prevent heartburn.
    No food related info.No food related info.
    • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
    Kidneys and liver
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    No kidneys and liver related info.
    • Nexium (esomeprazole) can cause acute kidney damage that can occur at any time during treatment. If you notice blood in the urine, changes in urine output, swelling of the body, weight gain, fever, or confusion, stop taking Nexium (esomeprazole) and speak to your doctor immediately.
    • If you have kidney or hyperparathyroid disease Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate) can build up in your blood. This may can cause toxic levels of sodium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Alka-Seltzer Original (Aspirin / Citric Acid / Sodium Bicarbonate); a different antacid would be better for you.
    • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • If you have kidney or hyperparathyroid disease Rolaids (Calcium Carbonate / Magnesium Hydroxide) can build up in your blood. This may can cause toxic levels of calcium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Rolaids (Calcium Carbonate / Magnesium Hydroxide); a different antacid would be better for you.
    • Rolaids (Calcium Carbonate / Magnesium Hydroxide) contains calcium. Calcium can be an ingredient in some kidney stones. If you have had kidney stones in the past (especially the calcium-containing kind) be careful using Rolaids (Calcium Carbonate / Magnesium Hydroxide). Use the lowest dose for the shortest time possible or just play it safe and use a different antacid instead.
    • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
    No kidneys and liver related info.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • Maalox (aluminum / magnesium / simethicone) contains aluminum and magnesium that can build up in your kidneys if you have kidney problems which can be dangerous. Talk to your doctor or pharmacist before taking Maalox (aluminum / magnesium / simethicone) to see if it is right for you. Don't take more than the maximum amount per day as shown on the label.
    No kidneys and liver related info.
    • Tagamet (cimetidine) can cause confusion if you have kidney or liver problems, dementia, or if you are over 60 years old. Talk to your doctor or pharmacist about alternative medicines if you have any of these conditions.
    • May not be the best option if you are elderly or have kidney or liver problems.
    • Protonix (pantoprazole) can very rarely damage your kidneys. This can happen at any time. Talk to your doctor right away if you are urinating less or have blood in the urine.
    Pain
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
    • Talk to your doctor if you get watery diarrhea, fever, or stomach pain that don't go away after taking Protonix (pantoprazole), which can happen even 2 months after stopping the medicine.
    Upsides and benefits
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    • Most people can take Zegerid without any noticeable day-to-day side effects.
    • Zegerid lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Most people can take Nexium (esomeprazole) without any noticeable day-to-day side effects.
    • Nexium (esomeprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need quicker relief.
    • Nexium (esomeprazole) is inexpensive, with over-the-counter and generic options.
    • Coupons are available for the brand name - speak to your doctor or pharmacist.
    • The packet form is a good option if you have trouble swallowing pills.They can be mixed with water for easier swallowing.
    • Works great if you have an upset stomach and a headache or body pain at the same time.
    • Works really fast.
    • Available over the counter without a prescription.
    • Cheap.
    • Most people can take Famotidine without any noticeable day-to-day side effects.
    • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Few drug interactions.
    • Works really fast.
    • Available over the counter without a prescription.
    • Cheap.
    • Most people can take Omeprazole without any noticeable day-to-day side effects.
    • Omeprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    • Works quickly.
    • Inexpensive and available over-the-counter.
    • Is one of the first choice medications for heartburn relief if you are pregnant.
    • Zantac 75 (ranitidine) works well to relieve heartburn symtoms and is quite tolerable.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • If you have trouble swallowing pills you may find the liquid product a good option.
    • Inexpensive with over-the-counter and generic options.
    • Coupons are available for the brand product - speak to your doctor or pharmacist.
    • Lasts longer than other medicines like it so you may not need to take it as frequently.
    • Affordable as an over-the-counter or generic medicine.
    • Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
    • Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
    • You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
    • Can be used in children age 5 or older.
    Downsides and risks
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Zegerid long-term.
    • Although the generic is affordable, other medications might still be cheaper than Zegerid.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Zegerid.
    • Doesn't start working right away like antacids (Tums, Rolaids, or Maalox).
    • It can take several days or weeks to start feeling benefits.
    • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and severe diarrhea.
    • Doesn't last very long.
    • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
    • Because it has aspirin in it, it increases the risk of bleeding, especially if you take any other blood thinning medicine.
    • Can't be used by people with allergy to aspirin.
    • You may not like the taste or fizz.
    • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
    • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    • Doesn't last very long.
    • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
    • Some chalky aftertaste.
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Omeprazole long-term.
    • Although the generic is affordable, other medications might still be cheaper than Omeprazole.
    • Can interact with other drugs so be sure your doctor knows all the medicine you're taking before starting Omeprazole.
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    • Doesn't last very long. Talk to your doctor or pharmacist if you need longer lasting relief.
    • Is not a good option if you have frequent symptoms (more than 2 times a week). Talk to your doctor or pharmacist about stronger medications.
    • Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. Speak to your doctor or pharmacist if you need quicker relief.
    • Zantac 75 (ranitidine) does not last as long as some other acid reducers. Speak to your doctor or pharmacist if you need longer relief.
    • May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. Your doctor will assess which medication is best for you.
    • Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. Your doctor can order lab tests to monitor your vitamin B12 levels.
    • Does not work as fast as antacids like Maalox, Tums, or Rolaids.
    • May not work as well if you have an inflammed esophagus. Your doctor will assess which medicine is best for you.
    • May not be the best option if you are elderly or have kidney or liver problems.
    • Can interfere with how other medicines work.
    • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
    • Needs to be taken every single day for a certain period of time to be effective.
    • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
    • Only available as a prescription medicine, not over the counter.
    • Can lower the magnesium level in your body so you may need to take a supplement for it.
    Tips from our pharmacists for people taking the medication
    ZegeridNexiumAlka-SeltzerPepcidRolaidsOmeprazoleTumsMaaloxZantacTagametpantoprazole
    • Take 1 hour before a meal.
    • Don't chew or crush capsules; swallow them whole.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Zegerid.
    • If you've been having heartburn for 3 months or more, talk to your doctor before taking Zegerid. Get a check-up to make sure you aren't having a more serious stomach problem.
    • Talk to your doctor if you're still having heartburn after two weeks of use. Don't keep taking Zegerid; get checked-out first.
    • Take Nexium (esomeprazole) with a full glass of water 1 hour before eating.
    • Starts working in as little as an hour.
    • It can take 1 to 4 days to take full effect.
    • Since some prescription drugs can interact with Nexium (esomeprazole), talk to your doctor about all the medicines that you're taking.
    • Do not take Nexium (esomeprazole) for more than 14 days, unless directed by your doctor. Speak to your doctor if your symptoms don't go away after 2 weeks.
    • Nexium (esomeprazole) capsules can be opened and sprinkled on 1 tablespoon of applesauce, cottage cheese, or yogurt. Swallow immediately after.
    • Don't take Alka-Seltzer if you're allergic to aspirin.
    • Take it with food to lower the chance of an upset stomach.
    • This medicine isn't recommended for kids 12 and younger because it has aspirin in it.
    • Stop taking this right away and talk to your doctor if you have ringing in your ears, rash, trouble breathing, unusual bleeding, or nausea or vomiting that doesn't go away.
    • Having a dental or medical procedure? You may need to stop taking this before the big day. Ask your dentist or doctor.
    • Alka-Seltzer contains sodium. If you need to follow a low sodium diet a different medication would be better for you.
    • Not a good choice if you have stomach bleeding, bleeding problems, diabetes, or gout, or if you're taking medicines to thin your blood.
    • Short-term treatment of ulcers and acid reflux.
    • Take at the first sign of discomfort.
    • You might need to take more than once a day but pay attention to the instructions on your bottle to avoid overdosing.
    • Take 1-2 hours apart from other medication that you take by mouth.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
    • Don't take if you have high blood calcium levels.
    • Take 1 hour before a meal.
    • Don't chew or crush capsules; swallow them whole.
    • If you have trouble swallowing you can carefully open the capsules and sprinkle the inside pellets onto applesauce. Swallow the applesauce without chewing or crushing the pellets.
    • When using Omeprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
    • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Omeprazole.
    • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Omeprazole.
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    • Starts working within minutes, and lasts for 1-2 hours.
    • If you are using the liquid product, shake well before using.
    • Don't take more than the recommended amount per day on the package. If you need to take this for more than 2 weeks, talk to your doctor.
    • People on a magnesium-restricted diet may need to avoid Maalox. Ask your doctor.
    • Talk to your doctor or pharmacist about foods to avoid that can help prevent heartburn.
    • Eating smaller portion sizes and not eating 3 hours before bedtime can help prevent heartburn.
    • To prevent a heartburn attack, take Zantac 75 (ranitidine) 30 minutes before eating.
    • Works within 30 to 60 minutes. Relief lasts up to 12 hours.
    • Do not use Zantac 75 (ranitidine) for more than 14 days. Talk to your doctor if your symptoms do not improve after 2 weeks of using the over-the-counter product, as this may indicate a more serious problem.
    • The syrup product may contain up to 7.5% of alcohol.
    • Speak to your doctor or pharmacist about lifestyle and dietary changes that can help prevent heartburn.
    • Take 30 minutes before eating for maximum heartburn relief.
    • Talk to your doctor if you don't see any improvement after 2 weeks.
    • Talk to your doctor if you end up using this medicine more than 2 times a week.
    • Let your doctor or pharmacist know about any other medicines or supplements that you are taking because Tagamet (cimetidine) can interfere with how a lot of other medicines work.
    • Take the tablet form of Protonix (pantoprazole) with or without food.
    • The medicine should be swallowed whole and not to to be chewed or crushed.
    • Protonix (pantoprazole) takes some time to kick in, about 2.5 hours after taking it.
    • The oral suspension form needs to be prepared and then taken 30 minutes before a meal. The contents of the packet for the suspension shouldn't be crushed or chewed and be taken in apple juice or applesauce only as stated in the instructions.
    • Talk to your doctor if you get watery diarrhea, fever, or stomach pain that don't go away after taking Protonix (pantoprazole), which can happen even 2 months after stopping the medicine.
    • Using this medicine for a long period of time can increase your risk of getting weaker bones. Talk to your doctor if you are worried about this possible long-term side effect.
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