Prescription onlyClass: Cardiovascular



Prescription onlyClass: Cardiovascular
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Lowers cholesterol.

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Our bottom line

Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.

Price and discounts
Prices and coupon for 30 (10mg) tablets of ezetimibe


  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
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  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, Zetia is not as effective as statins for improving cholesterol.
  • There's no generic available, so it can be expensive.
How it works

Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.

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Side effect rates for Zetia (ezetimibe)

3555 From clinical trials of Zetia / High cholesterol
  • Diarrhea
  • Ear, nose, or throat infection
  • Sinus inflammation
  • Arthtralgia
  • Pain in extremity
  • Fatigue
  • Flu

Risks and Warnings for Zetia (ezetimibe)

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  • Talk to your doctor if you are planning to become pregnant or are pregnant, as Zetia (Ezetimibe) can cause birth defects up to death of the fetus. Your doctor will discuss alternatives for you.

Common concerns from people taking Zetia (ezetimibe)

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Kidneys and liver
  • Reports of liver disease have been reported in people who take Zetia (Ezetimibe), especially if taken with statins. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.