Prescription onlyLower-cost generic availableClass: Neuro/psych

Zonegran

(zonisamide)

Prescription onlyLower-cost generic availableClass: Neuro/psych
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Controls partial seizures.

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Our bottom line

Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can't be used by itself.

Prices and discounts
Lowest price for 60 100mg capsules
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$16.87
  • Price before coupon
    $129.77
  • Lowest price with coupon
    $16.87
    87% savings

Upsides

  • Available in generic.
  • Can be given once a day, so it's easier to remember.
  • You can take Zonegran (zonisamide) with or without food.
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Downsides

  • Zonegran (zonisamide) has to be used with other medicines to help control your seizures. It's not used by itself.
  • Zonegran (zonisamide) is only approved in people age 16 or older.
  • Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
  • Zonegran (zonisamide) can weaken your bones. Talk to your doctor about how to keep your bones strong.
  • Other medicines used to control seizures can interact with Zonegran (zonisamide), so your doctor might have to change the dosing of your medications.
Prices and discounts
Lowest price for 60 100mg capsules
Determining your location...
$16.87
  • Price before coupon
    $129.77
  • Lowest price with coupon
    $16.87
    87% savings
How it works

Zonegran (zonisamide) is a sulfonamide. It's not exactly clear how it controls seizures, but it stops nerves from sending signals that can cause seizures.

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Dosage forms
  • Pill

What to expect when you take Zonegran (zonisamide) for Partial seizures

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Side effect rates for Zonegran (zonisamide)

499 From clinical trials of Zonegran / Partial seizures
  • Sleepiness
  • Loss of appetite
  • Dizziness
  • Headache
  • Nausea
  • Agitation or irritability
  • Fatigue
  • Tiredness
  • Trouble sleeping
  • Low mood disorder

Risks and Warnings for Zonegran (zonisamide)

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    • Higher risk if:
    • Allergy to sulfonamides such as Septra or Bactrim

    If you're allergic to sulfa medicines, don’t take Zonegran (zonisamide), since you might have a severe allergic reaction. Talk to your doctor or go to the emergency room right away if you notice a skin rash, high fever, or severe pain in your stomach.

Common concerns from people taking Zonegran (zonisamide)

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Alcohol
  • Be very careful drinking alcohol or taking medicines for pain or anxiety while taking Zonegran (zonisamide) because your breathing can become dangerously slow.
Food
  • You can take Zonegran (zonisamide) with or without food.
Kidneys and liver
  • Rarely, Zonegran (zonisamide) can cause changes to the acid balance in your blood. If not treated in time, it can cause kidney stones, or weaken your bones and make them likely to fracture. Your doctor might do regular blood tests to make sure you're healthy.
  • Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
Pain
  • If you're allergic to sulfa medicines, don’t take Zonegran (zonisamide), since you might have a severe allergic reaction. Talk to your doctor or go to the emergency room right away if you notice a skin rash, high fever, or severe pain in your stomach.