Prescription onlyLower-cost generic availableClass: Mental health

Zyprexa 

(olanzapine)

Prescription onlyLower-cost generic availableClass: Mental health
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Helps control your thoughts and mood.

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Our bottom line

Zyprexa (Olanzapine) is good for treating psychosis, mania, and agitation. More likely to cause weight gain and sleepiness than other antipsychotics.

Price and discounts
Best available price for 30 (5mg) tablets of olanzapine

Upsides

  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Lowers relapse rates for schizophrenia and bipolar disorder.
  • Antipsychotic medicines are all about equally effective.
  • Less likely to cause heart problems than some antipsychotics.
People say this drug is:
68 reviews

Downsides

  • More likely to cause weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
How it works

Zyprexa (Olanzapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.

What to expect when you take Zyprexa (olanzapine) for Schizophrenia

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Side effect rates for Zyprexa (olanzapine)

161 From clinical trials of Zyprexa / Adolescent bipolar I disorder (13 to 17 years old) (≥ 2.5 mg per day)
  • Relaxation or sleepiness
  • Weight increase
  • Increased appetite
  • Headache
  • Fatigue
  • Dizziness
  • Dry mouth
  • Abdominal pain
  • Pain in extremity

Risks and Warnings for Zyprexa (olanzapine)

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    • Higher risk if:
    • Elderly patients with dementia

    Older patients with dementia-related psychosis have a higher risk of death when treated with antipsychotic medications. Zyprexa (Olanzapine) is not approved to treat dementia-related psychosis.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Zyprexa (olanzapine)

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Pregnancy
Food
  • Zyprexa (Olanzapine) can increase your blood sugar and cholesterol. Zyprexa (Olanzapine) is more likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Zyprexa (Olanzapine) can cause you to gain weight. Zyprexa (Olanzapine) is more likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • WEIGHT GAIN No control over appetite, craved salty and sweet food only/ Started to abuse laxatives . This was only 1.25mg dosage. Bad drug for me. And diabetes does not appeal to me.
Sleep
  • Might make you more sleepy than some antipsychotics.
  • Can cause dizziness and drowsiness.
  • I love sleep and I found out this med makes you sleep but then I got addicted to it the withdrawals are debilitating pysical and mental
Weight
  • More likely to cause weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Zyprexa (Olanzapine) can cause you to gain weight. Zyprexa (Olanzapine) is more likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Huge huge huge weight gain. Uncontrollable and absolutely ridiculous. Also, terrible tremors and the withdrawls are terrible, sweating a lot, lot of body odor. Terrible, not worth it because of the serious side effects.
  • Massive weight gain, never felt such a compulsion to eat. However, it is great to take for a day or two on top of Quetiapine and Lamotrigine to control serious anxiety att I.
  • definitely weight gain