Prescription onlyClass: Cancer

Zytiga

(abiraterone)

Prescription onlyClass: Cancer
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Treats prostate cancer.

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Our bottom line

Zytiga (Abiraterone) is an effective, first-line option for a certain type of prostate cancer, but it has many drug interactions and may be expensive.

Price and discounts
Prices and coupon for 120 (250mg) tablets of abiraterone

Upsides

  • In studies, people with a certain type of prostate cancer taking Zytiga (Abiraterone) lived longer by about 4 months and the cancer didn't worsen by about 2 months.
  • In studies, people with a certain type of prostate cancer taking Zytiga (Abiraterone) delayed starting chemotherapy by about 8 months.
  • Treats metastatic, castration-resistant prostate cancer (mCRPC).
  • Zytiga (Abiraterone) is an oral tablet that's taken once a day.

Downsides

  • Not the best choice if you have heart or liver problems.
  • Zytiga (Abiraterone) can cause liver damage. You'll need routine blood tests to check your liver function.
  • There are many drug interactions.
  • There's no generic available and it can be very expensive.
How it works

Zytiga (Abiraterone) is an antiandrogen. It stops tumor growth by binding to a specific enzyme in cancer cells and blocking the formation of testosterone.

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Side effect rates for Zytiga (abiraterone)

1185 From clinical trials of Zytiga / Prostate cancer, all grades (1000 mg (taken with 5 mg Prednisone twice a day))
  • High blood triglycerides
  • High blood sugar
  • High alt
  • Fatigue
  • Lymphopenia
  • High ast
  • High blood sodium
  • High ast
  • Joint swelling/discomfort
  • Low blood potassium

Risks and Warnings for Zytiga (abiraterone)

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    • Higher risk if:
    • Current liver problems

    Zytiga (Abiraterone) is processed by the liver. If you have liver problems, talk to your doctor because you may need a different dose. Baseline and follow-up lab tests are needed before starting Zytiga (Abiraterone).

Common concerns from people taking Zytiga (abiraterone)

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Pregnancy
Interactions
  • There are many drug interactions.
  • Zytiga (Abiraterone) interacts with a lot of medicines. Talk to your doctor or pharmacist before starting Zytiga (Abiraterone) or any other new medicine.
Food
  • Zytiga (Abiraterone) must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after taking Zytiga (Abiraterone).
Kidneys and liver
  • Not the best choice if you have heart or liver problems.
  • Zytiga (Abiraterone) can cause liver damage. You'll need routine blood tests to check your liver function.
  • Zytiga (Abiraterone) is processed by the liver. If you have liver problems, talk to your doctor because you may need a different dose. Baseline and follow-up lab tests are needed before starting Zytiga (Abiraterone).
  • Adrenal suppression may occur if you get an infection, are under stress, or stop taking prednisone. Tell your doctor if you notice any fatigue, dizziness, loss of appetite, nausea, vomiting, diarrhea, or muscle aches.