Prescription onlyNo lower cost generic available

Zytiga Alternatives

(Abiraterone)

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Compare Zytiga (Abiraterone) to alternatives

These medications are comparable to Zytiga (Abiraterone) or used for similar purposes.

Zytiga
(Abiraterone)

Casodex
(Bicalutamide)

Flutamide

Treats prostate cancer. Zytiga (Abiraterone) is an effective, first-line option for a certain type of prostate cancer, but it has many drug interactions and may be expensive.Coming soon.Coming soon.
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Reviews & ratings
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Side effects
ZytigaCasodexflutamide
  • High alt 13%
  • High blood triglycerides 10%
  • Swelling due to excess fluid 9%
  • High blood pressure 9%
  • High ast 8%
  • High blood sodium 8%
  • Low blood potassium 8%
  • Low blood phosphate 8%
  • Joint swelling/discomfort 7%
  • Lymphopenia 6%
More Zytiga side effects »

We haven’t found good data for Casodex side effects.

FDA side effect reports for Casodex »

We haven’t found good data for flutamide side effects.

FDA side effect reports for flutamide »
How it works
ZytigaCasodexflutamide
Zytiga (Abiraterone) is an antiandrogen. It stops tumor growth by binding to a specific enzyme in cancer cells and blocking the formation of testosterone.Coming soon.Coming soon.
Type of medication
ZytigaCasodexflutamide
Anticancer
Antiandrogen
Prescription only
Coming soon.
Coming soon.
Available as
ZytigaCasodexflutamide
  • Pill
  • Pill
  • Pill
Used for (click to learn more)
ZytigaCasodexflutamide
  • Metastatic prostate cancer
  • Carcinoma of prostate
Risk factors for serious side effects
ZytigaCasodexflutamide
  • Current liver problems
  • History of high blood pressure
  • Infection
  • Stress
  • Stop taking prednisone
  • History of cardiovascular disease
  • Women of childbearing age
Detailed Zytiga (Abiraterone) risks & warnings »
Coming soon.Coming soon.
Pregnancy category
ZytigaCasodexflutamide
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
Food
  • Zytiga (Abiraterone) must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after taking Zytiga (Abiraterone).
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.No specific weight-related info.
Upsides and benefits
ZytigaCasodexflutamide
  • In studies, people with a certain type of prostate cancer taking Zytiga (Abiraterone) lived longer by about 4 months and the cancer didn't worsen by about 2 months.
  • In studies, people with a certain type of prostate cancer taking Zytiga (Abiraterone) delayed starting chemotherapy by about 8 months.
  • Treats metastatic, castration-resistant prostate cancer (mCRPC).
  • Zytiga (Abiraterone) is an oral tablet that's taken once a day.
Coming soon.Coming soon.
Downsides and risks
ZytigaCasodexflutamide
  • Not the best choice if you have heart or liver problems.
  • Zytiga (Abiraterone) can cause liver damage. You'll need routine blood tests to check your liver function.
  • There are many drug interactions.
  • There's no generic available and it can be very expensive.
Coming soon.Coming soon.
Tips from our pharmacists for people taking the medication
ZytigaCasodexflutamide
  • Zytiga (Abiraterone) must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after taking Zytiga (Abiraterone).
  • Don't crush or chew Zytiga (Abiraterone). Swallow the tablets whole with a glass of water.
  • Each dose of Zytiga (Abiraterone) must be taken with a medicine called prednisone. This is to help lower the side effects you might experience with Zytiga (Abiraterone).
  • Zytiga (Abiraterone) can cause birth defects. Men should use a condom and another form of birth control during treatment and for 1 week after. Women who are or may be pregnant shouldn't touch the tablets without gloves.
  • Zytiga (Abiraterone) interacts with a lot of medicines. Talk to your doctor or pharmacist before starting Zytiga (Abiraterone) or any other new medicine.
Coming soon.Coming soon.
Learn more
More about ZytigaSide effectsReviews & ratingsAlternativesFDA package insert
More about CasodexSide effectsReviews & ratingsFDA package insert
More about flutamideSide effectsFDA package insert