Compare Abilify vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Abilify (aripiprazole)

Prescription only

Latuda (lurasidone)

Prescription only
Helps control your thoughts and mood.

Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.

3.2/ 5 average rating with 252 reviewsforAbilify
Helps control your thoughts and mood.

Latuda (lurasidone) is good for treating schizophrenia and depression related to bipolar disorder, but can cause sleepiness and movement disorders that can affect your ability to stay alert.

3.8/ 5 average rating with 61 reviewsforLatuda
Upsides
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
  • Has been shown in clinical studies to help people experience improvement in their thoughts and mood.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotic medicines, Latuda (lurasidone) has a lower risk of causing weight gain, high cholesterol, high blood sugar, and heart rhythm changes.
Downsides
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
  • It may take several weeks before you feel the full effects of Latuda (lurasidone).
  • You may get more side effects if you're taking certain antifungal and heart medicines.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (lurasidone).
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
Price
Lowest price
$2434.34
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Lowest price
$1223.39
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Reviews
252 reviews so far
44%
saidit'sworth it
40%
saiditworked well
34%
saidit'sa big hassle

Have you used Abilify (aripiprazole)?

Leave a review
61 reviews so far
61%
saidit'sworth it
61%
saiditworked well
25%
saidit'sa big hassle

Have you used Latuda (lurasidone)?

Leave a review
Side effects
4possible side effects
  • Restlessness
    13%
  • Sedation
    8%
  • Tremor
    6%
  • Difficulty controlling movements
    5%
See more detailed side effects
12possible side effects
  • Nausea
    14%
  • Sleepiness
    11%
  • Restlessness
    9%
  • Movement disorder
    7%
  • Dry mouth
    5%
  • Vomiting
    4%
  • Diarrhea
    4%
  • Common cold
    4%
  • Anxiety
    4%
  • Flu
    2%
  • Urinary tract infection
    2%
  • Back pain
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
    • Age 24 years or younger
    • Use of antidepressant medications
  • Shaking and restlessness
  • Increased blood sugar and cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Low blood pressure
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Abnormal and involuntary muscle movements
    • Taking Latuda (lurasidone) in higher doses or for a long time
    • Elderly
    • Female
  • Low blood pressure
    • Dehydration
    • Taking blood pressure medications
  • Sedation and driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Low white blood cells
See more detailed risks and warnings