Compare Abilify vs. Saphris
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control your thoughts and mood.
Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.
●●●●●
3.2/ 5 average rating with 252 reviewsforAbilify
Treats bipolar disorder and schizophrenia.
While Saphris (asenapine) has fewer side effects compared with other medicines that treat bipolar disorder and schizophrenia, it can be more expensive.
Upsides
- Effective at relieving psychotic symptoms and manic episodes.
- More energizing than other antipsychotics.
- Fewer side effects than other antipsychotics.
- Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
- Available as a generic, which is cheaper.
- Saphris (asenapine) can be used to treat bipolar disorder in children age 10 or older, and schizophrenia in children age 12 or older.
- You don't need water to take Saphris (asenapine); the pill dissolves in your mouth right away.
- Compared to other medicines, the side effects of Saphris (asenapine) are milder.
Downsides
- Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
- You might need routine blood tests to check how the medicine is affecting your body.
- All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
- Saphris (asenapine) is only available as a brand name.
- Compared to other medicines, Saphris (asenapine) can cause changes in your hormones and make you sleepy.
- You have to take Saphris (asenapine) twice a day, which can be hard to remember.
Used for
- Schizophrenia
- Bipolar I disorder
- Depression
- Autistic disorder irritability
- Tourette syndrome
Dosage forms
- Pill
- Dissolving tablet
- Liquid
- Injection
- Dissolving pill
Price
Lowest price
$2715.90
Find instant savings near youLowest price
$600.64
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
252 reviews so far
44%
saidit'sworth it
40%
saiditworked well
34%
saidit'sa big hassle
Have you used Abilify (aripiprazole)?
Leave a reviewNot enough review data.Leave a review
Side effects
4possible side effects
- Restlessness13%
- Sedation8%
- Tremor6%
- Difficulty controlling movements5%
10possible side effects
- Sleepiness22%
- Trouble sleeping10%
- Difficulty controlling movements6%
- Numbness in the mouth5%
- Fatigue4%
- Dizziness4%
- Indigestion3%
- Swelling in the arms and legs3%
- Weight gain3%
- High blood pressure3%
Risks and risk factors
- Increased risk of death
- Elderly patients with dementia
- Suicidal thoughts or behavior
- Age 24 years or younger
- Use of antidepressant medications
- Shaking and restlessness
- Increased blood sugar and cholesterol, and weight gain
- People with diabetes
- People with high cholesterol
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert
- Low blood pressure
- Higher risk of death
- People age 65 or older with dementia and psychosis
- Neuroleptic malignant syndrome
- Taking antipsychotic medications
- Difficulty controlling movements
- Weight gain and diabetes
- Changes in blood pressure and fainting
- High blood pressure
- History of heart disease
- Higher risk of infection