Compare Accolate vs. Allegra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Accolate (zafirlukast)

Prescription only

Allegra (fexofenadine)

Over-the-counter
Controls asthma.

Although it's less effective than inhaled steroid medications for controlling asthma, Accolate (zafirlukast) has less side effects.

Treats allergy symptoms.

Allegra (fexofenadine) relieves allergy symptoms without making you feel drowsy.

3.9/ 5 average rating with 24 reviewsforAllegra
Upsides
  • Can easily take as a tablet.
  • Relatively well tolerated. Serious side effects are rare.
  • Available in affordable generic form.
  • Allegra (fexofenadine) is effective at reducing symptoms for seasonal allergies and chronic hives without significant drowsiness, unlike Benadryl.
  • Approved for kids aged 6 months or older.
  • Allegra (fexofenadine) comes in many forms, like tablet, liquid, and quick-dissolving tablet.
Downsides
  • Not a first-choice medicine to control asthma.
  • People with liver problems should not take Accolate (zafirlukast).
  • Must take twice a day compared to Singulair which is only once a day.
  • Only for children 5 or older and adults.
  • You have to store Accolate (zafirlukast) in its original bottle.
  • Allegra (fexofenadine)'s effectiveness can wear off over time.
  • The dose needs to be adjusted for people with kidney problems.
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Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
Price
No pricing information available
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Reviews
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24 reviews so far
79%
saidit'sworth it
63%
saiditworked well
0%
saidit'sa big hassle

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Side effects
14possible side effects
  • Headache
    13%
  • Infection
    4%
  • Nausea
    3%
  • Diarrhea
    3%
  • Generalized pain
    2%
  • Weakness
    2%
  • Abdominal pain
    2%
  • Accidental injury
    2%
  • Dizziness
    2%
  • Muscle pain
    2%
  • Fever
    2%
  • Back pain
    2%
  • Vomiting
    2%
  • Elevated liver enzymes
    2%
See more detailed side effects
4possible side effects
  • Dizziness
    2%
  • Back Pain
    2%
  • Stomach discomfort
    2%
  • Pain in hands/feet
    2%
See more detailed side effects
Risks and risk factors
  • Liver damage
    • Liver disease
  • Not for sudden asthma attack
  • Behavior changes
    • Mental health history
  • Low white blood cells
    • Tapering or discontinuing steroids
  • Increased bleeding risk
    • Antiplatelets
    • Anticoagulation
See more detailed risks and warnings
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Brain damage from too much phenylalanine
    • History of phenylketonuria (PKU)
See more detailed risks and warnings