Compare Accolate vs. Nasonex

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Accolate (zafirlukast)

Prescription only

Nasonex (Mometasone)

Prescription only
Controls asthma.

Although it's less effective than inhaled steroid medications for controlling asthma, Accolate (zafirlukast) has less side effects.

Relieves allergy symptoms.

Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.

3.6/ 5 average rating with 675 reviewsforNasonex
  • Can easily take as a tablet.
  • Relatively well tolerated. Serious side effects are rare.
  • Available in affordable generic form.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
  • Not a first-choice medicine to control asthma.
  • People with liver problems should not take Accolate (zafirlukast).
  • Must take twice a day compared to Singulair which is only once a day.
  • Only for children 5 or older and adults.
  • You have to store Accolate (zafirlukast) in its original bottle.
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
Used for
Dosage forms
  • Pill
  • Nasal spray
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Side effects
14possible side effects
  • Headache
  • Infection
  • Nausea
  • Diarrhea
  • Generalized pain
  • Weakness
  • Abdominal pain
  • Accidental injury
  • Dizziness
  • Muscle pain
  • Fever
  • Back pain
  • Vomiting
  • Elevated liver enzymes
See more detailed side effects
1possible side effects
  • Nosebleed
See more detailed side effects
Risks and risk factors
  • Liver damage
    • Liver disease
  • Not for sudden asthma attack
  • Behavior changes
    • Mental health history
  • Low white blood cells
    • Tapering or discontinuing steroids
  • Increased bleeding risk
    • Antiplatelets
    • Anticoagulation
See more detailed risks and warnings
  • Thrush in the nose and throat
    • Long-term use
  • Changes in the nasal septum
    • Long-term use
  • Decreased wound healing
    • Surgery or trauma to the nose or sinuses
  • Glaucoma and cataracts
    • Long-term use
  • Reduced immune system
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
  • Decrease in growth in children and teenagers
    • Long-term use
    • Taking more than recommended dose
See more detailed risks and warnings