Compare Accutane vs. benzoyl peroxide
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Accutane (isotretinoin) works well against severe acne but has a lot of serious side effects. You will need to discuss the risks and benefits with your doctor.
Benzac (benzoyl peroxide) is the most effective over-the-counter treatment for mild acne.
- Works well to clear your skin when other medicines have not worked for you.
- Most people experience clear skin after just one course of treatment. Clear skin can last for some time even after you've stopped taking Accutane (isotretinoin).
- You only have to take Accutane (isotretinoin) once or twice a day.
- Available over-the-counter from many brands.
- Benzac (benzoyl peroxide) comes in many different forms and combinations with other acne products.
- Accutane (isotretinoin) can raise your blood sugar levels. Your doctor may have to monitor your sugar levels more frequently.
- If you play sports a lot, you may be at higher risk of bone fractures.
- You'll have to see your doctor every time to get a refill of Accutane (isotretinoin) because of the high risk of birth defects.
- Can cause serious bowel problems. Talk to your doctor if you experience loose stools, blood in the stools, or bad belly pain.
- Can damage your liver. Your doctor will do regular blood tests to make sure it's healthy.
- Benzac (benzoyl peroxide) increases your skin's sensitivity to the sun and may also cause dryness or stinging.
- Be careful when applying Benzac (benzoyl peroxide) to large areas since it can bleach hair, clothing, and pillow cases upon contact.
- Benzac (benzoyl peroxide) needs to be combined with other medications to effectively treat severe acne.
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- Harm to fetus
- Suicidal thoughts or behavior
- History of depression or other psychiatric condition
- High cholesterol
- Increased alcohol
- Serious skin reaction
- Bone fractures
- History of childhood osteoporosis or bone conditions
- Anorexia nervosa
- Taking anticonvulsant medicines
- Taking corticosteroids
- Problems with vitamin D breakdown
- Longer-term therapy with Accutane (isotretinoin)
- Eye problems
- History of eye problems
- Skin irritation
- Using other medicines or products that irritate the skin
- Extreme temperatures (hot or cold)
- Allergic reaction